ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19 JM Leung, CX Yang, A Tam, T Shaipanich, TL Hackett, GK Singhera, ... European Respiratory Journal 55 (5), 2020 | 966 | 2020 |
Induction of epithelial–mesenchymal transition in primary airway epithelial cells from patients with asthma by transforming growth factor-β1 TL Hackett, SM Warner, D Stefanowicz, F Shaheen, DV Pechkovsky, ... American journal of respiratory and critical care medicine 180 (2), 122-133, 2009 | 469 | 2009 |
Lung eQTLs to help reveal the molecular underpinnings of asthma K Hao, Y Bossé, DC Nickle, PD Paré, DS Postma, M Laviolette, ... PLoS genetics 8 (11), e1003029, 2012 | 369 | 2012 |
The contribution of small airway obstruction to the pathogenesis of chronic obstructive pulmonary disease JC Hogg, PD Paré, TL Hackett Physiological reviews 97 (2), 529-552, 2017 | 302 | 2017 |
Airway epithelial regulation of pulmonary immune homeostasis and inflammation TS Hallstrand, TL Hackett, WA Altemeier, G Matute-Bello, PM Hansbro, ... Clinical immunology 151 (1), 1-15, 2014 | 282 | 2014 |
E-cadherin: gatekeeper of airway mucosa and allergic sensitization MC Nawijn, TL Hackett, DS Postma, AJM van Oosterhout, IH Heijink Trends in immunology 32 (6), 248-255, 2011 | 254 | 2011 |
Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution TL Hackett, GK Singhera, F Shaheen, P Hayden, GR Jackson, RG Hegele, ... American journal of respiratory cell and molecular biology 45 (5), 1090-1100, 2011 | 252 | 2011 |
Small airways disease in mild and moderate chronic obstructive pulmonary disease: a cross-sectional study HK Koo, DM Vasilescu, S Booth, A Hsieh, OL Katsamenis, N Fishbane, ... The Lancet Respiratory Medicine 6 (8), 591-602, 2018 | 247 | 2018 |
Epithelial–mesenchymal transition in the pathophysiology of airway remodelling in asthma TL Hackett Current opinion in allergy and clinical immunology 12 (1), 53-59, 2012 | 236 | 2012 |
The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter JA Hirota, SA Hirota, SM Warner, D Stefanowicz, F Shaheen, PL Beck, ... Journal of Allergy and Clinical Immunology 129 (4), 1116-1125. e6, 2012 | 212 | 2012 |
The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation S Post, MC Nawijn, TL Hackett, M Baranowska, R Gras, ... Thorax 67 (6), 488-495, 2012 | 197 | 2012 |
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine CA Brandsma, M Van den Berge, TL Hackett, G Brusselle, W Timens The Journal of pathology 250 (5), 624-635, 2020 | 180 | 2020 |
Toll-like receptor 4-mediated activation of p38 mitogen-activated protein kinase is a determinant of respiratory virus entry and tropism D Marchant, GK Singhera, S Utokaparch, TL Hackett, JH Boyd, Z Luo, X Si, ... Journal of virology 84 (21), 11359-11373, 2010 | 178 | 2010 |
Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study TL Hackett, R Holloway, ST Holgate, JA Warner Respiratory research 9, 1-14, 2008 | 169 | 2008 |
Characterization of side population cells from human airway epithelium TL Hackett, F Shaheen, A Johnson, S Wadsworth, DV Pechkovsky, ... Stem cells 26 (10), 2576-2585, 2008 | 161 | 2008 |
Abnormal M1/M2 macrophage phenotype profiles in the small airway wall and lumen in smokers and chronic obstructive pulmonary disease (COPD) MS Eapen, PM Hansbro, K McAlinden, RY Kim, C Ward, TL Hackett, ... Scientific reports 7 (1), 13392, 2017 | 158 | 2017 |
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK JD Campbell, JE McDonough, JE Zeskind, TL Hackett, DV Pechkovsky, ... Genome medicine 4, 1-16, 2012 | 158 | 2012 |
Imaging collagen in scar tissue: developments in second harmonic generation microscopy for biomedical applications L Mostaço-Guidolin, NL Rosin, TL Hackett International journal of molecular sciences 18 (8), 1772, 2017 | 150 | 2017 |
Airway epithelial barrier function regulates the pathogenesis of allergic asthma IH Heijink, MC Nawijn, TL Hackett Clinical & Experimental Allergy 44 (5), 620-630, 2014 | 139 | 2014 |
DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children D Stefanowicz, TL Hackett, FS Garmaroudi, OP Günther, S Neumann, ... Public Library of Science 7 (9), e44213, 2012 | 133 | 2012 |