Coactivator condensation at super-enhancers links phase separation and gene control BR Sabari, A Dall’Agnese, A Boija, IA Klein, EL Coffey, K Shrinivas, ... Science 361 (6400), eaar3958, 2018 | 1945 | 2018 |
Transcription factors activate genes through the phase-separation capacity of their activation domains A Boija, IA Klein, BR Sabari, A Dall’Agnese, EL Coffey, AV Zamudio, ... Cell 175 (7), 1842-1855. e16, 2018 | 1398 | 2018 |
Pol II phosphorylation regulates a switch between transcriptional and splicing condensates YE Guo, JC Manteiga, JE Henninger, BR Sabari, A Dall’Agnese, ... Nature 572 (7770), 543-548, 2019 | 527 | 2019 |
Partitioning of cancer therapeutics in nuclear condensates IA Klein, A Boija, LK Afeyan, SW Hawken, M Fan, A Dall'Agnese, O Oksuz, ... Science 368 (6497), 1386-1392, 2020 | 337 | 2020 |
Biomolecular condensates in the nucleus BR Sabari, A Dall’Agnese, RA Young Trends in biochemical sciences 45 (11), 961-977, 2020 | 312 | 2020 |
Mediator condensates localize signaling factors to key cell identity genes AV Zamudio, A Dall’Agnese, JE Henninger, JC Manteiga, LK Afeyan, ... Molecular cell 76 (5), 753-766. e6, 2019 | 209 | 2019 |
MeCP2 links heterochromatin condensates and neurodevelopmental disease CH Li, EL Coffey, A Dall’Agnese, NM Hannett, X Tang, JE Henninger, ... Nature 586 (7829), 440-444, 2020 | 143 | 2020 |
The aryl hydrocarbon receptor modulates acute and late mast cell responses R Sibilano, B Frossi, M Calvaruso, L Danelli, E Betto, A Dall’Agnese, ... The Journal of Immunology 189 (1), 120-127, 2012 | 86 | 2012 |
Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer P Cejas, Y Xie, A Font-Tello, K Lim, S Syamala, X Qiu, AK Tewari, N Shah, ... Nature communications 12 (1), 5775, 2021 | 79 | 2021 |
Transcription factor-directed re-wiring of chromatin architecture for somatic cell nuclear reprogramming toward trans-differentiation A Dall’Agnese, L Caputo, C Nicoletti, J di Iulio, A Schmitt, S Gatto, Y Diao, ... Molecular cell 76 (3), 453-472. e8, 2019 | 77 | 2019 |
Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS R Ciarapica, E Carcarino, L Adesso, M De Salvo, G Bracaglia, ... BMC cancer 14, 1-15, 2014 | 75 | 2014 |
The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx) R Ciarapica, M De Salvo, E Carcarino, G Bracaglia, L Adesso, ... Oncogene 33 (32), 4173-4184, 2014 | 75 | 2014 |
Dynamic enhancer DNA methylation as basis for transcriptional and cellular heterogeneity of ESCs Y Song, PR van den Berg, S Markoulaki, F Soldner, A Dall’Agnese, ... Molecular cell 75 (5), 905-920. e6, 2019 | 73 | 2019 |
Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila MC Guida, RT Birse, A Dall’Agnese, PC Toto, SB Diop, A Mai, PD Adams, ... Nature Communications 10 (1), 193, 2019 | 66 | 2019 |
Praja1 E3 ubiquitin ligase promotes skeletal myogenesis through degradation of EZH2 upon p38α activation S Consalvi, A Brancaccio, A Dall’Agnese, PL Puri, D Palacios Nature Communications 8 (1), 13956, 2017 | 53 | 2017 |
BRD3 and BRD4 BET bromodomain proteins differentially regulate skeletal myogenesis TC Roberts, U Etxaniz, A Dall’Agnese, SY Wu, CM Chiang, PE Brennan, ... Scientific reports 7 (1), 6153, 2017 | 52 | 2017 |
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration D Sala, TJ Cunningham, MJ Stec, U Etxaniz, C Nicoletti, A Dall’Agnese, ... Nature communications 10 (1), 1796, 2019 | 44 | 2019 |
Brahma is required for cell cycle arrest and late muscle gene expression during skeletal myogenesis S Albini, P Coutinho Toto, A Dall'Agnese, B Malecova, C Cenciarelli, ... EMBO reports 16 (8), 1037-1050, 2015 | 44 | 2015 |
Genetic variation associated with condensate dysregulation in disease SF Banani, LK Afeyan, SW Hawken, JE Henninger, A Dall’Agnese, ... Developmental cell 57 (14), 1776-1788. e8, 2022 | 42 | 2022 |
DNA damage signaling mediates the functional antagonism between replicative senescence and terminal muscle differentiation L Latella, A Dall'Agnese, FB Sesillo, C Nardoni, M Cosentino, A Lahm, ... Genes & development 31 (7), 648-659, 2017 | 26 | 2017 |