An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity W Guo, Y Chen, X Zhou, A Kar, P Ray, X Chen, EJ Rao, M Yang, H Ye, ... Nature structural & molecular biology 18 (7), 822-830, 2011 | 351 | 2011 |
Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutieres syndrome-related SAMHD1 K Zhao, J Du, X Han, JL Goodier, P Li, X Zhou, W Wei, SL Evans, L Li, ... Cell reports 4 (6), 1108-1115, 2013 | 232 | 2013 |
RNA Helicase p68 (DDX5) Regulates tau Exon 10 Splicing by Modulating a Stem-Loop Structure at the 5′ Splice Site A Kar, K Fushimi, X Zhou, P Ray, C Shi, X Chen, Z Liu, S Chen, JY Wu Molecular and cellular biology 31 (9), 1812-1821, 2011 | 139 | 2011 |
Expression of human FUS protein in Drosophila leads to progressive neurodegeneration Y Chen, M Yang, J Deng, X Chen, Y Ye, L Zhu, J Liu, H Ye, Y Shen, Y Li, ... Protein & cell 2 (6), 477-486, 2011 | 122 | 2011 |
The DDB1–DCAF1–Vpr–UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction Y Wu, X Zhou, CO Barnes, M DeLucia, AE Cohen, AM Gronenborn, J Ahn, ... Nature structural & molecular biology 23 (10), 933-940, 2016 | 113 | 2016 |
Crystal Structure of ArgP from Mycobacterium tuberculosis Confirms Two Distinct Conformations of Full-length LysR Transcriptional Regulators and Reveals Its … X Zhou, Z Lou, S Fu, A Yang, H Shen, Z Li, Y Feng, M Bartlam, H Wang, ... Journal of molecular biology 396 (4), 1012-1024, 2010 | 84 | 2010 |
A novel DCAF 1‐binding motif required for Vpx‐mediated degradation of nuclear SAMHD 1 and Vpr‐induced G 2 arrest W Wei, H Guo, X Han, X Liu, X Zhou, W Zhang, XF Yu Cellular microbiology 14 (11), 1745-1756, 2012 | 72 | 2012 |
The proline-rich domain and the microtubule binding domain of protein tau acting as RNA binding domains XS Wang, DL Wang, J Zhao, MH Qu, XH Zhou, HJ He, RQ He Protein and peptide letters 13 (7), 679-685, 2006 | 69 | 2006 |
Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components X Zhou, SL Evans, X Han, Y Liu, XF Yu PLoS One 7 (3), e33495, 2012 | 59 | 2012 |
Reduced APOBEC3H variant anti-viral activities are associated with altered RNA binding activities A Zhen, J Du, X Zhou, Y Xiong, XF Yu Public Library of Science 7 (7), e38771, 2012 | 56 | 2012 |
SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr)*♦ X Zhou, M DeLucia, J Ahn Journal of Biological Chemistry 291 (33), 16936-16947, 2016 | 45 | 2016 |
The Crystal Structure of MCAT from Mycobacterium tuberculosis Reveals Three New Catalytic Models Z Li, Y Huang, J Ge, H Fan, X Zhou, S Li, M Bartlam, H Wang, Z Rao Journal of molecular biology 371 (4), 1075-1083, 2007 | 43 | 2007 |
N-terminal horseshoe conformation of DCC is functionally required for axon guidance and might be shared by other neural receptors Q Chen, X Sun, X Zhou, J Liu, J Wu, Y Zhang, J Wang Journal of cell science 126 (1), 186-195, 2013 | 39 | 2013 |
Substrate specificity of SAMHD1 triphosphohydrolase activity is controlled by deoxyribonucleoside triphosphates and phosphorylation at Thr592 S Jang, X Zhou, J Ahn Biochemistry 55 (39), 5635-5646, 2016 | 34 | 2016 |
Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 … X Han, W Liang, D Hua, X Zhou, J Du, SL Evans, Q Gao, H Wang, ... Journal of virology 88 (6), 3320-3328, 2014 | 34 | 2014 |
Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta J Du, K Zhao, Y Rui, P Li, X Zhou, W Zhang, XF Yu Journal of virology 87 (3), 1906-1911, 2013 | 33 | 2013 |
HIV-1 Vpr protein directly loads helicase-like transcription factor (HLTF) onto the CRL4-DCAF1 E3 ubiquitin ligase X Zhou, M DeLucia, C Hao, K Hrecka, C Monnie, J Skowronski, J Ahn Journal of Biological Chemistry 292 (51), 21117-21127, 2017 | 28 | 2017 |
HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3 SL Evans, A Schön, Q Gao, X Han, X Zhou, E Freire, XF Yu Retrovirology 11, 1-11, 2014 | 27 | 2014 |
Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression X Zhou, X Han, K Zhao, J Du, SL Evans, H Wang, P Li, W Zheng, Y Rui, ... Journal of virology 88 (5), 2555-2563, 2014 | 23 | 2014 |
Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family H Dong, X Li, Z Lou, X Xu, D Su, X Zhou, W Zhou, M Bartlam, Z Rao Journal of Molecular Biology 383 (3), 455-464, 2008 | 21 | 2008 |