| The merger of decatungstate and copper catalysis to enable aliphatic C(sp3)–H trifluoromethylation PJ Sarver, V Bacauanu, DM Schultz, DA DiRocco, Y Lam, EC Sherer, ... Nature chemistry 12 (5), 459-467, 2020 | 248 | 2020 |
| Computational prediction of chemical reactions: current status and outlook O Engkvist, PO Norrby, N Selmi, Y Lam, Z Peng, EC Sherer, W Amberg, ... Drug discovery today 23 (6), 1203-1218, 2018 | 182 | 2018 |
| Theory and modeling of asymmetric catalytic reactions Y Lam, MN Grayson, MC Holland, A Simon, KN Houk Accounts of Chemical Research 49 (4), 750-762, 2016 | 178 | 2016 |
| Diels− Alder exo selectivity in terminal-substituted dienes and dienophiles: experimental discoveries and computational explanations Y Lam, PHY Cheong, JM Blasco Mata, SJ Stanway, V Gouverneur, ... Journal of the American Chemical Society 131 (5), 1947-1957, 2009 | 114 | 2009 |
| Electrochemical synthesis of hindered primary and secondary amines via proton-coupled electron transfer D Lehnherr, Y Lam, MC Nicastri, J Liu, JA Newman, EL Regalado, ... Journal of the American Chemical Society 142 (1), 468-478, 2019 | 100 | 2019 |
| Mechanisms and origins of periselectivity of the ambimodal [6+ 4] cycloadditions of tropone to dimethylfulvene P Yu, TQ Chen, Z Yang, CQ He, A Patel, Y Lam, CY Liu, KN Houk Journal of the American Chemical Society 139 (24), 8251-8258, 2017 | 99 | 2017 |
| Synthesis of sterically hindered primary amines by concurrent tandem photoredox catalysis MC Nicastri, D Lehnherr, Y Lam, DA DiRocco, T Rovis Journal of the American Chemical Society 142 (2), 987-998, 2020 | 98 | 2020 |
| Photomediated ring contraction of saturated heterocycles J Jurczyk, MC Lux, D Adpressa, SF Kim, Y Lam, CS Yeung, R Sarpong Science 373 (6558), 1004-1012, 2021 | 90 | 2021 |
| Origins of stereoselectivity in intramolecular aldol reactions catalyzed by cinchona amines Y Lam, KN Houk Journal of the American Chemical Society 137 (5), 2116-2127, 2015 | 88 | 2015 |
| Hydrophobic substituent effects on proline catalysis of aldol reactions in water Q Zhao, Y Lam, M Kheirabadi, C Xu, KN Houk, CE Schafmeister The Journal of organic chemistry 77 (10), 4784-4792, 2012 | 80 | 2012 |
| Enamine carboxylates as stereodetermining intermediates in prolinate catalysis JE Hein, J Burés, Y Lam, M Hughes, KN Houk, A Armstrong, ... Organic letters 13 (20), 5644-5647, 2011 | 73 | 2011 |
| How cinchona alkaloid-derived primary amines control asymmetric electrophilic fluorination of cyclic ketones Y Lam, KN Houk Journal of the American Chemical Society 136 (27), 9556-9559, 2014 | 65 | 2014 |
| Stereoselectivities of histidine-catalyzed asymmetric aldol additions and contrasts with proline catalysis: A quantum mechanical analysis Y Lam, KN Houk, U Scheffler, R Mahrwald Journal of the American Chemical Society 134 (14), 6286-6295, 2012 | 59 | 2012 |
| A concise synthesis of enantioenriched fluorinated carbocycles. Y Lam, C Bobbio, I Cooper, V Gouverneur Angewandte Chemie (International ed. in English) 46 (27), 2007 | 52 | 2007 |
| Pericyclic Cascade with chirality transfer: reaction pathway and origin of enantioselectivity of the hetero-Claisen approach to oxindoles N Çelebi-Ölçüm, Y Lam, E Richmond, KB Ling, AD Smith, KN Houk Angewandte Chemie (International ed. in English) 50 (48), 11478, 2011 | 49 | 2011 |
| Origins of the Stereoselectivity in a Thiourea–Primary Amine-Catalyzed Nazarov Cyclization AH Asari, Y Lam, MA Tius, KN Houk Journal of the American Chemical Society 137 (40), 13191-13199, 2015 | 46 | 2015 |
| An asymmetric pericyclic cascade approach to 3-alkyl-3-aryloxindoles: generality, applications and mechanistic investigations E Richmond, KB Ling, N Duguet, LB Manton, N Çelebi-Ölçüm, YH Lam, ... Organic & Biomolecular Chemistry 13 (6), 1807-1817, 2015 | 45 | 2015 |
| Discovery of amino-cyclobutarene-derived indoleamine-2, 3-dioxygenase 1 (IDO1) inhibitors for cancer immunotherapy H Zhang, K Liu, Q Pu, A Achab, MJ Ardolino, M Cheng, Y Deng, AC Doty, ... ACS medicinal chemistry letters 10 (11), 1530-1536, 2019 | 41 | 2019 |
| Organocatalysis: Fundamentals and comparisons to metal and enzyme catalysis P Vogel, Y Lam, A Simon, KN Houk Catalysts 6 (9), 128, 2016 | 41 | 2016 |
| Applications of quantum chemistry in pharmaceutical process development: Current state and opportunities Y Lam, Y Abramov, RS Ananthula, JM Elward, LR Hilden, SO Nilsson Lill, ... Organic Process Research & Development 24 (8), 1496-1507, 2020 | 39 | 2020 |
