The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin RJ Shaw, KA Lamia, D Vasquez, SH Koo, N Bardeesy, RA DePinho, ... Science 310 (5754), 1642-1646, 2005 | 2354 | 2005 |
The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism SH Koo, L Flechner, L Qi, X Zhang, RA Screaton, S Jeffries, S Hedrick, ... Nature 437 (7062), 1109-1114, 2005 | 1207 | 2005 |
Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues X Zhang, DT Odom, SH Koo, MD Conkright, G Canettieri, J Best, H Chen, ... Proceedings of the National Academy of Sciences 102 (12), 4459-4464, 2005 | 1150 | 2005 |
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 SH Koo, H Satoh, S Herzig, CH Lee, S Hedrick, R Kulkarni, RM Evans, ... Nature medicine 10 (5), 530-534, 2004 | 687 | 2004 |
Regulation of glucose metabolism from a liver-centric perspective HS Han, G Kang, JS Kim, BH Choi, SH Koo Experimental & molecular medicine 48 (3), e218-e218, 2016 | 674 | 2016 |
FoxO1 regulates multiple metabolic pathways in the liver: effects on gluconeogenic, glycolytic, and lipogenic gene expression W Zhang, S Patil, B Chauhan, S Guo, DR Powell, J Le, A Klotsas, ... Journal of Biological Chemistry 281 (15), 10105-10117, 2006 | 623 | 2006 |
Nonalcoholic fatty liver disease: molecular mechanisms for the hepatic steatosis SH Koo Clinical and molecular hepatology 19 (3), 210, 2013 | 494 | 2013 |
Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2 R Dentin, Y Liu, SH Koo, S Hedrick, T Vargas, J Heredia, J Yates III, ... Nature 449 (7160), 366-369, 2007 | 487 | 2007 |
CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-γ S Herzig, S Hedrick, I Morantte, SH Koo, F Galimi, M Montminy Nature 426 (6963), 190-193, 2003 | 364 | 2003 |
CREB and FoxO1: two transcription factors for the regulation of hepatic gluconeogenesis KJ Oh, HS Han, MJ Kim, SH Koo BMB reports 46 (12), 567, 2013 | 253 | 2013 |
Regulation of hepatic gluconeogenesis by an ER-bound transcription factor, CREBH MW Lee, D Chanda, J Yang, H Oh, SS Kim, YS Yoon, S Hong, KG Park, ... Cell metabolism 11 (4), 331-339, 2010 | 227 | 2010 |
Glucose and insulin function through two distinct transcription factors to stimulate expression of lipogenic enzyme genes in liver SH Koo, AK Dutcher, HC Towle Journal of Biological Chemistry 276 (12), 9437-9445, 2001 | 212 | 2001 |
Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase MM Magaña, SH Koo, HC Towle, TF Osborne Journal of Biological Chemistry 275 (7), 4726-4733, 2000 | 181 | 2000 |
Systemic autophagy insufficiency compromises adaptation to metabolic stress and facilitates progression from obesity to diabetes YM Lim, H Lim, KY Hur, W Quan, HY Lee, H Cheon, D Ryu, SH Koo, ... Nature communications 5 (1), 4934, 2014 | 180 | 2014 |
AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB· CRTC2 complex by orphan nuclear receptor small heterodimer partner JM Lee, WY Seo, KH Song, D Chanda, YD Kim, DK Kim, MW Lee, D Ryu, ... Journal of Biological Chemistry 285 (42), 32182-32191, 2010 | 171 | 2010 |
RORα induces KLF4-mediated M2 polarization in the liver macrophages that protect against nonalcoholic steatohepatitis YH Han, HJ Kim, H Na, MW Nam, JY Kim, JS Kim, SH Koo, MO Lee Cell reports 20 (1), 124-135, 2017 | 144 | 2017 |
Phylogenetic group distributions, virulence factors and antimicrobial resistance properties of uropathogenic Escherichia coli strains isolated from patients with … JH Lee, B Subhadra, YJ Son, DH Kim, HS Park, JM Kim, SH Koo, MH Oh, ... Letters in applied microbiology 62 (1), 84-90, 2016 | 142 | 2016 |
Involvement of a unique carbohydrate-responsive factor in the glucose regulation of rat liver fatty-acid synthase gene transcription C Rufo, M Teran-Garcia, MT Nakamura, SH Koo, HC Towle, SD Clarke Journal of Biological Chemistry 276 (24), 21969-21975, 2001 | 138 | 2001 |
Orphan nuclear receptor estrogen-related receptor γ (ERRγ) is key regulator of hepatic gluconeogenesis DK Kim, D Ryu, M Koh, MW Lee, D Lim, MJ Kim, YH Kim, WJ Cho, ... Journal of Biological Chemistry 287 (26), 21628-21639, 2012 | 137 | 2012 |
PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells HS Kim, YC Hwang, SH Koo, KS Park, MS Lee, KW Kim, MK Lee PloS one 8 (1), e50128, 2013 | 119 | 2013 |