The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity M Dudek, N Gossan, N Yang, HJ Im, JPD Ruckshanthi, H Yoshitane, X Li, ... The Journal of clinical investigation 126 (1), 365-376, 2016 | 187 | 2016 |
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration M Dudek, N Yang, JPD Ruckshanthi, J Williams, E Borysiewicz, P Wang, ... Annals of the rheumatic diseases 76 (3), 576-584, 2017 | 145 | 2017 |
Running on time: the role of circadian clocks in the musculoskeletal system M Dudek, QJ Meng Biochemical journal 463 (1), 1-8, 2014 | 112 | 2014 |
Catabolic cytokines disrupt the circadian clock and the expression of clock-controlled genes in cartilage via an NFкB-dependent pathway B Guo, N Yang, E Borysiewicz, M Dudek, JL Williams, J Li, ES Maywood, ... Osteoarthritis and cartilage 23 (11), 1981-1988, 2015 | 92 | 2015 |
Tissue physiology revolving around the clock: circadian rhythms as exemplified by the intervertebral disc H Morris, CF Gonçalves, M Dudek, J Hoyland, QJ Meng Annals of the rheumatic diseases 80 (7), 828-839, 2021 | 34 | 2021 |
Quantitative live imaging of Venus:: BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator N Yang, NJ Smyllie, H Morris, CF Gonçalves, M Dudek, DRJ Pathiranage, ... PLoS genetics 16 (4), e1008729, 2020 | 28 | 2020 |
Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature 623 (7988), 842-852, 2023 | 27 | 2023 |
Circadian time series proteomics reveals daily dynamics in cartilage physiology M Dudek, C Angelucci, D Pathiranage, P Wang, V Mallikarjun, C Lawless, ... Osteoarthritis and cartilage 29 (5), 739-749, 2021 | 23 | 2021 |
Restoring the dampened expression of the core clock molecule BMAL1 protects against compression-induced intervertebral disc degeneration D Wang, P Peng, M Dudek, X Hu, X Xu, Q Shang, D Wang, H Jia, H Wang, ... Bone research 10 (1), 20, 2022 | 15 | 2022 |
The circadian clock and extracellular matrix homeostasis in aging and age-related diseases M Dudek, J Swift, QJ Meng American Journal of Physiology-Cell Physiology 325 (1), C52-C59, 2023 | 12 | 2023 |
Synthetic gene circuits for preventing disruption of the circadian clock due to interleukin-1–induced inflammation L Pferdehirt, AR Damato, M Dudek, QJ Meng, ED Herzog, F Guilak Science Advances 8 (21), eabj8892, 2022 | 10 | 2022 |
The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc M Dudek, H Morris, N Rogers, DRJ Pathiranage, SS Raj, D Chan, ... Matrix Biology 122, 1-9, 2023 | 9 | 2023 |
Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks M Dudek, DRJ Pathiranage, B Bano-Otalora, A Paszek, N Rogers, ... Nature communications 14 (1), 7237, 2023 | 4 | 2023 |
Vimentin intermediate filaments provide structural stability to the mammalian Golgi complex T Vitali, R Sanchez-Alvarez, TM Witkos, I Bantounas, MFA Cutiongco, ... Journal of Cell Science 136 (20), 2023 | 3 | 2023 |
Author Correction: Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature, 1-1, 2024 | 1 | 2024 |
Investigations of the Ufm1 pathway and its association with a familial form of hip dysplasia M Dudek PQDT-UK & Ireland, 2013 | 1 | 2013 |
MECHANICAL LOADING AND HYPEROSMOLARITY AS A DAILY RESETTING TIME CUE FOR SKELETAL CIRCADIAN CLOCKS M Dudek, J Hoyland, QJ Meng Osteoarthritis and Cartilage 32 (6), 814, 2024 | | 2024 |
Modulation of circadian rhythms in articular cartilage by heat pulses CF Gonçalves, M Dudek, DRJ Pathiranage, A Paszek, Z El-Houni, S Li, ... bioRxiv, 2024.01. 26.577368, 2024 | | 2024 |
Circadian clocks, extracellular matrix and endochondral ossification in the intervertebral disc M Dudek, H Morris, Y Lu, KE Kadler, JA Hoyland, QJ Meng INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY 104 (2), A17-A17, 2023 | | 2023 |
The Ufm1 system is upregulated by ER stress during osteogenic differentiation M Dudek, GA Wallis bioRxiv, 720490, 2019 | | 2019 |