| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 997 | 2022 |
| Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology J Chapuis, F Hansmannel, M Gistelinck, A Mounier, ... Molecular psychiatry 18 (11), 1225-1234, 2013 | 411 | 2013 |
| Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease J Chapuis, D Hot, F Hansmannel, O Kerdraon, S Ferreira, C Hubans, ... Molecular psychiatry 14 (11), 1004-1016, 2009 | 240 | 2009 |
| The new genetic landscape of Alzheimer’s disease: from amyloid cascade to genetically driven synaptic failure hypothesis? P Dourlen, D Kilinc, N Malmanche, J Chapuis, JC Lambert Acta neuropathologica 138, 221-236, 2019 | 162 | 2019 |
| Functional screening of Alzheimer risk loci identifies PTK2B as an in vivo modulator and early marker of Tau pathology P Dourlen, FJ Fernandez-Gomez, C Dupont, B Grenier-Boley, ... Molecular psychiatry 22 (6), 874-883, 2017 | 126 | 2017 |
| TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila LV Broeck, M Naval-Sanchez, Y Adachi, D Diaper, P Dourlen, J Chapuis, ... Cell reports 3 (1), 160-172, 2013 | 85 | 2013 |
| Tau phosphorylation regulates the interaction between BIN1’s SH3 domain and Tau’s proline-rich domain Y Sottejeau, A Bretteville, FX Cantrelle, N Malmanche, F Demiaute, ... Acta neuropathologica communications 3, 1-12, 2015 | 82 | 2015 |
| Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism J Chapuis, A Flaig, B Grenier-Boley, F Eysert, V Pottiez, G Deloison, ... Acta neuropathologica 133, 955-966, 2017 | 64 | 2017 |
| BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation M Sartori, T Mendes, S Desai, A Lasorsa, A Herledan, N Malmanche, ... Acta neuropathologica 138, 631-652, 2019 | 61 | 2019 |
| Evidence for induction of the ornithine transcarbamylase expression in Alzheimer's disease F Bensemain, D Hot, S Ferreira, J Dumont, S Bombois, CA Maurage, ... Molecular psychiatry 14 (1), 106-116, 2009 | 58 | 2009 |
| Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease J Chapuis, J Tian, J Shi, F Bensemain, D Cottel, C Lendon, P Amouyel, ... Neurobiology of aging 27 (9), 1212-1215, 2006 | 53 | 2006 |
| ADAM30 downregulates APP-linked defects through cathepsin D activation in Alzheimer's disease F Letronne, G Laumet, AM Ayral, J Chapuis, F Demiautte, M Laga, ... EBioMedicine 9, 278-292, 2016 | 44 | 2016 |
| A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly V Chouraki, R De Bruijn, J Chapuis, JC Bis, C Reitz, S Schraen, ... Molecular psychiatry 19 (12), 1326-1335, 2014 | 36 | 2014 |
| Association study of the GAB2 gene with the risk of developing Alzheimer's disease J Chapuis, D Hannequin, F Pasquier, P Bentham, A Brice, I Leber, ... Neurobiology of disease 30 (1), 103-106, 2008 | 36 | 2008 |
| The Alzheimer susceptibility gene BIN1 induces isoform-dependent neurotoxicity through early endosome defects E Lambert, O Saha, B Soares Landeira, AR Melo de Farias, X Hermant, ... Acta Neuropathologica Communications 10 (1), 4, 2022 | 35 | 2022 |
| Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner F Eysert, A Coulon, E Boscher, AC Vreulx, A Flaig, T Mendes, S Hughes, ... Molecular psychiatry 26 (10), 5592-5607, 2021 | 35 | 2021 |
| Association study of the PIN1 gene with Alzheimer's disease JC Lambert, F Bensemain, J Chapuis, D Cottel, P Amouyel Neuroscience letters 402 (3), 259-261, 2006 | 35 | 2006 |
| Association study of the paraoxonase 1 gene with the risk of developing Alzheimer's disease J Chapuis, M Boscher, F Bensemain, D Cottel, P Amouyel, JC Lambert Neurobiology of aging 30 (1), 152-156, 2009 | 32 | 2009 |
| Association study of the Ubiquilin gene with Alzheimer's disease F Bensemain, J Chapuis, J Tian, J Shi, U Thaker, C Lendon, T Iwatsubo, ... Neurobiology of disease 22 (3), 691-693, 2006 | 32 | 2006 |
| Functional complementation in Drosophila to predict the pathogenicity of TARDBP variants: evidence for a loss-of-function mechanism LV Broeck, G Kleinberger, J Chapuis, M Gistelinck, P Amouyel, ... Neurobiology of Aging 36 (2), 1121-1129, 2015 | 30 | 2015 |
