Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA S Yuan, L Peng, JJ Park, Y Hu, SC Devarkar, MB Dong, Q Shen, S Wu, ... Molecular cell 80 (6), 1055-1066. e6, 2020 | 167 | 2020 |
A programmable DNA origami platform for organizing intrinsically disordered nucleoporins within nanopore confinement PDE Fisher, Q Shen, B Akpinar, LK Davis, KKH Chung, D Baddeley, ... ACS nano 12 (2), 1508-1518, 2018 | 100 | 2018 |
Recent advances in DNA origami-engineered nanomaterials and applications P Zhan, A Peil, Q Jiang, D Wang, S Mousavi, Q Xiong, Q Shen, Y Shang, ... Chemical Reviews 123 (7), 3976-4050, 2023 | 71 | 2023 |
Engineering lipid membranes with programmable DNA nanostructures Q Shen, MW Grome, Y Yang, C Lin Advanced biosystems 4 (1), 1900215, 2020 | 48 | 2020 |
Nuclear import of HIV-1 Q Shen, C Wu, C Freniere, TN Tripler, Y Xiong Viruses 13 (11), 2242, 2021 | 34 | 2021 |
A snapshot of HIV-1 capsid–host interactions J Temple, TN Tripler, Q Shen, Y Xiong Current research in structural biology 2, 222-228, 2020 | 28 | 2020 |
Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels Q Shen, Q Feng, C Wu, Q Xiong, T Tian, S Yuan, J Shi, GJ Bedwell, ... Nature structural & molecular biology 30 (4), 425-435, 2023 | 25* | 2023 |
DNA origami post‐processing by CRISPR‐Cas12a Q Xiong, C Xie, Z Zhang, L Liu, JT Powell, Q Shen, C Lin Angewandte Chemie International Edition 59 (10), 3956-3960, 2020 | 23 | 2020 |
Break CDK2/Cyclin E1 interface allosterically with small peptides H Chen, Y Zhao, H Li, D Zhang, Y Huang, Q Shen, R Van Duyne, ... PLoS One 9 (10), e109154, 2014 | 22 | 2014 |
Quantification of biomolecular dynamics inside real and synthetic nuclear pore complexes using time-resolved atomic force microscopy GJ Stanley, B Akpinar, Q Shen, PDE Fisher, CP Lusk, C Lin, ... Acs Nano 13 (7), 7949-7956, 2019 | 20 | 2019 |
Discovery of highly potent TNFα inhibitors using virtual screen Q Shen, J Chen, Q Wang, X Deng, Y Liu, L Lai European Journal of Medicinal Chemistry 85, 119-126, 2014 | 20 | 2014 |
Computational design of helical peptides targeting TNFα. C Zhang, Q Shen, B Tang, L Lai Angewandte Chemie International Edition 52 (42), 2013 | 17 | 2013 |
Functionalized DNA-origami-protein nanopores generate large transmembrane channels with programmable size-selectivity Q Shen, Q Xiong, K Zhou, Q Feng, L Liu, T Tian, C Wu, Y Xiong, TJ Melia, ... Journal of the American Chemical Society 145 (2), 1292-1300, 2022 | 16 | 2022 |
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores Q Shen, S Kumari, C Xu, S Jang, J Shi, RC Burdick, L Levintov, Q Xiong, ... Proceedings of the National Academy of Sciences 120 (13), e2202815120, 2023 | 15 | 2023 |
DNA-origami nanotrap for studying the selective barriers formed by phenylalanine-glycine-rich nucleoporins Q Shen, T Tian, Q Xiong, PD Ellis Fisher, Y Xiong, TJ Melia, CP Lusk, ... Journal of the American Chemical Society 143 (31), 12294-12303, 2021 | 15 | 2021 |
Multifaceted HIV‐1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s Y Hu, KM Knecht, Q Shen, Y Xiong The FEBS journal 288 (11), 3407-3417, 2021 | 12 | 2021 |
Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors X Deng, X Zhang, B Tang, H Liu, Q Shen, Y Liu, L Lai Frontiers in Chemistry 6, 98, 2018 | 12 | 2018 |
De novo design of helical peptides to inhibit tumor necrosis factor-α by disrupting its trimer formation Q Shen, C Zhang, H Liu, Y Liu, J Cao, X Zhang, Y Liang, M Zhao, L Lai MedChemComm 7 (4), 725-729, 2016 | 10 | 2016 |
CLASP2 recognizes tubulins exposed at the microtubule plus-end in a nucleotide state–sensitive manner W Luo, V Demidov, Q Shen, H Girão, M Chakraborty, A Maiorov, ... Science Advances 9 (1), eabq5404, 2023 | 9* | 2023 |
Rational design of TNFα binding proteins based on the de novo designed protein DS119 C Zhu, C Zhang, T Zhang, X Zhang, Q Shen, B Tang, H Liang, L Lai Protein Science 25 (11), 2066-2075, 2016 | 5 | 2016 |