Neuronal ensembles sufficient for recovery sleep and the sedative actions of α2 adrenergic agonists Z Zhang, V Ferretti, İ Güntan, A Moro, EA Steinberg, Z Ye, AY Zecharia, ... Nature neuroscience 18 (4), 553-561, 2015 | 267 | 2015 |
GABA and glutamate neurons in the VTA regulate sleep and wakefulness X Yu, W Li, Y Ma, K Tossell, JJ Harris, EC Harding, W Ba, G Miracca, ... Nature neuroscience 22 (1), 106-119, 2019 | 234 | 2019 |
Wakefulness is governed by GABA and histamine cotransmission X Yu, Z Ye, CM Houston, AY Zecharia, Y Ma, Z Zhang, DS Uygun, ... Neuron 87 (1), 164-178, 2015 | 179 | 2015 |
Protective effects of chlorogenic acid on acute hepatotoxicity induced by lipopolysaccharide in mice Y Xu, J Chen, X Yu, W Tao, F Jiang, Z Yin, C Liu Inflammation Research 59, 871-877, 2010 | 134 | 2010 |
Egr‐1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice X Yu, N Shen, ML Zhang, FY Pan, C Wang, WP Jia, C Liu, Q Gao, X Gao, ... The EMBO journal 30 (18), 3754-3765, 2011 | 115 | 2011 |
A neuronal hub binding sleep initiation and body cooling in response to a warm external stimulus EC Harding, X Yu, A Miao, N Andrews, Y Ma, Z Ye, L Lignos, G Miracca, ... Current Biology 28 (14), 2263-2273. e4, 2018 | 112 | 2018 |
GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep–wake switch or propofol-induced loss of consciousness AY Zecharia, X Yu, T Götz, Z Ye, DR Carr, P Wulff, B Bettler, AL Vyssotski, ... Journal of Neuroscience 32 (38), 13062-13075, 2012 | 102 | 2012 |
An early response transcription factor, Egr-1, enhances insulin resistance in type 2 diabetes with chronic hyperinsulinism N Shen, X Yu, FY Pan, X Gao, B Xue, CJ Li Journal of Biological Chemistry 286 (16), 14508-14515, 2011 | 102 | 2011 |
Circadian factor BMAL1 in histaminergic neurons regulates sleep architecture X Yu, A Zecharia, Z Zhang, Q Yang, R Yustos, P Jager, AL Vyssotski, ... Current Biology 24 (23), 2838-2844, 2014 | 95 | 2014 |
Celastrol attenuates hypertension-induced inflammation and oxidative stress in vascular smooth muscle cells via induction of heme oxygenase-1 X Yu, W Tao, F Jiang, C Li, J Lin, C Liu American journal of hypertension 23 (8), 895-903, 2010 | 94 | 2010 |
Galanin neurons unite sleep homeostasis and α2-adrenergic sedation Y Ma, G Miracca, X Yu, EC Harding, A Miao, R Yustos, AL Vyssotski, ... Current Biology 29 (19), 3315-3322. e3, 2019 | 87 | 2019 |
GABA receptors and the pharmacology of sleep W Wisden, X Yu, NP Franks Sleep-wake neurobiology and pharmacology, 279-304, 2019 | 87 | 2019 |
Excitatory pathways from the lateral habenula enable propofol-induced sedation C Gelegen, G Miracca, MZ Ran, EC Harding, Z Ye, X Yu, K Tossell, ... Current Biology 28 (4), 580-587. e5, 2018 | 81 | 2018 |
A specific circuit in the midbrain detects stress and induces restorative sleep X Yu, G Zhao, D Wang, S Wang, R Li, A Li, H Wang, M Nollet, YY Chun, ... Science 377 (6601), 63-72, 2022 | 61 | 2022 |
Sleep and sedative states induced by targeting the histamine and noradrenergic systems X Yu, NP Franks, W Wisden Frontiers in Neural Circuits 12, 4, 2018 | 58 | 2018 |
Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus P Jager, Z Ye, X Yu, L Zagoraiou, HT Prekop, J Partanen, TM Jessell, ... Nature communications 7 (1), 13579, 2016 | 52 | 2016 |
Bottom-up versus top-down induction of sleep by zolpidem acting on histaminergic and neocortex neurons DS Uygun, Z Ye, AY Zecharia, EC Harding, X Yu, R Yustos, AL Vyssotski, ... Journal of Neuroscience 36 (44), 11171-11184, 2016 | 50 | 2016 |
Dysfunction of ventral tegmental area GABA neurons causes mania-like behavior X Yu, W Ba, G Zhao, Y Ma, EC Harding, L Yin, D Wang, H Li, P Zhang, ... Molecular psychiatry 26 (9), 5213-5228, 2021 | 48 | 2021 |
The constitutive activation of Egr-1/C/EBPa mediates the development of type 2 diabetes mellitus by enhancing hepatic gluconeogenesis N Shen, S Jiang, JM Lu, X Yu, SS Lai, JZ Zhang, JL Zhang, WW Tao, ... The American journal of pathology 185 (2), 513-523, 2015 | 28 | 2015 |
Genetic lesioning of histamine neurons increases sleep–wake fragmentation and reveals their contribution to modafinil-induced wakefulness X Yu, Y Ma, EC Harding, R Yustos, AL Vyssotski, NP Franks, W Wisden Sleep 42 (5), zsz031, 2019 | 26 | 2019 |