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| Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily KP Hopfner, A Karcher, DS Shin, L Craig, LM Arthur, JP Carney, JA Tainer Cell 101 (7), 789-800, 2000 | 1192 | 2000 |
| Molecular mechanisms and cellular functions of cGAS–STING signalling KP Hopfner, V Hornung Nature reviews Molecular cell biology 21 (9), 501-521, 2020 | 1082 | 2020 |
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| The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair KP Hopfner, L Craig, G Moncalian, RA Zinkel, T Usui, BAL Owen, ... Nature 418 (6897), 562-566, 2002 | 712 | 2002 |
| The C-terminal regulatory domain is the RNA 5′-triphosphate sensor of RIG-I S Cui, K Eisenächer, A Kirchhofer, K Brzózka, A Lammens, K Lammens, ... Molecular cell 29 (2), 169-179, 2008 | 659 | 2008 |
| Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase KP Hopfner, A Karcher, L Craig, TT Woo, JP Carney, JA Tainer Cell 105 (4), 473-485, 2001 | 624 | 2001 |
| Modulation of protein properties in living cells using nanobodies A Kirchhofer, J Helma, K Schmidthals, C Frauer, S Cui, A Karcher, ... Nature structural & molecular biology 17 (1), 133-138, 2010 | 621 | 2010 |
| 5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I A Schmidt, T Schwerd, W Hamm, JC Hellmuth, S Cui, M Wenzel, ... Proceedings of the National Academy of Sciences 106 (29), 12067-12072, 2009 | 541 | 2009 |
| Structural biochemistry of a bacterial checkpoint protein reveals diadenylate cyclase activity regulated by DNA recombination intermediates G Witte, S Hartung, K Büttner, KP Hopfner Molecular cell 30 (2), 167-178, 2008 | 499 | 2008 |
| Cytosolic viral sensor RIG-I is a 5'-Triphosphate–dependent translocase on double-stranded RNA S Myong, S Cui, PV Cornish, A Kirchhofer, MU Gack, JU Jung, ... Science 323 (5917), 1070-1074, 2009 | 455 | 2009 |
| cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders L Andreeva, B Hiller, D Kostrewa, C Lässig, CC de Oliveira Mann, ... Nature 549 (7672), 394-398, 2017 | 421 | 2017 |
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| Structural basis for DNA duplex separation by a superfamily-2 helicase K Büttner, S Nehring, KP Hopfner Nature structural & molecular biology 14 (7), 647-652, 2007 | 359 | 2007 |
| Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses Q Liang, GJ Seo, YJ Choi, MJ Kwak, J Ge, MA Rodgers, M Shi, BJ Leslie, ... Cell host & microbe 15 (2), 228-238, 2014 | 356 | 2014 |
| Establishment of sister chromatid cohesion at the S. cerevisiae replication fork A Lengronne, J McIntyre, Y Katou, Y Kanoh, KP Hopfner, K Shirahige, ... Molecular cell 23 (6), 787-799, 2006 | 350 | 2006 |
| OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids V Hornung, R Hartmann, A Ablasser, KP Hopfner Nature Reviews Immunology 14 (8), 521-528, 2014 | 348 | 2014 |
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| Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II K Schwarz, A Iolascon, F Verissimo, NS Trede, W Horsley, W Chen, ... Nature genetics 41 (8), 936-940, 2009 | 313 | 2009 |
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