Unnatural amino acid photo-crosslinking of the IKs channel complex demonstrates a KCNE1:KCNQ1 stoichiometry of up to 4:4 CI Murray, M Westhoff, J Eldstrom, E Thompson, R Emes, D Fedida Elife 5, e11815, 2016 | 86 | 2016 |
β-Adrenergic control of sarcolemmal CaV1.2 abundance by small GTPase Rab proteins SG Del Villar, TL Voelker, M Westhoff, GR Reddy, HC Spooner, ... Proceedings of the National Academy of Sciences 118 (7), e2017937118, 2021 | 40 | 2021 |
IKs ion-channel pore conductance can result from individual voltage sensor movements M Westhoff, J Eldstrom, CI Murray, E Thompson, D Fedida Proceedings of the National Academy of Sciences 116 (16), 7879-7888, 2019 | 37 | 2019 |
cAMP-dependent regulation of IKs single-channel kinetics E Thompson, J Eldstrom, M Westhoff, D McAfee, E Balse, D Fedida Journal of General Physiology 149 (8), 781-798, 2017 | 32 | 2017 |
Mechanisms and Regulation of Cardiac CaV1.2 Trafficking M Westhoff, RE Dixon International Journal of Molecular Sciences 22 (11), 5927, 2021 | 24 | 2021 |
Photo-cross-linking of IKs demonstrates state-dependent interactions between KCNE1 and KCNQ1 M Westhoff, CI Murray, J Eldstrom, D Fedida Biophysical journal 113 (2), 415-425, 2017 | 24 | 2017 |
The IKs channel response to cAMP is modulated by the KCNE1: KCNQ1 stoichiometry E Thompson, J Eldstrom, M Westhoff, D McAfee, D Fedida Biophysical Journal 115 (9), 1731-1740, 2018 | 12 | 2018 |
Acute phosphatidylinositol 4,5 bisphosphate depletion destabilizes sarcolemmal expression of cardiac L-type Ca2+ channel CaV1.2 TL Voelker, SG Del Villar, M Westhoff, AD Costa, AM Coleman, JW Hell, ... Proceedings of the National Academy of Sciences 120 (14), e2221242120, 2023 | 6 | 2023 |
BIN1 knockdown rescues systolic dysfunction in aging male mouse hearts M Westhoff, SG Del Villar, TL Voelker, PN Thai, HC Spooner, AD Costa, ... nature communications 15 (1), 3528, 2024 | 1 | 2024 |
Restoration of β-adrenergic responsivity in the aging heart SG del Villar, M Westhoff, TL Voelker, EJ Dickson, RE Dixon bioRxiv, 2022 | 1 | 2022 |
Evaluating sequential and allosteric activation models in IKs channels with mutated voltage sensors D Fedida, D Sastre, Y Dou, M Westhoff, J Eldstrom Journal of General Physiology 156 (3), e202313465, 2024 | | 2024 |
Chronic angiotensin II signaling drives sustained PIP2 deficits and altered sarcolemmal Cav1. 2 expression and function in cardiomyocytes TL Voelker, SG Del Villar, MF Westhoff, EJ Dickson, RE Dixon Biophysical Journal 122 (3), 254a, 2023 | | 2023 |
Restoration of β-adrenergic responsivity in the aging heart M Westhoff, SG Del Villar, TL Voelker, PN Thai, N Chiamvimonvat, ... Biophysical Journal 122 (3), 375a, 2023 | | 2023 |
BIN1 is essential for β-adrenergic regulation of cardiac function SG Del Villar, DW Ito, MF Westhoff, EJ Dickson, RE Dixon Biophysical Journal 122 (3), 165a-166a, 2023 | | 2023 |
14-3-3 regulates cardiac CaV1. 2 clustering, expression, and trafficking H Spooner, MF Westhoff, H Ibrahimkhail, A Yarovaya, EJ Dickson, ... Biophysical Journal 122 (3), 378a, 2023 | | 2023 |
Acute PI (4, 5) P2 regulation of Cav1. 2 l-type Ca2+ channels in the heart TL Voelker, MF Westhoff, AM Coleman, MC Horne, J Hell, EJ Dickson, ... Biophysical Journal 121 (3), 12a, 2022 | | 2022 |
Altered Cav1. 2 trafficking contributes to β-adrenergic receptor hypo-responsivity in the aging myocardium M Westhoff, SG del Villar, TL Voelker, EJ Dickson, RE Dixon Biophysical Journal 121 (3), 98a, 2022 | | 2022 |
IKS Ion-Channel Pore Conductance Can Result from Individual Voltage Sensor Movements D Fedida, MF Westhoff, JR Eldstrom, CI Murray, E Thompson Biophysical Journal 118 (3), 332a, 2020 | | 2020 |
Understanding the interactions that occur between KCNE1 and KCNQ1: stoichiometry, gating and dynamic movements MFE Westhoff University of British Columbia, 2019 | | 2019 |
Effect of Camp When Varying the Number of KCNE1 Subunits in the IKs Complex E Thompson, J Eldstrom, M Westhoff, D McAfee, D Fedida Biophysical Journal 114 (3), 121a, 2018 | | 2018 |