Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR‐γ2 transcription factor and TGF‐β/BMP signaling pathways EJ Moerman, K Teng, DA Lipschitz, B Lecka‐Czernik Aging cell 3 (6), 379-389, 2004 | 922 | 2004 |
Thiazolidinedione use and bone loss in older diabetic adults AV Schwartz, DE Sellmeyer, E Vittinghoff, L Palermo, B Lecka-Czernik, ... The Journal of Clinical Endocrinology & Metabolism 91 (9), 3349-3354, 2006 | 637 | 2006 |
Inhibition of Osf2/Cbfa1 expression and terminal osteoblast differentiation by PPARγ2 B Lecka‐Czernik, I Gubrij, EJ Moerman, O Kajkenova, DA Lipschitz, ... Journal of cellular biochemistry 74 (3), 357-371, 1999 | 633 | 1999 |
Divergent Effects of Selective Peroxisome Proliferator-Activated Receptor-γ2 Ligands on Adipocyte Versus Osteoblast Differentiation B Lecka-Czernik, EJ Moerman, DF Grant, JM Lehmann, SC Manolagas, ... Endocrinology 143 (6), 2376-2384, 2002 | 577 | 2002 |
Bone is a target for the antidiabetic compound rosiglitazone SO Rzonca, LJ Suva, D Gaddy, DC Montague, B Lecka-Czernik Endocrinology 145 (1), 401-406, 2004 | 566 | 2004 |
Essential requirement of BMPs‐2/4 for both osteoblast and osteoclast formation in murine bone marrow cultures from adult mice: antagonism by noggin E Abe, M Yamamoto, Y Taguchi, B Lecka‐Czernik, CA O'Brien, ... Journal of Bone and Mineral Research 15 (4), 663-673, 2000 | 420 | 2000 |
Rosiglitazone induces decreases in bone mass and strength that are reminiscent of aged bone OP Lazarenko, SO Rzonca, WR Hogue, FL Swain, LJ Suva, ... Endocrinology 148 (6), 2669-2680, 2007 | 385 | 2007 |
An overview of recent advances in designing orthopedic and craniofacial implants VP Mantripragada, B Lecka‐Czernik, NA Ebraheim, AC Jayasuriya Journal of biomedical materials research Part A 101 (11), 3349-3364, 2013 | 299 | 2013 |
Bone marrow fat has brown adipose tissue characteristics, which are attenuated with aging and diabetes A Krings, S Rahman, S Huang, Y Lu, PJ Czernik, B Lecka-Czernik Bone 50 (2), 546-552, 2012 | 297 | 2012 |
Increased adipogenesis and myelopoiesis in the bone marrow of SAMP6, a murine model of defective osteoblastogenesis and low turnover osteopenia O Kajkenova, B Lecka‐Czernik, I Gubrij, SP Hauser, K Takahashi, ... Journal of Bone and Mineral Research 12 (11), 1772-1779, 1997 | 274 | 1997 |
The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment G Ranganathan, R Unal, I Pokrovskaya, A Yao-Borengasser, ... Journal of lipid research 47 (11), 2444-2450, 2006 | 230 | 2006 |
Bone loss in diabetes: use of antidiabetic thiazolidinediones and secondary osteoporosis B Lecka-Czernik Current osteoporosis reports 8, 178-184, 2010 | 227 | 2010 |
PPARγ2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells KR Shockley, OP Lazarenko, PJ Czernik, CJ Rosen, GA Churchill, ... Journal of cellular biochemistry 106 (2), 232-246, 2009 | 204 | 2009 |
Diabetes, bone and glucose-lowering agents: basic biology B Lecka-Czernik Diabetologia 60 (7), 1163-1169, 2017 | 200 | 2017 |
Activation of an adipogenic program in adult myoblasts with age JM Taylor-Jones, RE McGehee, TA Rando, B Lecka-Czernik, DA Lipschitz, ... Mechanisms of ageing and development 123 (6), 649-661, 2002 | 192 | 2002 |
Skeletal metabolism, fracture risk, and fracture outcomes in type 1 and type 2 diabetes DE Sellmeyer, R Civitelli, LC Hofbauer, S Khosla, B Lecka-Czernik, ... Diabetes 65 (7), 1757-1766, 2016 | 189 | 2016 |
Marrow fat metabolism is linked to the systemic energy metabolism B Lecka-Czernik Bone 50 (2), 534-539, 2012 | 187 | 2012 |
Effects of diabetes drugs on the skeleton C Meier, AV Schwartz, A Egger, B Lecka-Czernik Bone 82, 93-100, 2016 | 186 | 2016 |
Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat OP Lazarenko, SO Rzonca, LJ Suva, B Lecka-Czernik Bone 38 (1), 74-84, 2006 | 184 | 2006 |
A circadian-regulated gene, Nocturnin, promotes adipogenesis by stimulating PPAR-γ nuclear translocation M Kawai, CB Green, B Lecka-Czernik, N Douris, MR Gilbert, S Kojima, ... Proceedings of the National Academy of Sciences 107 (23), 10508-10513, 2010 | 170 | 2010 |