| Evolutionary dynamics of gene and isoform regulation in Mammalian tissues J Merkin, C Russell, P Chen, CB Burge Science 338 (6114), 1593-1599, 2012 | 1021 | 2012 |
| Single-cell RNA counting at allele and isoform resolution using Smart-seq3 M Hagemann-Jensen, C Ziegenhain, P Chen, D Ramsköld, GJ Hendriks, ... Nature biotechnology 38 (6), 708-714, 2020 | 510 | 2020 |
| Large-scale data integration framework provides a comprehensive view on glioblastoma multiforme K Ovaska, M Laakso, S Haapa-Paananen, R Louhimo, P Chen, ... Genome medicine 2, 1-12, 2010 | 229 | 2010 |
| A subset of Kupffer cells regulates metabolism through the expression of CD36 C Blériot, E Barreby, G Dunsmore, R Ballaire, S Chakarov, X Ficht, ... Immunity 54 (9), 2101-2116. e6, 2021 | 124 | 2021 |
| Macrophage functional diversity in NAFLD—more than inflammation E Barreby, P Chen, M Aouadi Nature Reviews Endocrinology 18 (8), 461-472, 2022 | 100 | 2022 |
| Obesity and hyperinsulinemia drive adipocytes to activate a cell cycle program and senesce Q Li, CE Hagberg, H Silva Cascales, S Lang, MT Hyvönen, F Salehzadeh, ... Nature medicine 27 (11), 1941-1953, 2021 | 100 | 2021 |
| Repression of TIF1γ by SOX2 promotes TGF-β-induced epithelial–mesenchymal transition in non-small-cell lung cancer ZHT Wang L, Yang H, Lei Z, Zhao J, Chen Y, Chen P, Li C, Zeng Y, Liu Z, Liu X Oncogene, 2015 | 79* | 2015 |
| Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes B He, P Chen, S Zambrano, D Dabaghie, Y Hu, K Möller-Hackbarth, ... Nature Communications 12 (1), 2141, 2021 | 65 | 2021 |
| Netrin-4 promotes glioblastoma cell proliferation through integrin β4 signaling Y Hu, I Ylivinkka, P Chen, L Li, S Hautaniemi, TA Nyman, J Keski-Oja, ... Neoplasia 14 (3), 219-IN23, 2012 | 57 | 2012 |
| Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance V Azzimato, J Jager, P Chen, C Morgantini, L Levi, E Barreby, A Sulen, ... Science translational medicine 12 (532), eaaw9709, 2020 | 51 | 2020 |
| Functional profiling of precursor MicroRNAs identifies MicroRNAs essential for glioma proliferation S Haapa-Paananen, P Chen, K Hellström, P Kohonen, S Hautaniemi, ... PloS one 8 (4), e60930, 2013 | 50 | 2013 |
| ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors K Kaipio, P Chen, P Roering, K Huhtinen, P Mikkonen, P Östling, ... The Journal of pathology 250 (2), 159-169, 2020 | 45 | 2020 |
| Origins and impacts of new mammalian exons JJ Merkin, P Chen, MS Alexis, SK Hautaniemi, CB Burge Cell Reports 10 (12), 1992-2005, 2015 | 45 | 2015 |
| Comprehensive exon array data processing method for quantitative analysis of alternative spliced variants P Chen, T Lepikhova, Y Hu, O Monni, S Hautaniemi Nucleic acids research 39 (18), e123-e123, 2011 | 45 | 2011 |
| Identification of prognostic groups in high-grade serous ovarian cancer treated with platinum–taxane chemotherapy P Chen, K Huhtinen, K Kaipio, P Mikkonen, V Aittomäki, R Lindell, ... Cancer research 75 (15), 2987-2998, 2015 | 42 | 2015 |
| SePIA: RNA and small RNA sequence processing, integration, and analysis K Icay, P Chen, A Cervera, V Rantanen, R Lehtonen, S Hautaniemi BioData mining 9, 1-18, 2016 | 41 | 2016 |
| Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel M Tambe, S Pruikkonen, J Mäki-Jouppila, P Chen, BV Elgaaen, ... Oncotarget 7 (11), 12267, 2016 | 41 | 2016 |
| Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity V Azzimato, P Chen, E Barreby, C Morgantini, L Levi, A Vankova, J Jager, ... Gastroenterology 161 (6), 1982-1997. e11, 2021 | 38 | 2021 |
| SjTPdb: integrated transcriptome and proteome database and analysis platform for Schistosoma japonicum F Liu, P Chen, SJ Cui, ZQ Wang, ZG Han BMC genomics 9, 1-11, 2008 | 36 | 2008 |
| MYC-induced miR-203b-3p and miR-203a-3p control Bcl-xL expression and paclitaxel sensitivity in tumor cells S Aakko, AH Straume, EE Birkeland, P Chen, X Qiao, MJ Kallio Translational oncology 12 (1), 170-179, 2019 | 35 | 2019 |
