In vivo demonstration that α-synuclein oligomers are toxic B Winner, R Jappelli, SK Maji, PA Desplats, L Boyer, S Aigner, C Hetzer, ... Proceedings of the National Academy of Sciences 108 (10), 4194-4199, 2011 | 1727 | 2011 |
Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector F Felici, L Castagnoli, A Musacchio, R Jappelli, G Cesareni Journal of molecular biology 222 (2), 301-310, 1991 | 837 | 1991 |
Modeling hippocampal neurogenesis using human pluripotent stem cells DX Yu, FP Di Giorgio, J Yao, MC Marchetto, K Brennand, R Wright, A Mei, ... Stem cell reports 2 (3), 295-310, 2014 | 317 | 2014 |
Evidence that a salt bridge in the light chain contributes to the physical stability difference between heavy and light human ferritins. P Santambrogio, S Levi, P Arosio, L Palagi, G Vecchio, DM Lawson, ... Journal of Biological Chemistry 267 (20), 14077-14083, 1992 | 167 | 1992 |
Predicting the functional states of human iPSC-derived neurons with single-cell RNA-seq and electrophysiology C Bardy, M Van Den Hurk, B Kakaradov, JA Erwin, BN Jaeger, ... Molecular psychiatry 21 (11), 1573-1588, 2016 | 158 | 2016 |
Generation of functional human serotonergic neurons from fibroblasts KC Vadodaria, J Mertens, A Paquola, C Bardy, X Li, R Jappelli, L Fung, ... Molecular psychiatry 21 (1), 49-61, 2016 | 141 | 2016 |
Efficient generation of CA3 neurons from human pluripotent stem cells enables modeling of hippocampal connectivity in vitro A Sarkar, A Mei, ACM Paquola, S Stern, C Bardy, JR Klug, S Kim, ... Cell stem cell 22 (5), 684-697. e9, 2018 | 132 | 2018 |
Short promoters in viral vectors drive selective expression in mammalian inhibitory neurons, but do not restrict activity to specific inhibitory cell-types JL Nathanson, R Jappelli, ED Scheeff, G Manning, K Obata, S Brenner, ... Frontiers in neural circuits 3, 775, 2009 | 124 | 2009 |
In vitro myelin formation using embryonic stem cells BE Kerman, HJ Kim, K Padmanabhan, A Mei, S Georges, MS Joens, ... Development 142 (12), 2213-2225, 2015 | 105 | 2015 |
Identification of a putative binding site for negatively charged surfaces in the fibronectin type II domain of human factor XII F Citarella, H te Velthuis, M Helmer-Citterich, CE Hack Thrombosis and haemostasis 84 (12), 1057-1065, 2000 | 60 | 2000 |
Loop mutations can cause a substantial conformational change in the carboxy terminus of the ferritin protein R Jappelli, A Luzzago, P Tataseo, I Pernice, G Cesareni Journal of molecular biology 227 (2), 532-543, 1992 | 45 | 1992 |
Protein design on computers. Five new proteins: Shpilka, grendel, fingerclasp, leather, and aida C Sander, G Vriend, F Bazan, A Horovitz, H Nakamura, L Ribas, ... Proteins: Structure, Function, and Bioinformatics 12 (2), 105-110, 1992 | 34 | 1992 |
Retinoic acid regulation of the Mesp–Ripply feedback loop during vertebrate segmental patterning TA Moreno, R Jappelli, JCI Belmonte, C Kintner Developmental biology 315 (2), 317-330, 2008 | 33 | 2008 |
Analysis of mRNAs under translational control during Xenopus embryogenesis: isolation of new ribosomal protein clones F Loreni, A Francesconi, R Jappelli, F Amaldi Nucleic acids research 20 (8), 1859-1863, 1992 | 22 | 1992 |
Expression and functional characterization of membrane-integrated mammalian corticotropin releasing factor receptors 1 and 2 in Escherichia coli R Jappelli, MH Perrin, KA Lewis, JM Vaughan, C Tzitzilonis, JE Rivier, ... PloS one 9 (1), e84013, 2014 | 20 | 2014 |
Interaction between cAMP-dependent protein kinase catalytic subunit and peptide inhibitors analyzed with λ repressor fusions R Jappelli, S Brenner Journal of molecular biology 259 (4), 575-578, 1996 | 15 | 1996 |
A genetic screen to identify sequences that mediate protein oligomerization in Escherichia coli R Jappelli, S Brenner Biochemical and Biophysical Research Communications 266 (1), 243-247, 1999 | 9 | 1999 |
Cooperativity of mutational effects within a six amino acid residues substitution that induces a major conformational change in human H ferritin R Jappelli, G Cesareni Biochemical and biophysical research communications 250 (2), 342-346, 1998 | 9 | 1998 |
Changes in the periplasmic linker and in the expression level affect the activity of ToxR and λ-ToxR fusion proteins in Escherichia coli R Jappelli, S Brenner FEBS letters 423 (3), 371-375, 1998 | 9 | 1998 |
Loop mutations affect ferritin solubility causing non‐native aggregation of subunits or precipitation of fully assembled polymers R Jappelli, G Cesareni FEBS letters 394 (3), 311-315, 1996 | 8 | 1996 |