Active-site mutations in the South African human immunodeficiency virus type 1 subtype C protease have a significant impact on clinical inhibitor binding: kinetic and … S Mosebi, L Morris, HW Dirr, Y Sayed Journal of virology 82 (22), 11476-11479, 2008 | 49 | 2008 |
Novel furocoumarins as potential HIV-1 integrase inhibitors TO Olomola, S Mosebi, R Klein, T Traut-Johnstone, J Coates, R Hewer, ... Bioorganic chemistry 57, 1-4, 2014 | 46 | 2014 |
Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study DC Kuhnert, Y Sayed, S Mosebi, M Sayed, T Sewell, HW Dirr Journal of molecular biology 349 (4), 825-838, 2005 | 43 | 2005 |
Residue 219 impacts on the dynamics of the C-terminal region in glutathione transferase A1-1: implications for stability and catalytic and ligandin functions S Mosebi, Y Sayed, J Burke, HW Dirr Biochemistry 42 (51), 15326-15332, 2003 | 31 | 2003 |
Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogens TJ Rashamuse, AT Harrison, S Mosebi, S van Vuuren, EM Coyanis, ... Bioorganic & Medicinal Chemistry 28 (1), 115210, 2020 | 23 | 2020 |
Modification of HIV-1 reverse transcriptase and integrase activity by gold (III) complexes in direct biochemical assays M Mphahlele, M Papathanasopoulos, MA Cinellu, M Coyanis, S Mosebi, ... Bioorganic & medicinal chemistry 20 (1), 401-407, 2012 | 21 | 2012 |
Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester–AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors MH Manyeruke, TO Olomola, S Majumder, S Abrahams, M Isaacs, ... Bioorganic & Medicinal Chemistry 23 (24), 7521-7528, 2015 | 17 | 2015 |
Characterization of the binding of 8-anilinonaphthalene sulfonate to rat class Mu GST M1-1 N Kinsley, Y Sayed, S Mosebi, RN Armstrong, HW Dirr Biophysical chemistry 137 (2-3), 100-104, 2008 | 17 | 2008 |
The evaluation of statins as potential inhibitors of the LEDGF/p75–HIV‐1 integrase interaction AT Harrison, FH Kriel, MA Papathanasopoulos, S Mosebi, S Abrahams, ... Chemical Biology & Drug Design 85 (3), 290-295, 2015 | 16 | 2015 |
Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu–CD74 interaction DA Le Noury, S Mosebi, MA Papathanasopoulos, R Hewer Cellular Immunology 298 (1-2), 25-32, 2015 | 14 | 2015 |
Design, synthesis and biological evaluation of novel 2-(5-aryl-1H-imidazol-1-yl) derivatives as potential inhibitors of the HIV-1 Vpu and host BST-2 protein interaction TJ Rashamuse, Z Njengele, EM Coyanis, Y Sayed, S Mosebi, ML Bode European Journal of Medicinal Chemistry 190, 112111, 2020 | 12 | 2020 |
The effects of temperature on streptavidin-biotin binding using affinity isothermal titration calorimetry KL Mpye, S Gildenhuys, S Mosebi AIMS Biophysics 7 (4), 236-247, 2020 | 12 | 2020 |
Molecular Mechanisms of HIV Protease Inhibitors Against HPV-Associated Cervical Cancer: Restoration of TP53 Tumour Suppressor Activities L Makgoo, S Mosebi, Z Mbita Frontiers in Molecular Biosciences 9, 875208, 2022 | 10 | 2022 |
A review of the nucleic acid-based lateral flow assay for detection of breast cancer from circulating biomarkers at a point-of-care in low income countries B Dyan, PP Seele, A Skepu, PS Mdluli, S Mosebi, NRS Sibuyi Diagnostics 12 (8), 1973, 2022 | 9 | 2022 |
Screening of the NIH Clinical Collection for inhibitors of HIV-1 integrase activity S Abrahams, S Mosebi, MQ Fish, MA Papathanasopoulos, R Hewer South African Journal of Science 114 (3-4), 1-5, 2018 | 8 | 2018 |
Expression, purification and characterization of a full-length recombinant HIV-1 Vpu from inclusion bodies Z Njengele, R Kleynhans, Y Sayed, S Mosebi Protein Expression and Purification 128, 109-114, 2016 | 8 | 2016 |
Long noncoding RNAs (lncRNAs) in HIV-mediated carcinogenesis: Role in cell homeostasis, cell survival processes and drug resistance L Makgoo, S Mosebi, Z Mbita Non-coding RNA research 7 (3), 184-196, 2022 | 3 | 2022 |
Active site mutations in the South African HIV-1 subtype C protease impact significantly on clinical inhibitor binding: a kinetic and thermodynamic study S Mosebi, L Morris, HW Dirr, Y Sayed J. Virol 82, 11476-11479, 2008 | 3 | 2008 |
HIV protease hinge region insertions at codon 38 affect enzyme kinetics, conformational stability and dynamics Z Sheik Ismail, R Worth, S Mosebi, Y Sayed The Protein Journal 42 (5), 490-501, 2023 | 2 | 2023 |
The Role of Death-Associated Protein Kinase-1 in Cell Homeostasis-Related Processes L Makgoo, S Mosebi, Z Mbita Genes 14 (6), 1274, 2023 | 2 | 2023 |