Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition A Goldman, B Majumder, A Dhawan, S Ravi, D Goldman, M Kohandel, ... Nature communications 6 (1), 6139, 2015 | 248 | 2015 |
NSC348884, a nucleophosmin inhibitor disrupts oligomer formation and induces apoptosis in human cancer cells W Qi, K Shakalya, A Stejskal, A Goldman, S Beeck, L Cooke, ... Oncogene 27 (30), 4210-4220, 2008 | 140 | 2008 |
Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype M Boareto, MK Jolly, A Goldman, M Pietilä, SA Mani, S Sengupta, ... Journal of the Royal Society Interface 13 (118), 20151106, 2016 | 127 | 2016 |
Advances in understanding the role of P-gp in doxorubicin resistance: Molecular pathways, therapeutic strategies, and prospects S Mirzaei, MH Gholami, F Hashemi, A Zabolian, MV Farahani, ... Drug Discovery Today 27 (2), 436-455, 2022 | 118 | 2022 |
A novel mechanism of acid and bile acid-induced DNA damage involving Na+/H+ exchanger: implication for Barrett's oesophagus A Goldman, M Shahidullah, D Goldman, L Khailova, G Watts, N Delamere, ... Gut 59 (12), 1606-1616, 2010 | 80 | 2010 |
Reporter nanoparticle that monitors its anticancer efficacy in real time A Kulkarni, P Rao, S Natarajan, A Goldman, VS Sabbisetti, Y Khater, ... Proceedings of the National Academy of Sciences 113 (15), E2104-E2113, 2016 | 77 | 2016 |
Rationally designed 2-in-1 nanoparticles can overcome adaptive resistance in cancer A Goldman, A Kulkarni, M Kohandel, P Pandey, P Rao, SK Natarajan, ... ACS nano 10 (6), 5823-5834, 2016 | 69 | 2016 |
Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance A Goldman, S Khiste, E Freinkman, A Dhawan, B Majumder, J Mondal, ... Science signaling 12 (595), eaas8779, 2019 | 59 | 2019 |
Preclinical cancer models and biomarkers for drug development: new technologies and emerging tools M Dhandapani, A Goldman Journal of molecular biomarkers & diagnosis 8 (5), 2017 | 58 | 2017 |
Engineering in medicine to address the challenge of cancer drug resistance: from micro-and nanotechnologies to computational and mathematical modeling M Craig, AL Jenner, B Namgung, LP Lee, A Goldman Chemical Reviews 121 (6), 3352-3389, 2020 | 54 | 2020 |
Dynamic microenvironment induces phenotypic plasticity of esophageal cancer cells under flow G Calibasi Kocal, S Güven, K Foygel, A Goldman, P Chen, S Sengupta, ... Scientific reports 6 (1), 38221, 2016 | 54 | 2016 |
Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects HR Molavian, A Goldman, CJ Phipps, M Kohandel, BG Wouters, ... Scientific Reports 6 (1), 27439, 2016 | 47 | 2016 |
Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells A Goldman, A Condon, E Adler, M Minnella, C Bernstein, H Bernstein, ... Diseases of the Esophagus 23 (2), 83-93, 2010 | 47 | 2010 |
Cancer immunotherapy and personalized medicine: emerging technologies and biomarker-based approaches L Maciejko, M Smalley, A Goldman Journal of molecular biomarkers & diagnosis 8 (5), 2017 | 46 | 2017 |
Characterization of squamous esophageal cells resistant to bile acids at acidic pH: implication for Barrett's esophagus pathogenesis A Goldman, HDR Chen, HB Roesly, KA Hill, ME Tome, B Dvorak, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (2 …, 2011 | 46 | 2011 |
Sequential application of a cytotoxic nanoparticle and a PI3K inhibitor enhances antitumor efficacy A Pandey, A Kulkarni, B Roy, A Goldman, S Sarangi, P Sengupta, ... Cancer research 74 (3), 675-685, 2014 | 38 | 2014 |
Barrett's esophagus: prevalence–incidence and etiology–origins GW Falk, BC Jacobson, RH Riddell, JH Rubenstein, H El‐Zimaity, ... Annals of the New York Academy of Sciences 1232 (1), 1-17, 2011 | 37 | 2011 |
Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment N Kumar, P Prasad, E Jash, M Saini, A Husain, A Goldman, S Sehrawat Molecular and cellular biochemistry 447 (1), 77-92, 2018 | 36 | 2018 |
The Na+/H+ exchanger controls deoxycholic acid-induced apoptosis by a H+-activated, Na+-dependent ionic shift in esophageal cells A Goldman, HDR Chen, MR Khan, H Roesly, KA Hill, M Shahidullah, ... PLoS One 6 (8), e23835, 2011 | 28 | 2011 |
Cooperative adaptation to therapy (CAT) confers resistance in heterogeneous non-small cell lung cancer M Craig, K Kaveh, A Woosley, AS Brown, D Goldman, E Eton, RM Mehta, ... PLoS computational biology 15 (8), e1007278, 2019 | 27 | 2019 |