Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data CM Rudin, JT Poirier, LA Byers, C Dive, A Dowlati, J George, JV Heymach, ... Nature Reviews Cancer 19 (5), 289-297, 2019 | 912 | 2019 |
MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to aurora kinase inhibition G Mollaoglu, MR Guthrie, S Böhm, J Brägelmann, I Can, PM Ballieu, ... Cancer cell 31 (2), 270-285, 2017 | 499 | 2017 |
Transcriptional profiling of the Sonic hedgehog response: a critical role for N-myc in proliferation of neuronal precursors TG Oliver, LL Grasfeder, AL Carroll, C Kaiser, CL Gillingham, SM Lin, ... Proceedings of the National Academy of Sciences 100 (12), 7331-7336, 2003 | 439 | 2003 |
MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer cell 38 (1), 60-78. e12, 2020 | 333 | 2020 |
Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma TG Oliver, TA Read, JD Kessler, A Mehmeti, JF Wells, TTT Huynh, SM Lin, ... Oxford University Press for The Company of Biologists Limited 132 (10), 2425 …, 2005 | 311 | 2005 |
Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer CA Stewart, CM Gay, Y Xi, S Sivajothi, V Sivakamasundari, J Fujimoto, ... Nature cancer 1 (4), 423-436, 2020 | 294 | 2020 |
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer TG Oliver, KL Mercer, LC Sayles, JR Burke, D Mendus, KS Lovejoy, ... Genes & development 24 (8), 837-852, 2010 | 247 | 2010 |
Suppression of Rev3, the catalytic subunit of Polζ, sensitizes drug-resistant lung tumors to chemotherapy J Doles, TG Oliver, ER Cameron, G Hsu, T Jacks, GC Walker, MT Hemann Proceedings of the National Academy of Sciences 107 (48), 20786-20791, 2010 | 220 | 2010 |
Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes W Zhang, L Girard, YA Zhang, T Haruki, M Papari-Zareei, V Stastny, ... Translational lung cancer research 7 (1), 32, 2018 | 218 | 2018 |
Caspase-2-mediated cleavage of Mdm2 creates a p53-induced positive feedback loop TG Oliver, E Meylan, GP Chang, W Xue, JR Burke, TJ Humpton, ... Molecular cell 43 (1), 57-71, 2011 | 176 | 2011 |
Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells MP Fogarty, BA Emmenegger, LL Grasfeder, TG Oliver, ... Proceedings of the National Academy of Sciences 104 (8), 2973-2978, 2007 | 172 | 2007 |
Inosine monophosphate dehydrogenase dependence in a subset of small cell lung cancers F Huang, M Ni, MD Chalishazar, KE Huffman, J Kim, L Cai, X Shi, F Cai, ... Cell metabolism 28 (3), 369-382. e5, 2018 | 170 | 2018 |
The lineage-defining transcription factors SOX2 and NKX2-1 determine lung cancer cell fate and shape the tumor immune microenvironment G Mollaoglu, A Jones, SJ Wait, A Mukhopadhyay, S Jeong, R Arya, ... Immunity 49 (4), 764-779. e9, 2018 | 169 | 2018 |
New approaches to SCLC therapy: from the laboratory to the clinic JT Poirier, J George, TK Owonikoko, A Berns, E Brambilla, LA Byers, ... Journal of Thoracic Oncology 15 (4), 520-540, 2020 | 158 | 2020 |
MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion MD Chalishazar, SJ Wait, F Huang, AS Ireland, A Mukhopadhyay, Y Lee, ... Clinical Cancer Research 25 (16), 5107-5121, 2019 | 152 | 2019 |
Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma W Xue, E Meylan, TG Oliver, DM Feldser, MM Winslow, R Bronson, ... Cancer discovery 1 (3), 236-247, 2011 | 152 | 2011 |
GLUT3 is induced during epithelial-mesenchymal transition and promotes tumor cell proliferation in non-small cell lung cancer M Masin, J Vazquez, S Rossi, S Groeneveld, N Samson, PC Schwalie, ... Cancer & metabolism 2, 1-14, 2014 | 147 | 2014 |
Getting at the root and stem of brain tumors TG Oliver, RJ Wechsler-Reya Neuron 42 (6), 885-888, 2004 | 143 | 2004 |
Aurora-A kinase is essential for bipolar spindle formation and early development DO Cowley, JA Rivera-Pérez, M Schliekelman, YJ He, TG Oliver, L Lu, ... Molecular and cellular biology 29 (4), 1059-1071, 2009 | 139 | 2009 |
Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer AH Wagner, S Devarakonda, ZL Skidmore, K Krysiak, A Ramu, L Trani, ... Nature communications 9 (1), 3787, 2018 | 137 | 2018 |