Microhomologies are prevalent at Cas9-induced larger deletions DDG Owens, A Caulder, V Frontera, JR Harman, AJ Allan, A Bucakci, ... Nucleic acids research 47 (14), 7402-7417, 2019 | 124 | 2019 |
A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization D Dilworth, RP Hanley, R Ferreira de Freitas, A Allali-Hassani, M Zhou, ... Nature chemical biology 18 (1), 56-63, 2022 | 58 | 2022 |
Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development DDG Owens, G Anselmi, AM Oudelaar, DJ Downes, A Cavallo, ... Nature Communications 13 (1), 773, 2022 | 18 | 2022 |
Recruitment of FBXO22 for targeted degradation of NSD2 DY Nie, JR Tabor, J Li, M Kutera, J St-Germain, RP Hanley, E Wolf, ... Nature Chemical Biology, 1-11, 2024 | 9 | 2024 |
A chemical probe to modulate human GID4 Pro/N-degron interactions DDG Owens, MER Maitland, A Khalili Yazdi, X Song, V Reber, ... Nature Chemical Biology, 1-12, 2024 | 6 | 2024 |
Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6 RJ Harding, I Franzoni, MK Mann, MM Szewczyk, B Mirabi, ... Journal of Medicinal Chemistry 66 (15), 10273-10288, 2023 | 5 | 2023 |
Recreating Tissue Structures Representative of Teratomas In Vitro Using a Combination of 3D Cell Culture Technology and Human Embryonic Stem Cells A Hidalgo Aguilar, L Smith, D Owens, R Quelch, S Przyborski Bioengineering 9 (5), 185, 2022 | 5 | 2022 |
Measuring Protein–Protein Interactions in Cells using Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET) Assay MM Szewczyk, DDG Owens, D Barsyte-Lovejoy Chemogenomics: Methods and Protocols, 137-148, 2023 | 4 | 2023 |
Using advanced cell culture techniques to differentiate pluripotent stem cells and recreate tissue structures representative of teratoma xenografts LA Smith, A Hidalgo Aguilar, DDG Owens, RH Quelch, E Knight, ... Frontiers in Cell and Developmental Biology 9, 667246, 2021 | 4 | 2021 |
Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex MER Maitland, G Onea, DDG Owens, BC Gonga-Cavé, X Wang, ... bioRxiv, 2024.03. 08.584134, 2024 | 1 | 2024 |
Modelling the Development of Tissues In Vitro from Pluripotent Stem Cells D OWENS, G DAVID Durham University, 2016 | 1 | 2016 |
Therapeutic Discovery for Chromatin Complexes: Where Do We Stand? DDG Owens, MER Maitland, CH Arrowsmith, D Barsyte-Lovejoy Annual Review of Cancer Biology 8, 2024 | | 2024 |
Measuring Protein-Protein Interactions in Cells using Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET) Assay TN Assay, MM Szewczyk, DDG Owens, D Barsyte-Lovejoy Chemogenomics: Methods and Protocols 2706, 137, 2023 | | 2023 |
2018–RECONSTRUCTION OF A DORSAL AORTA HEMOGENIC ENDOTHELIUM GENE REGULATORY NETWORK IDENTIFIES A RUNX1: IKZF1: NOTCH FEED-FORWARD LOOP J Harman, L Greder, G Swiers, D Owens, M Suciu, D Downes, J Telenius, ... Experimental Hematology 100, S36, 2021 | | 2021 |
Modelling the Development of Human Tissues In Vitro Using Mammalian Stem Cells and Advanced Cell Technologies L Smith, D Owens, S Przyborski JOURNAL OF ANATOMY 236, 277-277, 2020 | | 2020 |
Modelling the development of human tissues in vitro using advanced cell technologies and mammalian stem cells LA Smith, D Owens, SA Przyborski JOURNAL OF ANATOMY 236 (1), 194-195, 2020 | | 2020 |
Elucidating the cis-regulatory logic of Runx1 during developmental haematopoiesis DDG Owens University of Oxford, 2019 | | 2019 |
Dynamic Regulation of Runx1 at the Onset of Definitive Hematopoiesis D Owens, C Rode, V Frontera, L Greder, A Jarratt, J Harman, D Downes, ... Experimental Hematology 64, S91, 2018 | | 2018 |