关注
Bob Campbell
Bob Campbell
Redona Therapeutics
在 redonatx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Histone modifications and cancer
JE Audia, RM Campbell
Cold Spring Harbor perspectives in biology 8 (4), a019521, 2016
8612016
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
8382015
The protein kinase Cβ–selective inhibitor, enzastaurin (LY317615. HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon …
JR Graff, AM McNulty, KR Hanna, BW Konicek, RL Lynch, SN Bailey, ...
Cancer research 65 (16), 7462-7469, 2005
5122005
Crystal structure of the human PRMT5: MEP50 complex
S Antonysamy, Z Bonday, RM Campbell, B Doyle, Z Druzina, T Gheyi, ...
Proceedings of the National Academy of Sciences 109 (44), 17960-17965, 2012
3682012
Synthesis and activity of new aryl-and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain
JS Sawyer, BD Anderson, DW Beight, RM Campbell, ML Jones, ...
Journal of medicinal chemistry 46 (19), 3953-3956, 2003
2992003
Synthesis, biological activity and conformational analysis of cyclic GRF analogs
AM Felix, EP HEIMER, CTSO WANG, TJ LAMBROS, A FOURNIER, ...
International journal of peptide and protein research 32 (6), 441-454, 1988
2631988
HLA-DR4-IE chimeric class II transgenic, murine class II-deficient mice are susceptible to experimental allergic encephalomyelitis.
K Ito, HJ Bian, M Molina, J Han, J Magram, E Saar, C Belunis, DR Bolin, ...
The Journal of experimental medicine 183 (6), 2635-2644, 1996
2451996
New assay technologies for high-throughput screening
L Silverman, R Campbell, JR Broach
Current Opinion in Chemical Biology 2 (3), 397-403, 1998
2091998
Kinomics: characterizing the therapeutically validated kinase space
M Vieth, JJ Sutherland, DH Robertson, RM Campbell
Drug discovery today 10 (12), 839-846, 2005
2062005
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of the RB1 Tumor Suppressor Gene
X Gong, J Du, SH Parsons, FF Merzoug, Y Webster, PW Iversen, LC Chio, ...
Cancer discovery 9 (2), 248-263, 2019
1912019
Cancer epigenetics drug discovery and development: the challenge of hitting the mark
RM Campbell, PJ Tummino
The Journal of clinical investigation 124 (1), 64-69, 2014
1852014
Evolution of the growth hormone-releasing factor (GRF) family of peptides.
RM Campbell, CG Scanes
Growth regulation 2 (4), 175-191, 1992
1731992
Sirtuin 1 (SIRT1) the misunderstood HDAC
W Stünkel, RM Campbell
Journal of biomolecular screening 16 (10), 1153-1169, 2011
1712011
Antisense oligonucleotide–mediated MDM4 exon 6 skipping impairs tumor growth
M Dewaele, T Tabaglio, K Willekens, M Bezzi, SX Teo, DHP Low, CM Koh, ...
The Journal of clinical investigation 126 (1), 68-84, 2016
1672016
Synthesis and activity of new aryl-and heteroaryl-substituted 5, 6-dihydro-4H-pyrrolo [1, 2-b] pyrazole inhibitors of the transforming growth factor-β type I receptor kinase domain
JS Sawyer, DW Beight, KS Britt, BD Anderson, RM Campbell, ...
Bioorganic & medicinal chemistry letters 14 (13), 3581-3584, 2004
1662004
Synthesis, Structure− Activity relationship, and biological studies of indolocarbazoles as potent cyclin D1-CDK4 inhibitors
G Zhu, SE Conner, X Zhou, C Shih, T Li, BD Anderson, HB Brooks, ...
Journal of medicinal chemistry 46 (11), 2027-2030, 2003
1582003
Imidazolyl benzimidazoles and imidazo [4, 5-b] pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties
M Mader, A de Dios, C Shih, R Bonjouklian, T Li, W White, BL de Uralde, ...
Bioorganic & medicinal chemistry letters 18 (1), 179-183, 2008
1522008
LLY-283, a potent and selective inhibitor of arginine methyltransferase 5, PRMT5, with antitumor activity
ZQ Bonday, GS Cortez, MJ Grogan, S Antonysamy, K Weichert, ...
ACS medicinal chemistry letters 9 (7), 612-617, 2018
1492018
LLY-507, a cell-active, potent, and selective inhibitor of protein-lysine methyltransferase SMYD2
H Nguyen, A Allali-Hassani, S Antonysamy, S Chang, LH Chen, C Curtis, ...
Journal of Biological Chemistry 290 (22), 13641-13653, 2015
1412015
Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity
RM Campbell, BD Anderson, NA Brooks, HB Brooks, EM Chan, A De Dios, ...
Molecular cancer therapeutics 13 (2), 364-374, 2014
1252014
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