Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases DJ Rawlings, AM Scharenberg, H Park, MI Wahl, S Lin, RM Kato, ... Science 271 (5250), 822-825, 1996 | 558 | 1996 |
Btk/Tec kinases regulate sustained increases in intracellular Ca2+ following B-cell receptor activation AC Fluckiger, Z Li, RM Kato, MI Wahl, HD Ochs, R Longnecker, JP Kinet, ... The EMBO journal 17 (7), 1973-1985, 1998 | 509 | 1998 |
PKC-β controls IκB kinase lipid raft recruitment and activation in response to BCR signaling TT Su, B Guo, Y Kawakami, K Sommer, K Chae, LA Humphries, RM Kato, ... Nature immunology 3 (8), 780-786, 2002 | 426 | 2002 |
Engagement of the human Pre-B cell receptor generates a lipid raft–dependent calcium signaling complex B Guo, RM Kato, M Garcia-Lloret, MI Wahl, DJ Rawlings Immunity 13 (2), 243-253, 2000 | 307 | 2000 |
Protein Kinase C βII Regulates Akt Phosphorylation on Ser-473 in a Cell Type-and Stimulus-specific Fashion*♦ Y Kawakami, H Nishimoto, J Kitaura, M Maeda-Yamamoto, RM Kato, ... Journal of Biological Chemistry 279 (46), 47720-47725, 2004 | 244 | 2004 |
Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation Y Kawakami, J Kitaura, AB Satterthwaite, RM Kato, K Asai, SE Hartman, ... The Journal of Immunology 165 (3), 1210-1219, 2000 | 202 | 2000 |
Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties FD Goldman, AL Gilman, C Hollenback, RM Kato, BA Premack, ... Blood, The Journal of the American Society of Hematology 95 (11), 3460-3466, 2000 | 202 | 2000 |
PKCβ modulates antigen receptor signaling via regulation of Btk membrane localization SW Kang, MI Wahl, J Chu, J Kitaura, Y Kawakami, RM Kato, R Tabuchi, ... The EMBO journal, 2001 | 188 | 2001 |
Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cγ Src homology 2-Src homology 3 linker LA Humphries, C Dangelmaier, K Sommer, K Kipp, RM Kato, N Griffith, ... Journal of Biological Chemistry 279 (36), 37651-37661, 2004 | 169 | 2004 |
Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors MI Wahl, AC Fluckiger, RM Kato, H Park, ON Witte, DJ Rawlings Proceedings of the National Academy of Sciences 94 (21), 11526-11533, 1997 | 157 | 1997 |
Trace incorporation of heavy water reveals slow and heterogeneous pathogen growth rates in cystic fibrosis sputum SH Kopf, AL Sessions, ES Cowley, C Reyes, L Van Sambeek, Y Hu, ... Proceedings of the National Academy of Sciences 113 (2), E110-E116, 2016 | 122 | 2016 |
Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer PW Yu, RS Tabuchi, RM Kato, A Astrakhan, S Humblet-Baron, K Kipp, ... Blood 104 (5), 1281-1290, 2004 | 110 | 2004 |
A Ras activation pathway dependent on Syk phosphorylation of protein kinase C Y Kawakami, J Kitaura, L Yao, RW McHenry, Y Kawakami, AC Newton, ... Proceedings of the National Academy of Sciences 100 (16), 9470-9475, 2003 | 101 | 2003 |
Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases. L Cohen, R Mohr, YY Chen, M Huang, R Kato, D Dorin, F Tamanoi, ... Proceedings of the National Academy of Sciences 91 (26), 12448-12452, 1994 | 98 | 1994 |
Long-term culture system for selective growth of human B-cell progenitors. DJ Rawlings, SG Quan, RM Kato, ON Witte Proceedings of the National Academy of Sciences 92 (5), 1570-1574, 1995 | 91 | 1995 |
Constitutive membrane association potentiates activation of Bruton tyrosine kinase T Li, DJ Rawlings, H Park, RM Kato, ON Witte, AB Satterthwaite Oncogene 15 (12), 1375-1383, 1997 | 90 | 1997 |
In situ detection of activated Bruton’s tyrosine kinase in the Ig signaling complex by phosphopeptide-specific monoclonal antibodies S Nisitani, RM Kato, DJ Rawlings, ON Witte, MI Wahl Proceedings of the National Academy of Sciences 96 (5), 2221-2226, 1999 | 88 | 1999 |
In Vitro Reconstitution of Human B-Cell Ontogeny: From CD34+ Multipotent Progenitors to Ig-Secreting Cells AC Fluckiger, E Sanz, M Garcia-Lloret, T Su, QL Hao, R Kato, S Quan, ... Blood, The Journal of the American Society of Hematology 92 (12), 4509-4520, 1998 | 77 | 1998 |
Chronic transfusion therapy improves but does not normalize systemic and pulmonary vasculopathy in sickle cell disease JA Detterich, RM Kato, M Rabai, HJ Meiselman, TD Coates, JC Wood Blood, The Journal of the American Society of Hematology 126 (6), 703-710, 2015 | 75 | 2015 |
Peripheral vasoconstriction and abnormal parasympathetic response to sighs and transient hypoxia in sickle cell disease S Sangkatumvong, MCK Khoo, R Kato, JA Detterich, A Bush, TG Keens, ... American journal of respiratory and critical care medicine 184 (4), 474-481, 2011 | 58 | 2011 |