In Vitro and In Vivo Efficacy of Ether Lipid Edelfosine against Leishmania spp. and SbV-Resistant Parasites RE Varela-M, JA Villa-Pulgarin, E Yepes, I Müller, M Modolell, DL Munoz, ... PLoS neglected tropical diseases 6 (4), e1612, 2012 | 70 | 2012 |
Mitochondria and lipid raft-located FOF1-ATP synthase as major therapeutic targets in the antileishmanial and anticancer activities of ether lipid edelfosine JA Villa-Pulgarín, C Gajate, J Botet, A Jimenez, N Justies, RE Varela-M, ... PLoS neglected tropical diseases 11 (8), e0005805, 2017 | 69 | 2017 |
Inhibition of granulomatous inflammation and prophylactic treatment of schistosomiasis with a combination of edelfosine and praziquantel E Yepes, RE Varela-M, J López-Abán, J Rojas-Caraballo, A Muro, ... PLoS Neglected Tropical Diseases 9 (7), e0003893, 2015 | 50 | 2015 |
C-Geranylated flavonoids from Paulownia tomentosa fruits with antimicrobial potential and synergistic activity with antibiotics A Navrátilová, O Nešuta, I Vančatová, A Čížek, RE Varela-M, ... Pharmaceutical Biology 54 (8), 1398-1407, 2016 | 45 | 2016 |
In Vitro and In Vivo Anti-Schistosomal Activity of the Alkylphospholipid Analog Edelfosine E Yepes, RE Varela-M, J Lopez-Aban, ELH Dakir, F Mollinedo, A Muro PLoS One 9 (10), e109431, 2014 | 32 | 2014 |
Polymorphisms in cg2 and pfcrt genes and resistance to chloroquine and other antimalarials in vitro in Plasmodium falciparum isolates from Colombia IJ González, RE Varela, C Murillo, BE Ferro, J Salad, LE Giraldo, MG Zalis, ... Transactions of the Royal Society of Tropical Medicine and Hygiene 97 (3 …, 2003 | 23 | 2003 |
The Akt-like kinase of Leishmania panamensis: As a new molecular target for drug discovery D Tirado-Duarte, M Marín-Villa, R Ochoa, G Blandón-Fuentes, MJ Soares, ... Acta tropica 177, 171-178, 2018 | 17 | 2018 |
The HSP90 inhibitor 17-AAG potentiates the antileishmanial activity of the ether lipid edelfosine RE Varela-M, C Mollinedo-Gajate, A Muro, F Mollinedo Acta tropica 131, 32-36, 2014 | 15 | 2014 |
Biguanide–transition metals complexes as potential drug for hyperglycemia treatment S Villamizar-Delgado, LM Porras-Osorio, O Pineros, J Ellena, N Balcazar, ... RSC advances 10 (38), 22856-22863, 2020 | 12 | 2020 |
Search of Allosteric Inhibitors and Associated Proteins of an AKT-like Kinase from Trypanosoma cruzi R Ochoa, C Rocha-Roa, M Marín-Villa, SM Robledo, RE Varela-M International Journal of Molecular Sciences 19 (12), 3951, 2018 | 9 | 2018 |
Control of invasive alien species: The Giant African snail (Lissachatina fulica) a difficult urban public management challenge M Celis-Ramírez, M Quintero-Angel, RE Varela-M Journal of Environmental Management 322, 116159, 2022 | 8 | 2022 |
Development and use of lipidic nanoparticles loaded with edelfosine and ether phospholipids in antitumoral and antiparasitic therapy A Estella-Hermoso de Mendoza, MJ Blanco-Prieto, MA Campanero, ... P201130433, 2011 | 6 | 2011 |
Identification of Potential Kinase Inhibitors within the PI3K/AKT Pathway of Leishmania Species R Ochoa, A Ortega-Pajares, FA Castello, F Serral, D Fernández Do Porto, ... Biomolecules 11 (7), 1037, 2021 | 5 | 2021 |
Standardization of a multiplex real-time PCR test for the identification of Angiostrongylus cantonensis, A. costaricensis and A. vasorum RE Varela-M, JS Arias, LE Velásquez Biomédica 38 (1), 111-119, 2018 | 5 | 2018 |
In Silico, In Vitro, and Pharmacokinetic Studies of UBMC-4, a Potential Novel Compound for Treating against Trypanosoma cruzi C Bustamante, AF Díez-Mejía, N Arbeláez, MJ Soares, SM Robledo, ... Pathogens 11 (6), 616, 2022 | 2 | 2022 |
Antitumor Activity Provided by N-Alkyl-Nitroimidazole Compounds JA Villa-Pulgarin, CH Salamanca, J Oñate-Garzón, RE Varela-M The Open Medicinal Chemistry Journal 14 (1), 2020 | 1 | 2020 |
AKT-like kinase promotes cell survival during nutritional stress in trypanosomatids AFD Mejía, MM Pedroza, LM Orrego, SAP Muñoz, MC Echeverry, M Rojas, ... bioRxiv 15, 2020 | 1 | 2020 |
GSK-3 kinase a putative therapeutic target in trypanosomatid parasites AP Diaz, CAM Canal, AJ Valdés, JEG Delgado, RE Varela-M Brazilian Journal of Infectious Diseases 28 (2), 103736, 2024 | | 2024 |
AKT-like kinase promotes cell survival during nutritional stress in tripanosomatids AF Díez Mejía, MM Pedroza, LM Orrego, SA Pulido Muñoz, MC Echeverry, ... bioRxiv, 2020.07. 25.218644, 2020 | | 2020 |
Biguanide-transition metals complexes as potential drug for hyperglycemia treatment N Balcázar Morales, S Villamizar Delgado, LM Porras Osorio, O Piñeros, ... Royal Society of Chemistry, 2020 | | 2020 |