The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF 8 AN Singh, J Oehler, I Torrecilla, S Kilgas, S Li, B Vaz, C Guérillon, ... The EMBO journal 38 (21), e102361, 2019 | 54 | 2019 |
The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability A Ruggiano, B Vaz, S Kilgas, M Popović, G Rodriguez-Berriguete, ... Cell Reports 37 (10), 2021 | 36 | 2021 |
The role of extracellular adenosine triphosphate in ischemic organ injury H Zhao, S Kilgas, A Alam, S Eguchi, D Ma Critical care medicine 44 (5), 1000-1012, 2016 | 36 | 2016 |
p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation S Kilgas, AN Singh, S Paillas, CK Then, I Torrecilla, J Nicholson, ... Cell reports 35 (8), 2021 | 30 | 2021 |
Inhibitors of the ATPase p97/VCP: From basic research to clinical applications S Kilgas, K Ramadan Cell Chemical Biology 30 (1), 3-21, 2023 | 26 | 2023 |
The histone deacetylase inhibitor romidepsin spares normal tissues while acting as an effective radiosensitizer in bladder tumors in vivo S Paillas, CK Then, S Kilgas, JL Ruan, J Thompson, A Elliott, S Smart, ... International Journal of Radiation Oncology* Biology* Physics 107 (1), 212-221, 2020 | 25 | 2020 |
Immunofluorescence microscopy-based detection of ssDNA foci by BrdU in mammalian cells S Kilgas, AE Kiltie, K Ramadan STAR protocols 2 (4), 100978, 2021 | 14 | 2021 |
SPRTN protease and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability B Vaz, A Ruggiano, M Popovic, G Rodriguez-Berriguete, S Kilgas, ... bioRxiv, 2020.02. 14.949289, 2020 | 5 | 2020 |
NEAT1 modulates the TIRR/53BP1 complex to maintain genome integrity S Kilgas, A Syed, P Toolan-Kerr, ML Swift, S Roychoudhury, A Sarkar, ... Nature Communications 15 (1), 8438, 2024 | | 2024 |
53BP1 loss elicits cGAS-STING-dependent antitumor immunity in ovarian and pancreatic cancer Y Sun, J Patterson-Fortin, S Han, Z Li, Z Nowicka, Y Hirohashi, S Kilgas, ... Nature Communications 15 (1), 6676, 2024 | | 2024 |
Abstract A015: 53BP1 loss mediated PARP inhibitor resistance in BRCA1-deficient pancreatic cancer is overcome with immune checkpoint blockade J Patterson-Fortin, Y Sun, S Han, Z Li, Z Nowicka, Y Hirohashi, S Kilgas, ... Cancer Research 84 (1_Supplement), A015-A015, 2024 | | 2024 |
53BP1 loss mediated PARP inhibitor resistance in BRCA1-deficient pancreatic cancer is overcome with immune checkpoint blockade J Patterson-Fortin, Y Sun, S Han, Z Li, Z Nowicka, Y Hirohashi, S Kilgas, ... CANCER RESEARCH 84 (1), 2024 | | 2024 |
p97/VCP regulates MRE11-dependent DNA and resection and alters cellular toxicity of ionising radiation S Kilgas University of Oxford, 2021 | | 2021 |
The role of p97/VCP co-factor UBXD8/FAF2 in DNA damage response S Kilgas University of Oxford, 2017 | | 2017 |