Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators L Tian, SA Hires, T Mao, D Huber, ME Chiappe, SH Chalasani, ... Nature methods 6 (12), 875-881, 2009 | 2300 | 2009 |
Optimization of a GCaMP calcium indicator for neural activity imaging J Akerboom, TW Chen, TJ Wardill, L Tian, JS Marvin, S Mutlu, ... Journal of neuroscience 32 (40), 13819-13840, 2012 | 1473 | 2012 |
An optimized fluorescent probe for visualizing glutamate neurotransmission JS Marvin, BG Borghuis, L Tian, J Cichon, MT Harnett, J Akerboom, ... Nature methods 10 (2), 162-170, 2013 | 1000 | 2013 |
Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors T Patriarchi, JR Cho, K Merten, MW Howe, A Marley, WH Xiong, RW Folk, ... Science 360 (6396), eaat4422, 2018 | 906 | 2018 |
Functional imaging of hippocampal place cells at cellular resolution during virtual navigation DA Dombeck, CD Harvey, L Tian, LL Looger, DW Tank Nature neuroscience 13 (11), 1433-1440, 2010 | 895 | 2010 |
Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics J Akerboom, N Carreras Calderón, L Tian, S Wabnig, M Prigge, J Tolö, ... Frontiers in molecular neuroscience 6, 2, 2013 | 859 | 2013 |
Dissociable dopamine dynamics for learning and motivation A Mohebi, JR Pettibone, AA Hamid, JMT Wong, LT Vinson, T Patriarchi, ... Nature 570 (7759), 65-70, 2019 | 590 | 2019 |
Multiple dynamic representations in the motor cortex during sensorimotor learning D Huber, DA Gutnisky, S Peron, DH O’connor, JS Wiegert, L Tian, ... Nature 484 (7395), 473-478, 2012 | 562 | 2012 |
An unstructured initiation site is required for efficient proteasome-mediated degradation S Prakash, L Tian, KS Ratliff, RE Lehotzky, A Matouschek Nature structural & molecular biology 11 (9), 830-837, 2004 | 528 | 2004 |
A Cre-dependent GCaMP3 reporter mouse for neuronal imaging in vivo HA Zariwala, BG Borghuis, TM Hoogland, L Madisen, L Tian, ... Journal of Neuroscience 32 (9), 3131-3141, 2012 | 425 | 2012 |
A neural circuit mechanism for encoding aversive stimuli in the mesolimbic dopamine system JW de Jong, SA Afjei, IP Dorocic, JR Peck, C Liu, CK Kim, L Tian, ... Neuron 101 (1), 133-151. e7, 2019 | 415 | 2019 |
Crystal structures of the GCaMP calcium sensor reveal the mechanism of fluorescence signal change and aid rational design J Akerboom, JDV Rivera, MMR Guilbe, ECA Malavé, HH Hernandez, ... Journal of biological chemistry 284 (10), 6455-6464, 2009 | 382 | 2009 |
Activity in motor–sensory projections reveals distributed coding in somatosensation L Petreanu, DA Gutnisky, D Huber, N Xu, DH O’Connor, L Tian, L Looger, ... Nature 489 (7415), 299-303, 2012 | 354 | 2012 |
Imaging neuronal activity with genetically encoded calcium indicators L Tian, SA Hires, LL Looger Cold Spring Harbor Protocols 2012 (6), pdb. top069609, 2012 | 222 | 2012 |
Monitoring activity in neural circuits with genetically encoded indicators GJ Broussard, R Liang, L Tian Frontiers in molecular neuroscience 7, 97, 2014 | 192 | 2014 |
Selective esterase–ester pair for targeting small molecules with cellular specificity L Tian, Y Yang, LM Wysocki, AC Arnold, A Hu, B Ravichandran, ... Proceedings of the National Academy of Sciences 109 (13), 4756-4761, 2012 | 185 | 2012 |
In vivo measurement of afferent activity with axon-specific calcium imaging GJ Broussard, Y Liang, M Fridman, EK Unger, G Meng, X Xiao, N Ji, ... Nature neuroscience 21 (9), 1272-1280, 2018 | 175 | 2018 |
An expanded palette of dopamine sensors for multiplex imaging in vivo T Patriarchi, A Mohebi, J Sun, A Marley, R Liang, C Dong, K Puhger, ... Nature methods 17 (11), 1147-1155, 2020 | 170 | 2020 |
Wnt regulates proliferation and neurogenic potential of Müller glial cells via a Lin28/let-7 miRNA-dependent pathway in adult mammalian retinas K Yao, S Qiu, L Tian, WD Snider, JG Flannery, DV Schaffer, B Chen Cell reports 17 (1), 165-178, 2016 | 162 | 2016 |
Reporting neural activity with genetically encoded calcium indicators SA Hires, L Tian, LL Looger Brain cell biology 36, 69-86, 2008 | 160 | 2008 |