| Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapy JD Leverson, DC Phillips, MJ Mitten, ER Boghaert, D Diaz, SK Tahir, ... Science translational medicine 7 (279), 279ra40-279ra40, 2015 | 546 | 2015 |
| Breast cancer metastasis suppressor 1 up-regulates miR-146, which suppresses breast cancer metastasis DR Hurst, MD Edmonds, GK Scott, CC Benz, KS Vaidya, DR Welch Cancer research 69 (4), 1279-1283, 2009 | 518 | 2009 |
| Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy KT Nash, PA Phadke, JM Navenot, DR Hurst, MA Accavitti-Loper, E Sztul, ... Journal of the National Cancer Institute 99 (4), 309-321, 2007 | 193 | 2007 |
| Metastasis suppressors genes in cancer LJ Stafford, KS Vaidya, DR Welch The international journal of biochemistry & cell biology 40 (5), 874-891, 2008 | 192 | 2008 |
| ABT-414, an antibody–drug conjugate targeting a tumor-selective EGFR epitope AC Phillips, ER Boghaert, KS Vaidya, MJ Mitten, S Norvell, HD Falls, ... Molecular cancer therapeutics 15 (4), 661-669, 2016 | 184 | 2016 |
| Inhibition of CXCR4 by CTCE-9908 inhibits breast cancer metastasis to lung and bone MM Richert, KS Vaidya, CN Mills, D Wong, W Korz, DR Hurst, DR Welch Oncology reports 21 (3), 761-767, 2009 | 175 | 2009 |
| BRMS1 suppresses breast cancer experimental metastasis to multiple organs by inhibiting several steps of the metastatic process PA Phadke, KS Vaidya, KT Nash, DR Hurst, DR Welch The American journal of pathology 172 (3), 809-817, 2008 | 138 | 2008 |
| ABBV-399, a c-Met Antibody–Drug Conjugate that Targets Both MET–Amplified and c-Met–Overexpressing Tumors, Irrespective of MET Pathway Dependence J Wang, MG Anderson, A Oleksijew, KS Vaidya, ER Boghaert, L Tucker, ... Clinical Cancer Research 23 (4), 992-1000, 2017 | 107 | 2017 |
| Breast cancer metastasis suppressor 1 coordinately regulates metastasis‐associated microRNA expression MD Edmonds, DR Hurst, KS Vaidya, LJ Stafford, D Chen, DR Welch International Journal of Cancer 125 (8), 1778-1785, 2009 | 106 | 2009 |
| Metastasis suppressor KISS1 seems to reverse the Warburg effect by enhancing mitochondrial biogenesis W Liu, BH Beck, KS Vaidya, KT Nash, KP Feeley, SW Ballinger, ... Cancer research 74 (3), 954-963, 2014 | 89 | 2014 |
| Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines YJ Kwon, DR Hurst, AD Steg, K Yuan, KS Vaidya, DR Welch, AR Frost Clinical & experimental metastasis 28, 437-449, 2011 | 87 | 2011 |
| Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells DR Hurst, Y Xie, KS Vaidya, A Mehta, BP Moore, MA Accavitti-Loper, ... Journal of Biological Chemistry 283 (12), 7438-7444, 2008 | 84 | 2008 |
| Breast cancer metastasis suppressor-1 differentially modulates growth factor signaling KS Vaidya, S Harihar, PA Phadke, LJ Stafford, DR Hurst, DG Hicks, ... Journal of Biological Chemistry 283 (42), 28354-28360, 2008 | 73 | 2008 |
| BRMS1 suppresses breast cancer metastasis in multiple experimental models of metastasis by reducing solitary cell survival and inhibiting growth initiation BD Hedley, KS Vaidya, P Phadke, L MacKenzie, DW Dales, CO Postenka, ... Clinical & experimental metastasis 25, 727-740, 2008 | 58 | 2008 |
| Metastasis suppressors and their roles in breast carcinoma KS Vaidya, DR Welch Journal of mammary gland biology and neoplasia 12, 175-190, 2007 | 55 | 2007 |
| Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition TM Bodenstine, KS Vaidya, A Ismail, BH Beck, LM Cook, AR Diers, ... Cancer research 70 (23), 10002-10011, 2010 | 53 | 2010 |
| Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification J Wang, L Goetsch, L Tucker, Q Zhang, A Gonzalez, KS Vaidya, ... BMC cancer 16, 1-14, 2016 | 52 | 2016 |
| Calcitonin increases invasiveness of prostate cancer cells: Role for cyclic AMP‐dependent protein kinase A in calcitonin action VS Sabbisetti, S Chirugupati, S Thomas, KS Vaidya, D Reardon, ... International journal of cancer 117 (4), 551-560, 2005 | 49 | 2005 |
| Characterization of ABBV-221, a tumor-selective EGFR-targeting antibody drug conjugate AC Phillips, ER Boghaert, KS Vaidya, HD Falls, MJ Mitten, PJ DeVries, ... Molecular cancer therapeutics 17 (4), 795-805, 2018 | 48 | 2018 |
| Over-expression of the BRMS1 family member SUDS3 does not suppress metastasis of human cancer cells AC Silveira, DR Hurst, KS Vaidya, DE Ayer, DR Welch Cancer letters 276 (1), 32-37, 2009 | 44 | 2009 |
Douglas R. HurstAmerican Cancer Society在 cancer.org 的电子邮件经过验证
