Neoantigen-directed immune escape in lung cancer evolution R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ... Nature 567 (7749), 479-485, 2019 | 767 | 2019 |
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 548 | 2018 |
Cancer-associated fibroblasts induce antigen-specific deletion of CD8+ T Cells to protect tumour cells MA Lakins, E Ghorani, H Munir, CP Martins, JD Shields Nature communications 9 (1), 948, 2018 | 487 | 2018 |
Pan-cancer deconvolution of tumour composition using DNA methylation A Chakravarthy, A Furness, K Joshi, E Ghorani, K Ford, MJ Ward, EV King, ... Nature communications 9 (1), 3220, 2018 | 258 | 2018 |
Tissue-resident memory CD8+ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells E Menares, F Gálvez-Cancino, P Cáceres-Morgado, E Ghorani, E López, ... Nature communications 10 (1), 4401, 2019 | 187 | 2019 |
Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia E Ghorani, B Kaur, RA Fisher, D Short, U Joneborg, JW Carlson, A Akarca, ... The Lancet 390 (10110), 2343-2345, 2017 | 187 | 2017 |
Regulatory T cells restrain interleukin-2-and Blimp-1-dependent acquisition of cytotoxic function by CD4+ T cells A Śledzińska, MV de Mucha, K Bergerhoff, A Hotblack, DF Demane, ... Immunity 52 (1), 151-166. e6, 2020 | 174 | 2020 |
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ... Nature medicine 25 (10), 1549-1559, 2019 | 171 | 2019 |
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ... Cancer cell 39 (11), 1497-1518. e11, 2021 | 163 | 2021 |
CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity I Solomon, M Amann, A Goubier, F Arce Vargas, D Zervas, C Qing, ... Nature cancer 1 (12), 1153-1166, 2020 | 126 | 2020 |
Differential binding affinity of mutated peptides for MHC class I is a predictor of survival in advanced lung cancer and melanoma E Ghorani, R Rosenthal, N McGranahan, JL Reading, M Lynch, KS Peggs, ... Annals of oncology 29 (1), 271-279, 2018 | 124 | 2018 |
Intraplacental choriocarcinoma: systematic review and management guidance L Jiao, E Ghorani, NJ Sebire, MJ Seckl Gynecologic Oncology 141 (3), 624-631, 2016 | 88 | 2016 |
The T cell differentiation landscape is shaped by tumour mutations in lung cancer E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ... Nature cancer 1 (5), 546-561, 2020 | 87 | 2020 |
Cell communication with the neural plate is required for induction of neural markers by BMP inhibition: evidence for homeogenetic induction and implications for Xenopus animal … C Linker, I De Almeida, C Papanayotou, M Stower, V Sabado, E Ghorani, ... Developmental biology 327 (2), 478-486, 2009 | 61 | 2009 |
Safety and efficacy of modified FOLFIRINOX for advanced pancreatic adenocarcinoma: a UK single-centre experience E Ghorani, HH Wong, C Hewitt, J Calder, P Corrie, B Basu Oncology 89 (5), 281-287, 2015 | 54 | 2015 |
Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment YNS Wong, K Joshi, P Khetrapal, M Ismail, JL Reading, MW Sunderland, ... Journal of Experimental Medicine 215 (11), 2748-2759, 2018 | 53 | 2018 |
When to stop human chorionic gonadotrophin (hCG) surveillance after treatment with chemotherapy for gestational trophoblastic neoplasia (GTN): a national analysis on over 4,000 … K Balachandran, A Salawu, E Ghorani, B Kaur, NJ Sebire, D Short, ... Gynecologic oncology 155 (1), 8-12, 2019 | 52 | 2019 |
Marrow-infiltrating regulatory T cells correlate with the presence of dysfunctional CD4+ PD-1+ cells and inferior survival in patients with newly diagnosed multiple myeloma N Alrasheed, L Lee, E Ghorani, JY Henry, L Conde, M Chin, ... Clinical Cancer Research 26 (13), 3443-3454, 2020 | 48 | 2020 |
Predictors for single-agent resistance in FIGO score 5 or 6 gestational trophoblastic neoplasia: a multicentre, retrospective, cohort study A Braga, G Paiva, E Ghorani, F Freitas, LGC Velarde, B Kaur, N Unsworth, ... The Lancet Oncology 22 (8), 1188-1198, 2021 | 44 | 2021 |
Differential cytopathology and kinetics of measles oncolysis in two primary B-cell malignancies provides mechanistic insights B Patel, A Dey, E Ghorani, S Kumar, Y Malam, L Rai, AJ Steele, ... Molecular Therapy 19 (6), 1034-1040, 2011 | 29 | 2011 |