Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt, L Pinton, LA Moyle, ... Cell Reports 23 (3), 899-908, 2018 | 271 | 2018 |
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 209 | 2018 |
Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ... Brain 142 (9), 2572-2580, 2019 | 167 | 2019 |
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... Nature communications 9 (1), 2010, 2018 | 147 | 2018 |
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis P Smethurst, E Risse, GE Tyzack, JS Mitchell, DM Taha, YR Chen, ... Brain 143 (2), 430-440, 2020 | 86 | 2020 |
Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD TG Moens, S Mizielinska, T Niccoli, JS Mitchell, A Thoeng, CE Ridler, ... Acta neuropathologica 135, 445-457, 2018 | 79 | 2018 |
Higher education for refugees in low-resource environments: Landscape review C Gladwell, D Hollow, A Robinson, B Norman, E Bowerman, J Mitchell, ... Jigsaw Consult, United Kingdom, 2016 | 55 | 2016 |
MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration R Simone, F Javad, W Emmett, OG Wilkins, FL Almeida, ... Nature 594 (7861), 117-123, 2021 | 41 | 2021 |
Potential benefits of hierarchical modes of the DVB-T specification C Nokes, J Mitchell IEE Colloquium on Digital Television-Where Is It and Where Is It Going?(Ref …, 1999 | 26 | 1999 |
Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology OJ Ziff, J Neeves, J Mitchell, G Tyzack, C Martinez-Ruiz, R Luisier, ... Nature Communications 14 (1), 2176, 2023 | 19 | 2023 |
Delineating astrocytic cytokine responses in a human stem cell model of neural trauma EP Thelin, CE Hall, GE Tyzack, A Frostell, S Giorgi-Coll, A Alam, ... Journal of Neurotrauma 37 (1), 93-105, 2020 | 18 | 2020 |
Three-dimensional human iPSC-derived artificial skeletal muscles model muscular dystrophies and enable multilineage tissue engineering. Cell Rep 23 (3): 899–908 SM Maffioletti, S Sarcar, ABH Henderson, I Mannhardt, L Pinton, LA Moyle, ... | 7 | 2018 |
A Non-Toxic Concentration of Telomerase Inhibitor BIBR1532 Fails to Reduce TERT Expression in a Feeder-Free Induced Pluripotent Stem Cell Model of Human … VA Pandya, H Crerar, JS Mitchell, R Patani International Journal of Molecular Sciences 22 (6), 3256, 2021 | 5 | 2021 |
Meta-analysis of the amyotrophic lateral sclerosis spectrum uncovers genome instability OJ Ziff, J Neeves, J Mitchell, G Tyzack, NeuroLINCS consortium, ... medRxiv, 2022.08. 11.22278516, 2022 | 4 | 2022 |
A Next-Generation, Miniaturized Rb Atomic Clock Reference for Mobile, GNSS-Denied Environments W Krzewick, J Mitchell, J Bollettiero, P Cash, K Wellwood, I Kosvin, ... Proceedings of the 2020 International Technical Meeting of The Institute of …, 2020 | 2 | 2020 |
Genome instability underlies an augmented DNA damage response in familial and sporadic ALS human iPSC-derived motor neurons O Ziff, J Neeves, J Mitchell, G Tyzack, C Ruiz, N McGranahan, R Luisier, ... | 1 | 2022 |
Investigating directed differentiation strategies in hiPSCs to model cell type-specific vulnerability in ALS JS Mitchell UCL (University College London), 2021 | | 2021 |
Establishing motor neuron and astrocytic cultures to study spinal and bulbar muscular atrophy HE Devine, B Malik, J Mitchell, L Greensmith, R Patani Neuromuscular Disorders 28, S24-S25, 2018 | | 2018 |
DISCUSSION. THE CONSTRUCTION OF AN EXPERIMENTAL PRESTRESSED CONCRETE ROAD AT WINTHORPE, NOTTINGHAMSHIRE. RA KIDD, J BROAD, J MITCHELL, JP Stott, KM BROOK, AN SPARKE, ... Proceedings of the Institution of Civil Engineers 39 (1), 137-146, 1968 | | 1968 |