The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system T Pelaseyed, JH Bergström, JK Gustafsson, A Ermund, GMH Birchenough, ... Immunological reviews 260 (1), 8-20, 2014 | 1284 | 2014 |
Composition and functional role of the mucus layers in the intestine MEV Johansson, D Ambort, T Pelaseyed, A Schütte, JK Gustafsson, ... Cellular and molecular life sciences 68, 3635-3641, 2011 | 612 | 2011 |
Structure, regulation, and functional diversity of microvilli on the apical domain of epithelial cells C Sauvanet, J Wayt, T Pelaseyed, A Bretscher Annual review of cell and developmental biology 31 (1), 593-621, 2015 | 162 | 2015 |
Regulation of actin-based apical structures on epithelial cells T Pelaseyed, A Bretscher Journal of cell science 131 (20), jcs221853, 2018 | 107 | 2018 |
Membrane mucins of the intestine at a glance T Pelaseyed, GC Hansson Journal of Cell Science 133 (5), jcs240929, 2020 | 102 | 2020 |
Study of mucin turnover in the small intestine by in vivo labeling H Schneider, T Pelaseyed, F Svensson, MEV Johansson Scientific reports 8 (1), 5760, 2018 | 91 | 2018 |
Ezrin activation by LOK phosphorylation involves a PIP2-dependent wedge mechanism T Pelaseyed, R Viswanatha, C Sauvanet, JJ Filter, ML Goldberg, ... Elife 6, e22759, 2017 | 56 | 2017 |
The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine EK Malmberg, T Pelaseyed, ÅC Petersson, UE Seidler, H De Jonge, ... Biochemical Journal 410 (2), 283-289, 2008 | 49 | 2008 |
Unfolding dynamics of the mucin SEA domain probed by force spectroscopy suggest that it acts as a cell‐protective device T Pelaseyed, M Zäch, ÅC Petersson, F Svensson, DGA Johansson, ... The FEBS journal 280 (6), 1491-1501, 2013 | 40 | 2013 |
Murine butyrophilin-like 1 and Btnl6 form heteromeric complexes in small intestinal epithelial cells and promote proliferation of local T lymphocytes C Lebrero-Fernández, JH Bergström, T Pelaseyed, A Bas-Forsberg Frontiers in immunology 7, 1, 2016 | 36 | 2016 |
CFTR anion channel modulates expression of human transmembrane mucin MUC3 through the PDZ protein GOPC T Pelaseyed, GC Hansson Journal of cell science 124 (18), 3074-3083, 2011 | 34 | 2011 |
Carbachol-induced MUC17 endocytosis is concomitant with NHE3 internalization and CFTR membrane recruitment in enterocytes T Pelaseyed, JK Gustafsson, IJ Gustafsson, A Ermund, GC Hansson American Journal of Physiology-Cell Physiology 305 (4), C457-C467, 2013 | 30 | 2013 |
IL-22 promotes the formation of a MUC17 glycocalyx barrier in the postnatal small intestine during weaning E Layunta, S Jäverfelt, B Dolan, L Arike, T Pelaseyed Cell Reports 34 (7), 2021 | 25 | 2021 |
The human transmembrane mucin MUC17 responds to TNFα by increased presentation at the plasma membrane H Schneider, E Berger, B Dolan, B Martinez-Abad, L Arike, T Pelaseyed, ... Biochemical Journal 476 (16), 2281-2295, 2019 | 16 | 2019 |
Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7 T Lang, T Pelaseyed Plos one 17 (10), e0275671, 2022 | 4 | 2022 |
The MYO1B and MYO5B motor proteins and the SNX27 sorting nexin regulate membrane mucin MUC17 trafficking in enterocytes S Jäverfelt, G Hellsén, I Kaji, JR Goldenring, T Pelaseyed bioRxiv, 2023.03. 06.530313, 2023 | 1 | 2023 |
Role of membrane mucin MUC17 in enterocytic barrier dysfunction associated with Crohn’s disease EL Hernandez, S Jäverfelt, T Pelaseyed The Journal of Immunology 206 (1_Supplement), 17.13-17.13, 2021 | 1 | 2021 |
Pulmonary Function Stability After Lung Transplantation is Associated with Decreased Lung Damage Markers in BALF L Arike, K Johansson, A Ermund, M Greer, T Pelaseyed, J Westin, ... The Journal of Heart and Lung Transplantation 43 (4), S185, 2024 | | 2024 |
MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn’s disease E Layunta, S Jäverfelt, FC van de Koolwijk, M Sivertsson, B Dolan, L Arike, ... bioRxiv, 2024 | | 2024 |
Neonatal microbiota colonization drives maturation of primary and secondary goblet cell mediated protection in the pre-weaning colon A Johansson, M Venkita Subramani, B Yilmaz, E Nystrom, E Layunta, ... bioRxiv, 2024.07. 03.601781, 2024 | | 2024 |