| High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... Science translational medicine 9 (377), eaaf2584, 2017 | 362 | 2017 |
| Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... Cell reports 32 (3), 2020 | 266 | 2020 |
| Use of human induced pluripotent stem cell–derived cardiomyocytes to assess drug cardiotoxicity A Sharma, WL McKeithan, R Serrano, T Kitani, PW Burridge, ... Nature protocols 13 (12), 3018-3041, 2018 | 142 | 2018 |
| Engineering synthetic morphogen systems that can program multicellular patterning S Toda, WL McKeithan, TJ Hakkinen, P Lopez, OD Klein, WA Lim Science 370 (6514), 327-331, 2020 | 115 | 2020 |
| A premature termination codon mutation in MYBPC3 causes hypertrophic cardiomyopathy via chronic activation of nonsense-mediated decay T Seeger, R Shrestha, CK Lam, C Chen, WL McKeithan, E Lau, ... Circulation 139 (6), 799-811, 2019 | 114 | 2019 |
| An automated platform for assessment of congenital and drug-induced arrhythmia with hiPSC-derived cardiomyocytes WL McKeithan, A Savchenko, MS Yu, F Cerignoli, AAN Bruyneel, JH Price, ... Frontiers in physiology 8, 766, 2017 | 80 | 2017 |
| Id genes are essential for early heart formation TJ Cunningham, SY Michael, WL McKeithan, S Spiering, F Carrette, ... Genes & development 31 (13), 1325-1338, 2017 | 75 | 2017 |
| Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis AR Colas, WL McKeithan, TJ Cunningham, PJ Bushway, LX Garmire, ... Genes & development 26 (23), 2567-2579, 2012 | 73 | 2012 |
| Programming multicellular assembly with synthetic cell adhesion molecules AJ Stevens, AR Harris, J Gerdts, KH Kim, C Trentesaux, JT Ramirez, ... Nature 614 (7946), 144-152, 2023 | 69 | 2023 |
| Reengineering an antiarrhythmic drug using patient hiPSC cardiomyocytes to improve therapeutic potential and reduce toxicity WL McKeithan, DAM Feyen, AAN Bruyneel, KJ Okolotowicz, DA Ryan, ... Cell Stem Cell 27 (5), 813-821. e6, 2020 | 43 | 2020 |
| Will iPSC-cardiomyocytes revolutionize the discovery of drugs for heart disease? AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola Current opinion in pharmacology 42, 55-61, 2018 | 25 | 2018 |
| High-throughput screening of tyrosine kinase inhibitor cardiotoxicity with human induced pluripotent stem cells. Sci Transl Med 9 A Sharma, PW Burridge, WL McKeithan, R Serrano, P Shukla, N Sayed, ... | 21 | 2017 |
| CRISPR/Cas9-based targeting of fluorescent reporters to human iPSCs to isolate atrial and ventricular-specific cardiomyocytes O Chirikian, WR Goodyer, E Dzilic, V Serpooshan, JW Buikema, ... Scientific reports 11 (1), 3026, 2021 | 20 | 2021 |
| Metabolic maturation media improve physiological function of human iPSC-derived cardiomyocytes. Cell Rep 32: 107925 DAM Feyen, WL McKeithan, AAN Bruyneel, S Spiering, L Hörmann, ... | 13 | 2020 |
| Using iPSC models to probe regulation of cardiac ion channel function AAN Bruyneel, WL McKeithan, DAM Feyen, M Mercola Current Cardiology Reports 20, 1-12, 2018 | 9 | 2018 |
| Antiarrhythmic hit to lead refinement in a dish using patient-derived iPSC cardiomyocytes JR Cashman, D Ryan, WL McKeithan, K Okolotowicz, J Gomez-Galeno, ... Journal of Medicinal Chemistry 64 (9), 5384-5403, 2021 | 8 | 2021 |
| Serum‐Free Generation of Multipotent Mesoderm (Kdr+) Progenitor Cells in Mouse Embryonic Stem Cells for Functional Genomics Screening WL McKeithan, AR Colas, PJ Bushway, S Ray, M Mercola Current protocols in stem cell biology 23 (1), 1F. 13.1-1F. 13.13, 2012 | 8 | 2012 |
| Human iPSC-derived cardiomyocytes and pyridyl-phenyl mexiletine analogs M Johnson, J Gomez-Galeno, D Ryan, K Okolotowicz, WL McKeithan, ... Bioorganic & Medicinal Chemistry Letters 46, 128162, 2021 | 5 | 2021 |
| Small-molecule probe reveals a kinase cascade that links stress signaling to TCF/LEF and Wnt responsiveness J Cheng, M Tsuda, K Okolotowicz, M Dwyer, PJ Bushway, AR Colas, ... Cell chemical biology 28 (5), 625-635. e5, 2021 | 5 | 2021 |
| Human‐induced pluripotent stem cell‐derived cardiomyocytes: Cardiovascular properties and metabolism and pharmacokinetics of deuterated mexiletine analogs J Gomez‐Galeno, K Okolotowicz, M Johnson, WL McKeithan, M Mercola, ... Pharmacology Research & Perspectives 9 (4), e00828, 2021 | 4 | 2021 |
