SARS-CoV-2 productively infects human gut enterocytes MM Lamers, J Beumer, J van der Vaart, K Knoops, J Puschhof, ... Science 369 (6499), 50-54, 2020 | 1722 | 2020 |
Mutational signature in colorectal cancer caused by genotoxic pks+E. coli C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ... Nature 580 (7802), 269-273, 2020 | 730 | 2020 |
Cell fate specification and differentiation in the adult mammalian intestine J Beumer, H Clevers Nature reviews Molecular cell biology 22 (1), 39-53, 2021 | 401 | 2021 |
Induced quiescence of Lgr5+ stem cells in intestinal organoids enables differentiation of hormone-producing enteroendocrine cells O Basak, J Beumer, K Wiebrands, H Seno, A van Oudenaarden, ... Cell stem cell 20 (2), 177-190. e4, 2017 | 318 | 2017 |
Regulation and plasticity of intestinal stem cells during homeostasis and regeneration J Beumer, H Clevers Development 143 (20), 3639-3649, 2016 | 306 | 2016 |
Identification of enteroendocrine regulators by real-time single-cell differentiation mapping H Gehart, JH van Es, K Hamer, J Beumer, K Kretzschmar, JF Dekkers, ... Cell 176 (5), 1158-1173. e16, 2019 | 270 | 2019 |
Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient J Beumer, B Artegiani, Y Post, F Reimann, F Gribble, TN Nguyen, H Zeng, ... Nature cell biology 20 (8), 909-916, 2018 | 232 | 2018 |
Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore, ... Nature cell biology 22 (3), 321-331, 2020 | 197 | 2020 |
An organoid‐derived bronchioalveolar model for SARS‐CoV‐2 infection of human alveolar type II‐like cells MM Lamers, J van Der Vaart, K Knoops, S Riesebosch, TI Breugem, ... The EMBO Journal 40 (5), e105912, 2021 | 189 | 2021 |
Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67‐RFP allele O Basak, M van de Born, J Korving, J Beumer, S van der Elst, JH van Es, ... The EMBO journal 33 (18), 2057-2068, 2014 | 171 | 2014 |
High-resolution mRNA and secretome atlas of human enteroendocrine cells J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ... Cell 181 (6), 1291-1306. e19, 2020 | 145 | 2020 |
Intestinal organoid cocultures with microbes J Puschhof, C Pleguezuelos-Manzano, A Martinez-Silgado, N Akkerman, ... Nature protocols 16 (10), 4633-4649, 2021 | 137 | 2021 |
Establishment and culture of human intestinal organoids derived from adult stem cells C Pleguezuelos‐Manzano, J Puschhof, S van den Brink, V Geurts, ... Current protocols in immunology 130 (1), e106, 2020 | 115 | 2020 |
Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies N Battich, J Beumer, B De Barbanson, L Krenning, CS Baron, ... Science 367 (6482), 1151-1156, 2020 | 111 | 2020 |
Snake venom gland organoids Y Post, J Puschhof, J Beumer, HM Kerkkamp, MAG de Bakker, ... Cell 180 (2), 233-247. e21, 2020 | 103 | 2020 |
A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... Nature communications 12 (1), 5498, 2021 | 70 | 2021 |
BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states J Beumer, J Puschhof, FY Yengej, L Zhao, A Martinez-Silgado, ... Cell Reports 38 (9), 2022 | 60 | 2022 |
Translation and replication dynamics of single RNA viruses S Boersma, HH Rabouw, LJM Bruurs, T Pavlovič, ALW van Vliet, ... Cell 183 (7), 1930-1945. e23, 2020 | 59 | 2020 |
A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium FH van der Linden, EK Mahlandt, JJG Arts, J Beumer, J Puschhof, ... Nature communications 12 (1), 7159, 2021 | 52 | 2021 |
Chuva de Sousa Lopes S, van Zon J, Tans S, Clevers H. Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing B Artegiani, D Hendriks, J Beumer, R Kok, X Zheng, I Joore Nat. Cell Biol 22, 321-331, 2020 | 52 | 2020 |