Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection W Abdullahi, D Tripathi, PT Ronaldson American Journal of Physiology-Cell Physiology 315 (3), C343-C356, 2018 | 453 | 2018 |
Transporters at CNS barrier sites: obstacles or opportunities for drug delivery? L Sanchez-Covarrubias, LM Slosky, BJ Thompson, TP Davis, ... Current pharmaceutical design 20 (10), 1422-1449, 2014 | 268 | 2014 |
In situ localization of P-glycoprotein (ABCB1) in human and rat brain R Bendayan, PT Ronaldson, D Gingras, M Bendayan Journal of Histochemistry & Cytochemistry 54 (10), 1159-1167, 2006 | 267 | 2006 |
Structure, function, and regulation of the blood-brain barrier tight junction in central nervous system disorders JJ Lochhead, J Yang, PT Ronaldson, TP Davis Frontiers in physiology 11, 558491, 2020 | 259 | 2020 |
Regulation of blood–brain barrier integrity by microglia in health and disease: a therapeutic opportunity PT Ronaldson, TP Davis Journal of Cerebral Blood Flow & Metabolism 40 (1_suppl), S6-S24, 2020 | 245 | 2020 |
Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke P T Ronaldson, T P Davis Current pharmaceutical design 18 (25), 3624-3644, 2012 | 185 | 2012 |
HIV-1 viral envelope glycoprotein gp120 triggers an inflammatory response in cultured rat astrocytes and regulates the functional expression of P-glycoprotein PT Ronaldson, R Bendayan Molecular pharmacology 70 (3), 1087-1098, 2006 | 165 | 2006 |
Transforming growth factor-β signaling alters substrate permeability and tight junction protein expression at the blood-brain barrier during inflammatory pain PT Ronaldson, KM DeMarco, L Sanchez-Covarrubias, CM Solinsky, ... Journal of Cerebral Blood Flow & Metabolism 29 (6), 1084-1098, 2009 | 162 | 2009 |
Up‐regulation of P‐glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line JA Zastre, GNY Chan, PT Ronaldson, M Ramaswamy, PO Couraud, ... Journal of neuroscience research 87 (4), 1023-1036, 2009 | 144 | 2009 |
HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells PT Ronaldson, R Bendayan Journal of neurochemistry 106 (3), 1298-1313, 2008 | 123 | 2008 |
Regulation of ABC membrane transporters in glial cells: Relevance to the pharmacotherapy of brain HIV‐1 infection PT Ronaldson, Y Persidsky, R Bendayan Glia 56 (16), 1711-1735, 2008 | 119 | 2008 |
Drug delivery to the ischemic brain BJ Thompson, PT Ronaldson Advances in pharmacology 71, 165-202, 2014 | 117 | 2014 |
Cellular localization and functional expression of P‐glycoprotein in rat astrocyte cultures PT Ronaldson, M Bendayan, D Gingras, M Piquette‐Miller, R Bendayan Journal of neurochemistry 89 (3), 788-800, 2004 | 115 | 2004 |
Multidrug resistance protein (MRP) 4-and MRP 5-mediated efflux of 9-(2-phosphonylmethoxyethyl) adenine by microglia S Dallas, L Schlichter, R Bendayan Journal of Pharmacology and Experimental Therapeutics 309 (3), 1221-1229, 2004 | 114 | 2004 |
Distribution of insulin in trigeminal nerve and brain after intranasal administration JJ Lochhead, KL Kellohen, PT Ronaldson, TP Davis Scientific reports 9 (1), 2621, 2019 | 106 | 2019 |
Regulation of multidrug resistance protein 1 by tumor necrosis factor α in cultured glial cells: involvement of nuclear factor-κB and c-Jun N-terminal kinase signaling pathways PT Ronaldson, T Ashraf, R Bendayan Molecular pharmacology 77 (4), 644-659, 2010 | 94 | 2010 |
Targeted drug delivery to treat pain and cerebral hypoxia PT Ronaldson, TP Davis Pharmacological reviews 65 (1), 291-314, 2013 | 87 | 2013 |
Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier PT Ronaldson, JD Finch, KM DeMarco, CE Quigley, TP Davis Journal of Pharmacology and Experimental Therapeutics 336 (3), 827-839, 2011 | 87 | 2011 |
Hypoxia/reoxygenation stress signals an increase in organic anion transporting polypeptide 1a4 (Oatp1a4) at the blood–brain barrier: relevance to CNS drug delivery BJ Thompson, L Sanchez-Covarrubias, LM Slosky, Y Zhang, ... Journal of Cerebral Blood Flow & Metabolism 34 (4), 699-707, 2014 | 84 | 2014 |
P‐glycoprotein trafficking at the blood–brain barrier altered by peripheral inflammatory hyperalgesia G McCaffrey, WD Staatz, L Sanchez‐Covarrubias, JD Finch, K DeMarco, ... Journal of neurochemistry 122 (5), 962-975, 2012 | 79 | 2012 |