| Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance TR Koves, JR Ussher, RC Noland, D Slentz, M Mosedale, O Ilkayeva, ... Cell metabolism 7 (1), 45-56, 2008 | 2148 | 2008 |
| The failing heart relies on ketone bodies as a fuel G Aubert, OJ Martin, JL Horton, L Lai, RB Vega, TC Leone, T Koves, ... Circulation 133 (8), 698-705, 2016 | 642 | 2016 |
| Peroxisome proliferator-activated receptor-γ co-activator 1α-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced … TR Koves, P Li, J An, T Akimoto, D Slentz, O Ilkayeva, GL Dohm, Z Yan, ... Journal of Biological Chemistry 280 (39), 33588-33598, 2005 | 571 | 2005 |
| Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance J An, DM Muoio, M Shiota, Y Fujimoto, GW Cline, GI Shulman, TR Koves, ... Nature medicine 10 (3), 268-274, 2004 | 540 | 2004 |
| Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control RC Noland, TR Koves, SE Seiler, H Lum, RM Lust, O Ilkayeva, ... Journal of biological chemistry 284 (34), 22840-22852, 2009 | 406 | 2009 |
| Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption JR Ussher, TR Koves, VJJ Cadete, L Zhang, JS Jaswal, SJ Swyrd, ... Diabetes 59 (10), 2453-2464, 2010 | 405 | 2010 |
| Muscle-specific deletion of carnitine acetyltransferase compromises glucose tolerance and metabolic flexibility DM Muoio, RC Noland, JP Kovalik, SE Seiler, MN Davies, KL DeBalsi, ... Cell metabolism 15 (5), 764-777, 2012 | 398 | 2012 |
| SIRT4 coordinates the balance between lipid synthesis and catabolism by repressing malonyl CoA decarboxylase G Laurent, NJ German, AK Saha, VCJ de Boer, M Davies, TR Koves, ... Molecular cell 50 (5), 686-698, 2013 | 394 | 2013 |
| Differences in extracellular dopamine concentrations in the nucleus accumbens during response-dependent and response-independent cocaine administration in the rat SE Hemby, C Co, TR Koves, JE Smith, SI Dworkin Psychopharmacology 133, 7-16, 1997 | 350 | 1997 |
| Adipose acyl-CoA synthetase-1 directs fatty acids toward β-oxidation and is required for cold thermogenesis JM Ellis, LO Li, PC Wu, TR Koves, O Ilkayeva, RD Stevens, SM Watkins, ... Cell metabolism 12 (1), 53-64, 2010 | 349 | 2010 |
| Energy metabolic reprogramming in the hypertrophied and early stage failing heart: a multisystems approach L Lai, TC Leone, MP Keller, OJ Martin, AT Broman, J Nigro, K Kapoor, ... Circulation: Heart Failure 7 (6), 1022-1031, 2014 | 272 | 2014 |
| Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and β-oxidation and alters phospholipid fatty acid composition LO Li, JM Ellis, HA Paich, S Wang, N Gong, G Altshuller, RJ Thresher, ... Journal of Biological Chemistry 284 (41), 27816-27826, 2009 | 247 | 2009 |
| Subsarcolemmal and intermyofibrillar mitochondria play distinct roles in regulating skeletal muscle fatty acid metabolism TR Koves, RC Noland, AL Bates, ST Henes, DM Muoio, RN Cortright American Journal of Physiology-Cell Physiology 288 (5), C1074-C1082, 2005 | 206 | 2005 |
| Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs fatty acid oxidation and induces cardiac hypertrophy JM Ellis, SM Mentock, MA DePetrillo, TR Koves, S Sen, SM Watkins, ... Molecular and cellular biology 31 (6), 1252-1262, 2011 | 205 | 2011 |
| Skeletal muscle adaptation to fatty acid depends on coordinated actions of the PPARs and PGC1α: implications for metabolic disease DM Muoio, TR Koves Applied Physiology, Nutrition, and Metabolism 32 (5), 874-883, 2007 | 177 | 2007 |
| Electrical stimulation increases hypertrophy and metabolic flux in tissue-engineered human skeletal muscle A Khodabukus, L Madden, NK Prabhu, TR Koves, CP Jackman, ... Biomaterials 198, 259-269, 2019 | 168 | 2019 |
| Measurement of fatty acid oxidation rates in animal tissues and cell lines FK Huynh, MF Green, TR Koves, MD Hirschey Methods in enzymology 542, 391-405, 2014 | 165 | 2014 |
| Insulin-stimulated cardiac glucose oxidation is increased in high-fat diet–induced obese mice lacking malonyl CoA decarboxylase JR Ussher, TR Koves, JS Jaswal, L Zhang, O Ilkayeva, JRB Dyck, ... Diabetes 58 (8), 1766-1775, 2009 | 147 | 2009 |
| Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness KM Huffman, TR Koves, MJ Hubal, H Abouassi, N Beri, LA Bateman, ... Diabetologia 57, 2282-2295, 2014 | 146 | 2014 |
| A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults CL Kien, JY Bunn, ME Poynter, R Stevens, J Bain, O Ikayeva, ... Diabetes 62 (4), 1054-1063, 2013 | 142 | 2013 |
