Resolving heterogeneous macromolecular assemblies by Orbitrap-based single-particle charge detection mass spectrometry TP Wörner, J Snijder, A Bennett, M Agbandje-McKenna, AA Makarov, ... Nature methods 17 (4), 395-398, 2020 | 153 | 2020 |
Adeno-associated virus capsid assembly is divergent and stochastic TP Wörner, A Bennett, S Habka, J Snijder, O Friese, T Powers, ... Nature communications 12 (1), 1642, 2021 | 119 | 2021 |
Bacterial encapsulins as orthogonal compartments for mammalian cell engineering F Sigmund, C Massner, P Erdmann, A Stelzl, H Rolbieski, M Desai, ... Nature communications 9 (1), 1990, 2018 | 103 | 2018 |
Mass spectrometry-based structural virology TP Wörner, TM Shamorkina, J Snijder, AJR Heck Analytical Chemistry 93 (1), 620-640, 2020 | 48 | 2020 |
Complete and cooperative in vitro assembly of computationally designed self-assembling protein nanomaterials AJ Wargacki, TP Wörner, M van de Waterbeemd, D Ellis, AJR Heck, ... Nature communications 12 (1), 883, 2021 | 45 | 2021 |
Assessment of genome packaging in AAVs using Orbitrap-based charge-detection mass spectrometry TP Wörner, J Snijder, O Friese, T Powers, AJR Heck Molecular Therapy-Methods & Clinical Development 24, 40-47, 2022 | 35 | 2022 |
Mild acid elution and MHC immunoaffinity chromatography reveal similar albeit not identical profiles of the HLA class I immunopeptidome T Sturm, B Sautter, TP Wörner, S Stevanović, HG Rammensee, O Planz, ... Journal of proteome research 20 (1), 289-304, 2020 | 34 | 2020 |
Frequency chasing of individual megadalton ions in an Orbitrap analyser improves precision of analysis in single-molecule mass spectrometry TP Wörner, K Aizikov, J Snijder, KL Fort, AA Makarov, AJR Heck Nature chemistry 14 (5), 515-522, 2022 | 31 | 2022 |
Adeno-associated virus capsid assembly is divergent and stochastic. Nat. Commun. 12, 1642 TP Wörner, A Bennett, S Habka, J Snijder, O Friese, T Powers, ... | 15 | 2021 |
Site‐specific functionality and tryptophan mimicry of lipidation in tetraspanin CD9 V Neviani, S van Deventer, TP Wörner, KT Xenaki, M van de Waterbeemd, ... The FEBS journal 287 (24), 5323-5344, 2020 | 14 | 2020 |
Ultralong transients enhance sensitivity and resolution in Orbitrap-based single-ion mass spectrometry E Deslignière, VC Yin, EHTM Ebberink, AD Rolland, A Barendregt, ... Nature Methods, 1-4, 2024 | 5 | 2024 |
Resolving heterogeneous high-mass macromolecular machineries by Orbitrap-based single particle charge detection mass spectrometry TP Wörner, J Snijder, A Bennett, M Agbandje-McKenna, AA Makarov, ... BioRxiv, 717413, 2019 | 1 | 2019 |
Site-specific functionality of lipidation in tetraspanin CD9 revealed by tryptophan mimicry V Neviani, S van Deventer, TP Wörner, KT Xenaki, M van de Waterbeemd, ... Unravelling the molecular mechanisms of tetraspanin CD9, 109, 2019 | 1 | 2019 |
Expanding Differential Ion Mobility Separations into the MegaDalton Range TP Wörner, HA Thurman, AA Makarov, AA Shvartsburg Analytical Chemistry, 2024 | | 2024 |
To 200,000 m/z and beyond: native electron capture charge reduction mass spectrometry deconvolves heterogeneous signals in large biopharmaceutical analytes KIP Le Huray, TP Woerner, T Moreira, M Reinhardt-Szyba, PWA Devine, ... bioRxiv, 2024.02. 19.581059, 2024 | | 2024 |
Giants in Orbit: Orbitrap based native MS studies on large biomolecules TP Wörner Utrecht University, 2022 | | 2022 |