Screening and large-scale expression of membrane proteins in mammalian cells for structural studies A Goehring, CH Lee, KH Wang, JC Michel, DP Claxton, I Baconguis, ... Nature protocols 9 (11), 2574-2585, 2014 | 576 | 2014 |
NMDA receptor structures reveal subunit arrangement and pore architecture CH Lee, W Lü, JC Michel, A Goehring, J Du, X Song, E Gouaux Nature 511 (7508), 191-197, 2014 | 573 | 2014 |
Structures of the human HCN1 hyperpolarization-activated channel CH Lee, R MacKinnon Cell 168 (1), 111-120. e11, 2017 | 378 | 2017 |
Mechanism of NMDA receptor channel block by MK-801 and memantine X Song, MØ Jensen, V Jogini, RA Stein, CH Lee, HS Mchaourab, ... Nature 556 (7702), 515–519, 2018 | 255 | 2018 |
Mechanism of NMDA receptor inhibition and activation S Zhu, RA Stein, C Yoshioka, CH Lee, A Goehring, HS Mchaourab, ... Cell 165 (3), 704-714, 2016 | 232 | 2016 |
Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures CH Lee, R MacKinnon Science 360 (6388), 508-513, 2018 | 175 | 2018 |
The NAD+-mediated self-inhibition mechanism of pro-neurodegenerative SARM1 Y Jiang, T Liu, CH Lee, Q Chang, J Yang, Z Zhang Nature 588 (7839), 658-663, 2020 | 158 | 2020 |
Molecular basis of V-ATPase inhibition by bafilomycin A1 R Wang, J Wang, A Hassan, CH Lee, XS Xie, X Li Nature communications 12 (1), 1782, 2021 | 121 | 2021 |
Voltage sensor movements during hyperpolarization in the HCN channel CH Lee, R MacKinnon Cell 179 (7), 1582-1589. e7, 2019 | 116 | 2019 |
Childhood amyotrophic lateral sclerosis caused by excess sphingolipid synthesis P Mohassel, S Donkervoort, MA Lone, M Nalls, K Gable, SD Gupta, ... Nature medicine 27 (7), 1197-1204, 2021 | 115 | 2021 |
Structural insights into the regulation of human serine palmitoyltransferase complexes Y Wang, Y Niu, Z Zhang, K Gable, SD Gupta, N Somashekarappa, G Han, ... Nature Structural & Molecular Biology 28 (3), 240-248, 2021 | 80 | 2021 |
Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA C Williams, W Chen, CH Lee, D Yaeger, NP Vyleta, SM Smith Nature neuroscience 15 (9), 1195-1197, 2012 | 61 | 2012 |
Calcium regulation of spontaneous and asynchronous neurotransmitter release SM Smith, W Chen, NP Vyleta, C Williams, CH Lee, C Phillips, ... Cell calcium 52 (3-4), 226-233, 2012 | 58 | 2012 |
Amino terminal domains of the NMDA receptor are organized as local heterodimers CH Lee, E Gouaux PLoS One 6 (4), e19180, 2011 | 50 | 2011 |
Activation and closed-state inactivation mechanisms of the human voltage-gated KV4 channel complexes W Ye, H Zhao, Y Dai, Y Wang, Y Lo, LY Jan, CH Lee Molecular cell 82 (13), 2427-2442. e4, 2022 | 28 | 2022 |
Ionic flow enhances low‐affinity binding: a revised mechanistic view into Mg2+ block of NMDA receptors YC Yang, CH Lee, CC Kuo The Journal of physiology 588 (4), 633-650, 2010 | 25 | 2010 |
Dynasore inhibits rapid endocytosis in bovine chromaffin cells CC Tsai, CL Lin, TL Wang, AC Chou, MY Chou, CH Lee, IW Peng, ... American Journal of Physiology-Cell Physiology 297 (2), C397-C406, 2009 | 25 | 2009 |
Mechanisms of neurotransmitter transport and drug inhibition in human VMAT2 S Pidathala, S Liao, Y Dai, X Li, C Long, CL Chang, Z Zhang, CH Lee Nature 623 (7989), 1086-1092, 2023 | 21 | 2023 |
Structural and functional insights into Spns2-mediated transport of sphingosine-1-phosphate H Chen, S Ahmed, H Zhao, N Elghobashi-Meinhardt, Y Dai, JH Kim, ... Cell 186 (12), 2644-2655. e16, 2023 | 21 | 2023 |
Specificity of TGF-β1 signal designated by LRRC33 and integrin αVβ8 Z Duan, X Lin, L Wang, Q Zhen, Y Jiang, C Chen, J Yang, CH Lee, Y Qin, ... Nature Communications 13 (1), 4988, 2022 | 17 | 2022 |