Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients P Jiang, CWM Chan, KCA Chan, SH Cheng, J Wong, VWS Wong, ... Proceedings of the National Academy of Sciences 112 (11), E1317-E1325, 2015 | 716 | 2015 |
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments K Sun, P Jiang, KCA Chan, J Wong, YKY Cheng, RHS Liang, W Chan, ... Proceedings of the National Academy of Sciences 112 (40), E5503-E5512, 2015 | 710 | 2015 |
Association between HLA‐B* 1502 allele and antiepileptic drug‐induced cutaneous reactions in Han Chinese CBL Man, P Kwan, L Baum, E Yu, KM Lau, ASH Cheng, MHL Ng Epilepsia 48 (5), 1015-1018, 2007 | 646 | 2007 |
SIRT2 overexpression in hepatocellular carcinoma mediates epithelial to mesenchymal transition by protein kinase B/glycogen synthase kinase‐3β/β‐catenin signaling J Chen, AWH Chan, KF To, W Chen, Z Zhang, J Ren, C Song, YS Cheung, ... Hepatology 57 (6), 2287-2298, 2013 | 234 | 2013 |
Sirtuin 1 is upregulated in a subset of hepatocellular carcinomas where it is essential for telomere maintenance and tumor cell growth J Chen, B Zhang, N Wong, AWI Lo, KF To, AWH Chan, MHL Ng, CYS Ho, ... Cancer research 71 (12), 4138-4149, 2011 | 217 | 2011 |
Association of human-leukocyte-antigen class I (B* 0703) and class II (DRB1* 0301) genotypes with susceptibility and resistance to the development of severe acute respiratory … MHL Ng, KM Lau, L Li, SH Cheng, WY Chan, PK Hui, B Zee, CB Leung, ... Journal of Infectious Diseases 190 (3), 515-518, 2004 | 211 | 2004 |
HLA‐B alleles associated with severe cutaneous reactions to antiepileptic drugs in H an C hinese YK Cheung, SH Cheng, EJM Chan, SV Lo, MHL Ng, P Kwan Epilepsia 54 (7), 1307-1314, 2013 | 199 | 2013 |
Orientation-aware plasma cell-free DNA fragmentation analysis in open chromatin regions informs tissue of origin K Sun, P Jiang, SH Cheng, THT Cheng, J Wong, VWS Wong, SSM Ng, ... Genome research 29 (3), 418-427, 2019 | 189 | 2019 |
Plasma DNA end-motif profiling as a fragmentomic marker in cancer, pregnancy, and transplantation P Jiang, K Sun, W Peng, SH Cheng, M Ni, PC Yeung, MMS Heung, T Xie, ... Cancer Discovery 10 (5), 664-673, 2020 | 186 | 2020 |
Increase in circulating Foxp3+ CD4+ CD25high regulatory T cells in nasopharyngeal carcinoma patients KM Lau, SH Cheng, KW Lo, S Lee, JKS Woo, CA Van Hasselt, SP Lee, ... British journal of cancer 96 (4), 617-622, 2007 | 179 | 2007 |
Second generation noninvasive fetal genome analysis reveals de novo mutations, single-base parental inheritance, and preferred DNA ends KCA Chan, P Jiang, K Sun, YKY Cheng, YK Tong, SH Cheng, AIC Wong, ... Proceedings of the National Academy of Sciences 113 (50), E8159-E8168, 2016 | 174 | 2016 |
Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis BYK Law, M Wang, DL Ma, F Al-Mousa, F Michelangeli, SH Cheng, ... Molecular cancer therapeutics 9 (3), 718-730, 2010 | 174 | 2010 |
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA L Serpas, RWY Chan, P Jiang, M Ni, K Sun, A Rashidfarrokhi, C Soni, ... Proceedings of the National Academy of Sciences 116 (2), 641-649, 2019 | 159 | 2019 |
Preferred end coordinates and somatic variants as signatures of circulating tumor DNA associated with hepatocellular carcinoma P Jiang, K Sun, YK Tong, SH Cheng, THT Cheng, MMS Heung, J Wong, ... Proceedings of the National Academy of Sciences 115 (46), E10925-E10933, 2018 | 159 | 2018 |
KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas Y Cheng, H Geng, SH Cheng, P Liang, Y Bai, J Li, G Srivastava, MHL Ng, ... Cancer research 70 (16), 6516-6526, 2010 | 146 | 2010 |
Identification and characterization of extrachromosomal circular DNA in maternal plasma STK Sin, P Jiang, J Deng, L Ji, SH Cheng, A Dutta, TY Leung, KCA Chan, ... Proceedings of the National Academy of Sciences 117 (3), 1658-1665, 2020 | 133 | 2020 |
Size-tagged preferred ends in maternal plasma DNA shed light on the production mechanism and show utility in noninvasive prenatal testing K Sun, P Jiang, AIC Wong, YKY Cheng, SH Cheng, H Zhang, KCA Chan, ... Proceedings of the National Academy of Sciences 115 (22), E5106-E5114, 2018 | 129 | 2018 |
Sequencing-based counting and size profiling of plasma Epstein–Barr virus DNA enhance population screening of nasopharyngeal carcinoma WKJ Lam, P Jiang, KCA Chan, SH Cheng, H Zhang, W Peng, OYO Tse, ... Proceedings of the National Academy of Sciences 115 (22), E5115-E5124, 2018 | 127 | 2018 |
Association between HLA‐B*58:01 allele and severe cutaneous adverse reactions with allopurinol in Han Chinese in Hong Kong MLS Chiu, M Hu, MHL Ng, CK Yeung, JCY Chan, MM Chang, SH Cheng, ... British Journal of Dermatology 167 (1), 44-49, 2012 | 119 | 2012 |
Frequent death-associated protein kinase promoter hypermethylation in multiple myeloma MHL Ng, KW To, KW Lo, S Chan, KS Tsang, SH Cheng, HK Ng Clinical Cancer Research 7 (6), 1724-1729, 2001 | 106 | 2001 |