Exosomal cell-to-cell transmission of alpha synuclein oligomers KM Danzer, LR Kranich, WP Ruf, O Cagsal-Getkin, AR Winslow, L Zhu, ... Molecular neurodegeneration 7, 1-18, 2012 | 923 | 2012 |
Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia A Freischmidt, T Wieland, B Richter, W Ruf, V Schaeffer, K Müller, ... Nature neuroscience 18 (5), 631-636, 2015 | 838 | 2015 |
Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity KM Danzer, WP Ruf, P Putcha, D Joyner, T Hashimoto, C Glabe, ... The FASEB journal 25 (1), 326, 2011 | 377 | 2011 |
Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients V Grozdanov, C Bliederhaeuser, WP Ruf, V Roth, K Fundel-Clemens, ... Acta neuropathologica 128, 651-663, 2014 | 259 | 2014 |
Hot-spot KIF5A mutations cause familial ALS D Brenner, R Yilmaz, K Müller, T Grehl, S Petri, T Meyer, J Grosskreutz, ... Brain 141 (3), 688-697, 2018 | 196 | 2018 |
Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes C Bliederhaeuser, V Grozdanov, A Speidel, L Zondler, WP Ruf, H Bayer, ... Acta neuropathologica 131, 379-391, 2016 | 172 | 2016 |
Peripheral monocytes are functionally altered and invade the CNS in ALS patients L Zondler, K Müller, S Khalaji, C Bliederhäuser, WP Ruf, V Grozdanov, ... Acta neuropathologica 132, 391-411, 2016 | 156 | 2016 |
Impaired activation of ALS monocytes by exosomes L Zondler, MS Feiler, A Freischmidt, WP Ruf, AC Ludolph, KM Danzer, ... Immunology and cell biology 95 (2), 207-214, 2017 | 53 | 2017 |
α-synuclein interacts with SOD1 and promotes its oligomerization AM Helferich, WP Ruf, V Grozdanov, A Freischmidt, MS Feiler, L Zondler, ... Molecular neurodegeneration 10, 1-16, 2015 | 45 | 2015 |
LRRK2 contributes to monocyte dysregulation in Parkinson’s disease C Bliederhaeuser, L Zondler, V Grozdanov, WP Ruf, D Brenner, ... Acta neuropathologica communications 4, 1-5, 2016 | 44 | 2016 |
T-cell dysregulation is associated with disease severity in Parkinson’s Disease D Bhatia, V Grozdanov, WP Ruf, J Kassubek, AC Ludolph, JH Weishaupt, ... Journal of neuroinflammation 18, 1-10, 2021 | 37 | 2021 |
Exacerbation of chronic inflammatory demyelinating polyneuropathy in concomitance with COVID-19 S Abu-Rumeileh, T Garibashvili, W Ruf, T Fangerau, J Kassubek, ... Journal of the Neurological Sciences 418, 117106, 2020 | 29 | 2020 |
Screening for CHCHD10 mutations in a large cohort of sporadic ALS patients: no evidence for pathogenicity of the p.P34S variant N Marroquin, S Stranz, K Müller, T Wieland, WP Ruf, SJ Brockmann, ... Brain 139 (2), e8-e8, 2016 | 22 | 2016 |
A biallelic mutation links MYORG to autosomal-recessive primary familial brain calcification Y Forouhideh, K Müller, W Ruf, M Assi, T Şeker, C Tunca, A Knehr, ... Brain 142 (2), e4-e4, 2019 | 18 | 2019 |
Spreading of alpha-synuclein between different cell types WP Ruf, JL Meirelles, KM Danzer Behavioural brain research 436, 114059, 2023 | 12 | 2023 |
Protein binding partners of dysregulated miRNAs in Parkinson’s disease serum WP Ruf, A Freischmidt, V Grozdanov, V Roth, SJ Brockmann, ... Cells 10 (4), 791, 2021 | 12 | 2021 |
Effects of tofersen treatment in patients with SOD1-ALS in a “real-world” setting–a 12-month multicenter cohort study from the German early access program M Wiesenfarth, J Dorst, D Brenner, Z Elmas, Ö Parlak, Z Uzelac, ... EClinicalMedicine 69, 2024 | 11 | 2024 |
Spectrum and frequency of genetic variants in sporadic amyotrophic lateral sclerosis WP Ruf, M Boros, A Freischmidt, D Brenner, V Grozdanov, J de Meirelles, ... Brain Communications 5 (3), fcad152, 2023 | 10 | 2023 |
Methylome analysis of ALS patients and presymptomatic mutation carriers in blood cells WP Ruf, E Hannon, A Freischmidt, V Grozdanov, D Brenner, K Müller, ... Neurobiology of aging 116, 16-24, 2022 | 9 | 2022 |
Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease WP Ruf, A Palmer, L Dörfer, D Wiesner, E Buck, V Grozdanov, J Kassubek, ... Neurobiology of disease 174, 105877, 2022 | 3 | 2022 |