Assembly-line catalysis in bifunctional terpene synthases JL Faylo, TA Ronnebaum, DW Christianson Accounts of chemical research 54 (20), 3780-3791, 2021 | 49 | 2021 |
Structural insight on assembly-line catalysis in terpene biosynthesis JL Faylo, T van Eeuwen, HJ Kim, JJ Gorbea Colón, BA Garcia, ... Nature communications 12 (1), 3487, 2021 | 33 | 2021 |
Abnormally glycosylated MUC1 establishes a positive feedback circuit of inflammatory cytokines, mediated by NF-κB p65 and EzH2, in colitis-associated cancer S Cascio, JL Faylo, JC Sciurba, J Xue, S Ranganathan, JJ Lohmueller, ... Oncotarget 8 (62), 105284, 2017 | 16 | 2017 |
Transient prenyltransferase–cyclase association in fusicoccadiene synthase, an assembly-line terpene synthase JL Faylo, T van Eeuwen, K Gupta, K Murakami, DW Christianson Biochemistry 61 (21), 2417-2430, 2022 | 6 | 2022 |
Visualizing transiently associated catalytic domains in assembly-line biosynthesis using cryo-electron microscopy JL Faylo, DW Christianson Journal of structural biology 213 (4), 107802, 2021 | 6 | 2021 |
Structure of the prenyltransferase in bifunctional copalyl diphosphate synthase from Penicillium fellutanum reveals an open hexamer conformation MN Gaynes, TA Ronnebaum, K Schultz, JL Faylo, R Marmorstein, ... Journal of Structural Biology 216 (1), 108060, 2024 | 1 | 2024 |
MUC1 promotes an inflammatory microenvironment aggravating colitis-associated tumorigenesis in mice through up-regulation of pro-inflammatory cytokines. S Cascio, J Faylo, J Sciurba, J Xue, OJ Finn The Journal of Immunology 196 (1_Supplement), 73.7-73.7, 2016 | 1 | 2016 |
Assembly‐line catalysis in bifunctional terpene synthases: (+)‐Copalyl diphosphate synthase from fungal Penicillium species TA Ronnebaum, SA Eaton, EAE Brackhahn, JL Faylo, K Gupta, ... The FASEB Journal 36, 2022 | | 2022 |
Structural Biology of Oligomeric Assembly-Line Terpene Synthases JL Faylo University of Pennsylvania, 2021 | | 2021 |
Data for EMSL Project 51230 from March 2020 J Faylo, D Christianson, T Humphreys Pacific Northwest National Lab.(PNNL), Richland, WA (United States …, 2020 | | 2020 |
Validation of hypoglycosylated MUC1-CIN85 protein-protein interaction as a new therapeutic target for prevention of cancer invasion and metastasis S Cascio, J Faylo, R Sriram, A Vlad, C Camacho, OJ Finn Cancer Research 77 (13_Supplement), 4126-4126, 2017 | | 2017 |
Targeting binding of hypoglycosylated MUC1 to CIN85 to control tumor growth and prevent invasion and metastasis S Cascio, J Faylo, A Vlad, C Camacho, O Finn GLYCOBIOLOGY 26 (12), 1445-1445, 2016 | | 2016 |
Abnormal expression of MUC1 mucin on colon epithelia stimulates production of pro-inflammatory cytokines promoting colitis-associated colon cancer in a murine model S Cascio, J Faylo, J Xue, O Finn Cancer Research 76 (14_Supplement), 4153-4153, 2016 | | 2016 |