| Sialic acid blockade suppresses tumor growth by enhancing T-cell–mediated tumor immunity C Büll, TJ Boltje, N Balneger, SM Weischer, M Wassink, JJ van Gemst, ... Cancer research 78 (13), 3574-3588, 2018 | 218 | 2018 |
| NANS-mediated synthesis of sialic acid is required for brain and skeletal development CDM Van Karnebeek, L Bonafé, XY Wen, M Tarailo-Graovac, S Balzano, ... Nature Genetics 48 (7), 777-784, 2016 | 152 | 2016 |
| Sialic acid mimetics to target the sialic acid–Siglec axis C Büll, T Heise, GJ Adema, TJ Boltje Trends in biochemical sciences 41 (6), 519-531, 2016 | 149 | 2016 |
| Potent metabolic sialylation inhibitors based on C-5-modified fluorinated sialic acids T Heise, JFA Pijnenborg, C Büll, N van Hilten, ED Kers-Rebel, ... Journal of Medicinal Chemistry 62 (2), 1014-1021, 2018 | 68 | 2018 |
| Steering Siglec–sialic acid interactions on living cells using bioorthogonal chemistry C Büll, T Heise, N van Hilten, JFA Pijnenborg, VRLJ Bloemendal, ... Angewandte Chemie International Edition 56 (12), 3309-3313, 2017 | 50 | 2017 |
| Sialic acid glycoengineering using an unnatural sialic acid for the detection of sialoglycan biosynthesis defects and on-cell synthesis of siglec ligands C Büll, T Heise, DMH Beurskens, M Riemersma, A Ashikov, FPJT Rutjes, ... ACS chemical biology 10 (10), 2353-2363, 2015 | 42 | 2015 |
| Metabolic sialic acid blockade lowers the activation threshold of moDCs for TLR stimulation C Büll, E Collado‐Camps, ED Kers‐Rebel, T Heise, JN Søndergaard, ... Immunology and cell biology 95 (4), 408-415, 2017 | 41 | 2017 |
| Disease mutations in CMP-sialic acid transporter SLC35A1 result in abnormal α-dystroglycan O-mannosylation, independent from sialic acid M Riemersma, J Sandrock, TJ Boltje, C Büll, T Heise, A Ashikov, ... Human molecular genetics 24 (8), 2241-2246, 2015 | 37 | 2015 |
| Selective inhibition of sialic acid-based molecular mimicry in Haemophilus influenzae abrogates serum resistance T Heise, JD Langereis, E Rossing, MI de Jonge, GJ Adema, C Büll, ... Cell Chemical Biology 25 (10), 1279-1285. e8, 2018 | 35 | 2018 |
| Metabolic oligosaccharide engineering with alkyne sialic acids confers neuraminidase resistance and inhibits influenza reproduction T Heise, C Büll, DM Beurskens, E Rossing, MI de Jonge, GJ Adema, ... Bioconjugate Chemistry 28 (7), 1811-1815, 2017 | 24 | 2017 |
| Combined sialic acid and histone deacetylase (HDAC) inhibitor treatment up-regulates the neuroblastoma antigen GD2 RJE van den Bijgaart, M Kroesen, M Wassink, IC Brok, ED Kers-Rebel, ... Journal of Biological Chemistry 294 (12), 4437-4449, 2019 | 21 | 2019 |
| Dynamic tracing of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs M van Scherpenzeel, F Conte, C Büll, A Ashikov, E Hermans, A Willems, ... Glycobiology 32 (3), 239-250, 2022 | 18 | 2022 |
| Structure–Activity Relationship of Metabolic Sialic Acid Inhibitors and Labeling Reagents SJ Moons, E Rossing, MACH Janssen, T Heise, C Büll, GJ Adema, ... ACS Chemical Biology 17 (3), 590-597, 2022 | 15 | 2022 |
| Fighting Shigella by Blocking Its Disease-Causing Toxin D Haksar, M Asadpoor, T Heise, J Shi, S Braber, G Folkerts, L Ballell, ... Journal of Medicinal Chemistry 64 (9), 6059-6069, 2021 | 9 | 2021 |
| A Divergent Method to Prepare 5‐Amino‐, 5‐N‐Acetamido‐, and 5‐N‐Glycolylsialosides TJ Boltje, T Heise, FPJT Rutjes, FL van Delft European Journal of Organic Chemistry 2013 (24), 5257-5261, 2013 | 5 | 2013 |
| Dynamic analysis of sugar metabolism reveals the mechanisms of action of synthetic sugar analogs M van Scherpenzeel, F Conte, C Büll, A Ashikov, E Hermans, A Willems, ... BioRxiv, 2020.09. 15.288712, 2020 | 4 | 2020 |
| Chemical glycobiology of sialic acid derivatives for glycocalyx engineering T Heise [Sl]:[Sn], 2018 | 1 | 2018 |
| Specific labeling of newly synthesized lipopolysaccharide via metabolic incorporation of azido-galactose Y Xu, X Wang, EA Zaal, CR Berkers, JH Lorent, T Heise, R Cox, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 159467, 2024 | | 2024 |
| Potent sialyltransferase inhibitors TJ Boltje, T Heise, JFA Pijnenborg, C Büll, GJ Adema US Patent 11,639,364, 2023 | | 2023 |
| New potent sialyltransferase inhibitors TJ Boltje, T Heise, JFA Pijnenborg, C Büll, GJ Adema [Sl]:[Sn], 2019 | | 2019 |
