Heparan sulfate assists SARS-CoV-2 in cell entry and can be targeted by approved drugs in vitro Q Zhang, CZ Chen, M Swaroop, M Xu, L Wang, J Lee, AQ Wang, ... Cell Discovery 6 (1), 1-14, 2020 | 212 | 2020 |
A myosin-7B–dependent endocytosis pathway mediates cellular entry of α-synuclein fibrils and polycation-bearing cargos Q Zhang, Y Xu, J Lee, M Jarnik, X Wu, JS Bonifacino, J Shen, Y Ye Proceedings of the National Academy of Sciences 117 (20), 10865-10875, 2020 | 45 | 2020 |
Efficient identification of anti-SARS-CoV-2 compounds using chemical structure-and biological activity-based modeling T Xu, M Xu, W Zhu, CZ Chen, Q Zhang, W Zheng, R Huang Journal of medicinal chemistry 65 (6), 4590-4599, 2022 | 16 | 2022 |
Alignment of the protein substrate hairpin along the SecA two-helix finger primes protein transport in Escherichia coli Q Zhang, S Lahiri, T Banerjee, Z Sun, D Oliver, I Mukerji Proceedings of the National Academy of Sciences 114 (35), 9343-9348, 2017 | 15 | 2017 |
Conserved SecA Signal Peptide-Binding Site Revealed by Engineered Protein Chimeras and Forster Resonance Energy Transfer Q Zhang, Y Li, R Olson, I Mukerji, D Oliver Biochemistry 55 (9), 1291-1300, 2016 | 13 | 2016 |
Mitoxantrone modulates a heparan sulfate-spike complex to inhibit SARS-CoV-2 infection Q Zhang, P Radvak, J Lee, Y Xu, V Cao-Dao, M Xu, W Zheng, CZ Chen, ... Scientific Reports 12 (1), 6294, 2022 | 12 | 2022 |
Photocytotoxicity of hypocrellin B (HB) was enhanced by liposomalization in vitro Z Zhou, L Zhang, H Liu, Q Zhang, B Liu, P Ai, H Ma, W Liu, Z Li, W Sheng, ... International Journal of Toxicology 30 (2), 174-180, 2011 | 10 | 2011 |
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation Q Zhang, W Tang, E Stancanelli, E Jung, Z Syed, V Pagadala, L Saidi, ... Nature communications 14 (1), 5777, 2023 | 5 | 2023 |
Graph convolutional network-based screening strategy for rapid identification of SARS-CoV-2 cell-entry inhibitors P Gao, M Xu, Q Zhang, CZ Chen, H Guo, Y Ye, W Zheng, M Shen Journal of chemical information and modeling 62 (8), 1988-1997, 2022 | 4 | 2022 |
Therapeutic development targeting host heparan sulfate proteoglycan in SARS-CoV-2 infection Q Zhang, I Pavlinov, Y Ye, W Zheng Frontiers in Medicine 11, 1364657, 2024 | 3 | 2024 |
Chaperoning transmembrane helices in the lipid bilayer Q Zhang, Y Ye The Journal of Cell Biology 220 (1), 2021 | 3 | 2021 |
Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates P Gao, Q Zhang, D Keely, DW Cleveland, Y Ye, W Zheng, M Shen, H Yu Journal of medicinal chemistry 66 (22), 15084-15093, 2023 | 2 | 2023 |