| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415-421, 2013 | 9884 | 2013 |
| Massive genomic rearrangement acquired in a single catastrophic event during cancer development PJ Stephens, CD Greenman, B Fu, F Yang, GR Bignell, LJ Mudie, ... cell 144 (1), 27-40, 2011 | 2603 | 2011 |
| Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2195 | 2016 |
| Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 2078 | 2012 |
| The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012 | 1924 | 2012 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1749* | 2020 |
| The patterns and dynamics of genomic instability in metastatic pancreatic cancer PJ Campbell, S Yachida, LJ Mudie, PJ Stephens, ED Pleasance, ... Nature 467 (7319), 1109-1113, 2010 | 1560 | 2010 |
| The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1559 | 2012 |
| Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts E Papaemmanuil, M Cazzola, J Boultwood, L Malcovati, P Vyas, D Bowen, ... New England Journal of Medicine 365 (15), 1384-1395, 2011 | 1436 | 2011 |
| A small-cell lung cancer genome with complex signatures of tobacco exposure ED Pleasance, PJ Stephens, S O’Meara, DJ McBride, A Meynert, D Jones, ... Nature 463 (7278), 184-190, 2010 | 1282 | 2010 |
| Deciphering signatures of mutational processes operative in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, PJ Campbell, MR Stratton Cell reports 3 (1), 246-259, 2013 | 1267 | 2013 |
| Mutational signatures associated with tobacco smoking in human cancer LB Alexandrov, YS Ju, K Haase, P Van Loo, I Martincorena, S Nik-Zainal, ... Science 354 (6312), 618-622, 2016 | 1043 | 2016 |
| Clock-like mutational processes in human somatic cells LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ... Nature genetics 47 (12), 1402-1407, 2015 | 993 | 2015 |
| Heterogeneity of genomic evolution and mutational profiles in multiple myeloma N Bolli, H Avet-Loiseau, DC Wedge, P Van Loo, LB Alexandrov, ... Nature communications 5 (1), 2997, 2014 | 964 | 2014 |
| HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ... Nature medicine 23 (4), 517-525, 2017 | 941 | 2017 |
| Mechanisms underlying mutational signatures in human cancers T Helleday, S Eshtad, S Nik-Zainal Nature reviews genetics 15 (9), 585-598, 2014 | 941 | 2014 |
| Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature medicine 21 (7), 751-759, 2015 | 841 | 2015 |
| Recurrent rearrangements of chromosome 1q21. 1 and variable pediatric phenotypes HC Mefford, AJ Sharp, C Baker, A Itsara, Z Jiang, K Buysse, S Huang, ... New England Journal of Medicine 359 (16), 1685-1699, 2008 | 838 | 2008 |
| Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone S Behjati, PS Tarpey, N Presneau, S Scheipl, N Pillay, P Van Loo, ... Nature genetics 45 (12), 1479-1482, 2013 | 796 | 2013 |
| A compendium of mutational signatures of environmental agents JE Kucab, X Zou, S Morganella, M Joel, AS Nanda, E Nagy, C Gomez, ... Cell 177 (4), 821-836. e16, 2019 | 523 | 2019 |
