Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells H Ellingsgaard, I Hauselmann, B Schuler, AM Habib, LL Baggio, DT Meier, ... Nature medicine 17 (11), 1481-1489, 2011 | 1007 | 2011 |
Inflammation in obesity, diabetes, and related disorders TV Rohm, DT Meier, JM Olefsky, MY Donath Immunity 55 (1), 31-55, 2022 | 711 | 2022 |
Free fatty acids induce a proinflammatory response in islets via the abundantly expressed interleukin-1 receptor I M Böni-Schnetzler, S Boller, S Debray, K Bouzakri, DT Meier, R Prazak, ... Endocrinology 150 (12), 5218-5229, 2009 | 420 | 2009 |
Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation E Dror, E Dalmas, DT Meier, S Wueest, J Thévenet, C Thienel, K Timper, ... Nature immunology 18 (3), 283-292, 2017 | 373 | 2017 |
Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet JA Ehses, DT Meier, S Wueest, J Rytka, S Boller, PY Wielinga, ... Diabetologia 53, 1795-1806, 2010 | 272 | 2010 |
Low-and high-density lipoproteins modulate function, apoptosis, and proliferation of primary human and murine pancreatic β-cells S Rutti, JA Ehses, RA Sibler, R Prazak, L Rohrer, S Georgopoulos, ... Endocrinology 150 (10), 4521-4530, 2009 | 256 | 2009 |
Islet inflammation in type 2 diabetes M Böni-Schnetzler, DT Meier Seminars in immunopathology 41, 501-513, 2019 | 171 | 2019 |
Identification of a SIRT1 mutation in a family with type 1 diabetes A Biason-Lauber, M Böni-Schnetzler, BP Hubbard, K Bouzakri, A Brunner, ... Cell metabolism 17 (3), 448-455, 2013 | 134 | 2013 |
Pancreatic α cell-derived glucagon-related peptides are required for β cell adaptation and glucose homeostasis S Traub, DT Meier, F Schulze, E Dror, TM Nordmann, N Goetz, N Koch, ... Cell reports 18 (13), 3192-3203, 2017 | 107 | 2017 |
Inflammation in the pathophysiology and therapy of cardiometabolic disease MY Donath, DT Meier, M Böni-Schnetzler Endocrine reviews 40 (4), 1080-1091, 2019 | 105 | 2019 |
β cell-specific deletion of the IL-1 receptor antagonist impairs β cell proliferation and insulin secretion M Böni-Schnetzler, SP Häuselmann, E Dalmas, DT Meier, C Thienel, ... Cell reports 22 (7), 1774-1786, 2018 | 81 | 2018 |
Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice DT Meier, M Morcos, T Samarasekera, S Zraika, RL Hull, SE Kahn Diabetologia 57, 1884-1888, 2014 | 78 | 2014 |
One year of sitagliptin treatment protects against islet amyloid-associated β-cell loss and does not induce pancreatitis or pancreatic neoplasia in mice K Aston-Mourney, SL Subramanian, S Zraika, T Samarasekera, DT Meier, ... American Journal of Physiology-Endocrinology and Metabolism 305 (4), E475-E484, 2013 | 54 | 2013 |
The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets DT Meier, L Entrup, AT Templin, MF Hogan, M Mellati, S Zraika, RL Hull, ... Diabetologia 59 (10), 2166-2171, 2016 | 38 | 2016 |
The cephalic phase of insulin release is modulated by IL-1β SJ Wiedemann, K Trimigliozzi, E Dror, DT Meier, JA Molina-Tijeras, ... Cell metabolism 34 (7), 991-1003. e6, 2022 | 24 | 2022 |
Apoptosis repressor with caspase recruitment domain ameliorates amyloid-induced β-cell apoptosis and JNK pathway activation AT Templin, T Samarasekera, DT Meier, MF Hogan, M Mellati, MT Crow, ... Diabetes 66 (10), 2636-2645, 2017 | 23 | 2017 |
Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity TV Rohm, L Keller, AJT Bosch, S AlAsfoor, Z Baumann, A Thomas, ... Communications biology 5 (1), 370, 2022 | 21 | 2022 |
Inhibition of IL-1beta improves glycaemia in a mouse model for gestational diabetes F Schulze, J Wehner, DV Kratschmar, V Makshana, DT Meier, ... Scientific reports 10 (1), 3035, 2020 | 20 | 2020 |
Determination of optimal sample size for quantification of β-cell area, amyloid area and β-cell apoptosis in isolated islets DT Meier, L Entrup, AT Templin, MF Hogan, T Samarasekera, S Zraika, ... Journal of Histochemistry & Cytochemistry 63 (8), 663-673, 2015 | 20 | 2015 |
Matrix metalloproteinase-9 protects islets from amyloid-induced toxicity DT Meier, LH Tu, S Zraika, MF Hogan, AT Templin, RL Hull, DP Raleigh, ... Journal of Biological Chemistry 290 (51), 30475-30485, 2015 | 17 | 2015 |