Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy RD Sentelle, CE Senkal, W Jiang, S Ponnusamy, S Gencer, ... Nature chemical biology 8 (10), 831-838, 2012 | 540 | 2012 |
The diverse roles of arrestin scaffolds in G protein–coupled receptor signaling YK Peterson, LM Luttrell Pharmacological reviews 69 (3), 256-297, 2017 | 435 | 2017 |
Sphingosine analogue drug FTY720 targets I2PP2A/SET and mediates lung tumour suppression via activation of PP2A‐RIPK1‐dependent necroptosis SA Saddoughi, S Gencer, YK Peterson, KE Ward, A Mukhopadhyay, ... EMBO molecular medicine 5 (1), 105-121, 2013 | 301 | 2013 |
Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo M Gotta, Y Dong, YK Peterson, SM Lanier, J Ahringer Current biology 13 (12), 1029-1037, 2003 | 294 | 2003 |
Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking MS Bowers, K McFarland, RW Lake, YK Peterson, CC Lapish, ... Neuron 42 (2), 269-281, 2004 | 266 | 2004 |
The conformational signature of β-arrestin2 predicts its trafficking and signalling functions MH Lee, KM Appleton, EG Strungs, JY Kwon, TA Morinelli, YK Peterson, ... Nature 531 (7596), 665-668, 2016 | 230 | 2016 |
Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins ML Bernard, YK Peterson, P Chung, J Jourdan, SM Lanier Journal of Biological Chemistry 276 (2), 1585-1593, 2001 | 174 | 2001 |
Stabilization of the GDP-bound conformation of Giα by a peptide derived from the G-protein regulatory motif of AGS3 YK Peterson, ML Bernard, H Ma, S Hazard, SG Graber, SM Lanier Journal of Biological Chemistry 275 (43), 33193-33196, 2000 | 170 | 2000 |
Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning AP Leonard, RB Cameron, JL Speiser, BJ Wolf, YK Peterson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (2), 348-360, 2015 | 165 | 2015 |
Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation S Panneer Selvam, RM De Palma, JJ Oaks, N Oleinik, YK Peterson, ... Science signaling 8 (381), ra58-ra58, 2015 | 142 | 2015 |
AGS3 inhibits GDP dissociation from Gα subunits of the Gi family and rhodopsin-dependent activation of transducin M Natochin, B Lester, YK Peterson, ML Bernard, SM Lanier, NO Artemyev Journal of Biological Chemistry 275 (52), 40981-40985, 2000 | 129 | 2000 |
Characterization of isoenzyme-selective inhibitors of human sphingosine kinases P Gao, YK Peterson, RA Smith, CD Smith Public Library of Science 7 (9), e44543, 2012 | 128 | 2012 |
The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis LP Wills, RE Trager, GC Beeson, CC Lindsey, YK Peterson, CC Beeson, ... Journal of Pharmacology and Experimental Therapeutics 342 (1), 106-118, 2012 | 123 | 2012 |
Development of allosteric hydrazide-containing class I histone deacetylase inhibitors for use in acute myeloid leukemia JJ McClure, C Zhang, ES Inks, YK Peterson, J Li, CJ Chou Journal of medicinal chemistry 59 (21), 9942-9959, 2016 | 90 | 2016 |
A novel protein geranylgeranyltransferase-I inhibitor with high potency, selectivity, and cellular activity YK Peterson, P Kelly, CA Weinbaum, PJ Casey Journal of biological chemistry 281 (18), 12445-12450, 2006 | 84 | 2006 |
Receptor-and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation M Ghosh, YK Peterson, SM Lanier, AV Smrcka Journal of Biological Chemistry 278 (37), 34747-34750, 2003 | 82 | 2003 |
Class I HDAC inhibitors display different antitumor mechanism in leukemia and prostatic cancer cells depending on their p53 status X Li, YK Peterson, ES Inks, RA Himes, J Li, Y Zhang, X Kong, CJ Chou Journal of medicinal chemistry 61 (6), 2589-2603, 2018 | 77 | 2018 |
Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G … JB Blumer, ML Bernard, YK Peterson, J Nezu, P Chung, DJ Dunican, ... Journal of Biological Chemistry 278 (26), 23217-23220, 2003 | 72 | 2003 |
Identification of selected therapeutic agents as inhibitors of carboxylesterase 1: potential sources of metabolic drug interactions HJ Zhu, DI Appel, YK Peterson, Z Wang, JS Markowitz Toxicology 270 (2-3), 59-65, 2010 | 65 | 2010 |
Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins YK Peterson, S Hazard, SG Graber, SM Lanier Journal of Biological Chemistry 277 (9), 6767-6770, 2002 | 62 | 2002 |