| Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells R Rezaei Araghi, GH Bird, JA Ryan, JM Jenson, M Godes, JR Pritz, ... Proceedings of the National Academy of Sciences 115 (5), E886-E895, 2018 | 88 | 2018 |
| Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence JM Jenson, T Li, F Du, CK Ea, ZJ Chen Nature 616 (7956), 326-331, 2023 | 64 | 2023 |
| Peptide design by optimization on a data-parameterized protein interaction landscape JM Jenson, V Xue, L Stretz, T Mandal, LL Reich, AE Keating Proceedings of the National Academy of Sciences 115 (44), E10342-E10351, 2018 | 63 | 2018 |
| Epistatic mutations in PUMA BH3 drive an alternate binding mode to potently and selectively inhibit anti-apoptotic Bfl-1 JM Jenson, JA Ryan, RA Grant, A Letai, AE Keating Elife 6, e25541, 2017 | 50 | 2017 |
| Tertiary structural motif sequence statistics enable facile prediction and design of peptides that bind anti-apoptotic Bfl-1 and Mcl-1 V Frappier, JM Jenson, J Zhou, G Grigoryan, AE Keating Structure 27 (4), 606-617. e5, 2019 | 43 | 2019 |
| cGAS goes viral: A conserved immune defense system from bacteria to humans JM Jenson, ZJ Chen Molecular Cell 84 (1), 120-130, 2024 | 13 | 2024 |
| Bacteria sting viral invaders J Jenson, ZJ Chen Nature 586 (7829), 363-364, 2020 | 8 | 2020 |
| Ubiquitin-like conjugation by bacterial cgas enhances anti-phage defense ZJ Chen, J Jenson, T Li | 2 | 2022 |
| Peptides selective for Bcl-2 family proteins V Xue, JM Jenson, AE Keating, J Zhou, G Grigoryan US Patent 11,286,299, 2022 | 1 | 2022 |
| Selective Bfl-1 peptides A Keating, JM Jenson US Patent 11,198,715, 2021 | 1 | 2021 |
| Design of selective peptide inhibitors of anti-apoptotic Bfl-1 using experimental screening, structure-based design, and data-driven modeling JM Jenson Massachusetts Institute of Technology, 2018 | | 2018 |
