关注
Erika Pearce
Erika Pearce
在 jhmi.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Metabolic competition in the tumor microenvironment is a driver of cancer progression
CH Chang, J Qiu, D O’Sullivan, MD Buck, T Noguchi, JD Curtis, Q Chen, ...
Cell 162 (6), 1229-1241, 2015
26752015
Posttranscriptional control of T cell effector function by aerobic glycolysis
CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ...
Cell 153 (6), 1239-1251, 2013
21312013
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
MM Gubin, X Zhang, H Schuster, E Caron, JP Ward, T Noguchi, Y Ivanova, ...
Nature 515 (7528), 577-581, 2014
21302014
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
EL Pearce, MC Walsh, PJ Cejas, GM Harms, H Shen, LS Wang, ...
Nature 460 (7251), 103-107, 2009
16942009
Metabolic pathways in immune cell activation and quiescence
EL Pearce, EJ Pearce
Immunity 38 (4), 633-643, 2013
16042013
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
GJW van der Windt, B Everts, CH Chang, JD Curtis, TC Freitas, E Amiel, ...
Immunity 36 (1), 68-78, 2012
15262012
Fueling immunity: insights into metabolism and lymphocyte function
EL Pearce, MC Poffenberger, CH Chang, RG Jones
Science 342 (6155), 1242454, 2013
13712013
Control of effector CD8+ T cell function by the transcription factor Eomesodermin
EL Pearce, AC Mullen, GA Martins, CM Krawczyk, AS Hutchins, ...
Science 302 (5647), 1041-1043, 2003
12472003
Mitochondrial dynamics controls T cell fate through metabolic programming
MD Buck, D O’Sullivan, RIK Geltink, JD Curtis, CH Chang, DE Sanin, ...
Cell 166 (1), 63-76, 2016
12392016
T cell metabolism drives immunity
MD Buck, D O’sullivan, EL Pearce
Journal of Experimental Medicine 212 (9), 1345-1360, 2015
11542015
TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation
B Everts, E Amiel, SCC Huang, AM Smith, CH Chang, WY Lam, ...
Nature immunology 15 (4), 323-332, 2014
10622014
Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
SCC Huang, B Everts, Y Ivanova, D O'sullivan, M Nascimento, AM Smith, ...
Nature immunology 15 (9), 846-855, 2014
10552014
Metabolic instruction of immunity
MD Buck, RT Sowell, SM Kaech, EL Pearce
Cell 169 (4), 570-586, 2017
10292017
Memory CD8+ T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development
D O’Sullivan, GJW van der Windt, SCC Huang, JD Curtis, CH Chang, ...
Immunity 41 (1), 75-88, 2014
7932014
The colonic crypt protects stem cells from microbiota-derived metabolites
GE Kaiko, SH Ryu, OI Koues, PL Collins, L Solnica-Krezel, EJ Pearce, ...
Cell 165 (7), 1708-1720, 2016
6702016
Unraveling the complex interplay between T cell metabolism and function
RI Klein Geltink, RL Kyle, EL Pearce
Annual review of immunology 36, 461-488, 2018
6652018
The energy sensor AMPK regulates T cell metabolic adaptation and effector responses in vivo
J Blagih, F Coulombe, EE Vincent, F Dupuy, G Galicia-Vázquez, ...
Immunity 42 (1), 41-54, 2015
6332015
Metabolic switching and fuel choice during T‐cell differentiation and memory development
GJW van der Windt, EL Pearce
Immunological reviews 249 (1), 27-42, 2012
5932012
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
B Everts, E Amiel, GJW Van Der Windt, TC Freitas, R Chott, ...
Blood, The Journal of the American Society of Hematology 120 (7), 1422-1431, 2012
5792012
Metabolic reprogramming mediated by the mTORC2-IRF4 signaling axis is essential for macrophage alternative activation
SCC Huang, AM Smith, B Everts, M Colonna, EL Pearce, JD Schilling, ...
Immunity 45 (4), 817-830, 2016
5432016
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