Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Aβ PA Adlard, RA Cherny, DI Finkelstein, E Gautier, E Robb, M Cortes, ... Neuron 59 (1), 43-55, 2008 | 788 | 2008 |
Chitosan nanoparticles enhance the intestinal absorption of the green tea catechins (+)-catechin and (−)-epigallocatechin gallate A Dube, JA Nicolazzo, I Larson European Journal of Pharmaceutical Sciences 41 (2), 219-225, 2010 | 315 | 2010 |
Buccal penetration enhancers—how do they really work? JA Nicolazzo, BL Reed, BC Finnin Journal of controlled release 105 (1-2), 1-15, 2005 | 273 | 2005 |
Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution A Dube, K Ng, JA Nicolazzo, I Larson Food chemistry 122 (3), 662-667, 2010 | 210 | 2010 |
Expression of tryptophan 2, 3-dioxygenase and production of kynurenine pathway metabolites in triple transgenic mice and human Alzheimer's disease brain W Wu, JA Nicolazzo, L Wen, R Chung, R Stankovic, SS Bao, CK Lim, ... PloS one 8 (4), e59749, 2013 | 174 | 2013 |
Chitosan nanoparticles enhance the plasma exposure of (−)-epigallocatechin gallate in mice through an enhancement in intestinal stability A Dube, JA Nicolazzo, I Larson European Journal of Pharmaceutical Sciences 44 (3), 422-426, 2011 | 159 | 2011 |
Methods to assess drug permeability across the blood‐brain barrier JA Nicolazzo, SA Charman, WN Charman Journal of pharmacy and pharmacology 58 (3), 281-293, 2006 | 148 | 2006 |
Fatty acid-binding protein 5 facilitates the blood–brain barrier transport of docosahexaenoic acid Y Pan, MJ Scanlon, Y Owada, Y Yamamoto, CJH Porter, JA Nicolazzo Molecular pharmaceutics 12 (12), 4375-4385, 2015 | 120 | 2015 |
Enhancing the buccal mucosal delivery of peptide and protein therapeutics T Caon, L Jin, CMO Simões, RS Norton, JA Nicolazzo Pharmaceutical research 32, 1-21, 2015 | 114 | 2015 |
The effect of various in vitro conditions on the permeability characteristics of the buccal mucosa JA Nicolazzo, BL Reed, BC Finnin Journal of pharmaceutical sciences 92 (12), 2399-2410, 2003 | 103 | 2003 |
Impact of aging, Alzheimer's disease and Parkinson's disease on the blood-brain barrier transport of therapeutics Y Pan, JA Nicolazzo Advanced drug delivery reviews 135, 62-74, 2018 | 100 | 2018 |
Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2) JA Nicolazzo, K Katneni Current topics in medicinal chemistry 9 (2), 130-147, 2009 | 79 | 2009 |
Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol JA Nicolazzo, BL Reed, BC Finnin Journal of pharmaceutical sciences 93 (2), 431-440, 2004 | 78 | 2004 |
Fatty acid-binding protein 5 at the blood–brain barrier regulates endogenous brain docosahexaenoic acid levels and cognitive function Y Pan, JL Short, KHC Choy, AX Zeng, PJ Marriott, Y Owada, MJ Scanlon, ... Journal of Neuroscience 36 (46), 11755-11767, 2016 | 76 | 2016 |
Synergistic enhancement of testosterone transdermal delivery JA Nicolazzo, TM Morgan, BL Reed, BC Finnin Journal of controlled release 103 (3), 577-585, 2005 | 75 | 2005 |
Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer’s disease DC Mehta, JL Short, JA Nicolazzo Pharmaceutical research 30, 2868-2879, 2013 | 67 | 2013 |
Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide JA Nicolazzo, BL Reed, BC Finnin Journal of controlled release 105 (3), 240-248, 2005 | 61 | 2005 |
Synthesis, structure–activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase SJ Mountford, AL Albiston, WN Charman, L Ng, JK Holien, MW Parker, ... Journal of medicinal chemistry 57 (4), 1368-1377, 2014 | 56 | 2014 |
Memantine Transport across the Mouse Blood–Brain Barrier Is Mediated by a Cationic Influx H+ Antiporter DC Mehta, JL Short, JA Nicolazzo Molecular pharmaceutics 10 (12), 4491-4498, 2013 | 55 | 2013 |
The lymphatic system plays a major role in the intravenous and subcutaneous pharmacokinetics of trastuzumab in rats AM Dahlberg, LM Kaminskas, A Smith, JA Nicolazzo, CJH Porter, ... Molecular pharmaceutics 11 (2), 496-504, 2014 | 51 | 2014 |