Microbial and animal rhodopsins: structures, functions, and molecular mechanisms OP Ernst, DT Lodowski, M Elstner, P Hegemann, LS Brown, H Kandori Chemical reviews 114 (1), 126-163, 2014 | 1150 | 2014 |
Crystal structure of a photoactivated deprotonated intermediate of rhodopsin D Salom, DT Lodowski, RE Stenkamp, IL Trong, M Golczak, ... Proceedings of the National Academy of Sciences 103 (44), 16123-16128, 2006 | 537 | 2006 |
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gßγ DT Lodowski, JA Pitcher, WD Capel, RJ Lefkowitz, JJG Tesmer Science 300 (5623), 1256-1262, 2003 | 470 | 2003 |
The significance of G protein-coupled receptor crystallography for drug discovery JA Salon, DT Lodowski, K Palczewski Pharmacological reviews 63 (4), 901-937, 2011 | 266 | 2011 |
Structure of the full-length TRPV2 channel by cryo-EM KW Huynh, MR Cohen, J Jiang, A Samanta, DT Lodowski, ZH Zhou, ... Nature communications 7 (1), 11130, 2016 | 214 | 2016 |
Assembly of a GPCR-G protein complex Y Du, NM Duc, SGF Rasmussen, D Hilger, X Kubiak, L Wang, J Bohon, ... Cell 177 (5), 1232-1242. e11, 2019 | 192 | 2019 |
Activation of G protein–coupled receptors: beyond two-state models and tertiary conformational changes PSH Park, DT Lodowski, K Palczewski Annu. Rev. Pharmacol. Toxicol. 48 (1), 107-141, 2008 | 192 | 2008 |
Crystal structure of native RPE65, the retinoid isomerase of the visual cycle PD Kiser, M Golczak, DT Lodowski, MR Chance, K Palczewski Proceedings of the National Academy of Sciences 106 (41), 17325-17330, 2009 | 163 | 2009 |
Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1 N Mast, AJ Annalora, DT Lodowski, K Palczewski, CD Stout, IA Pikuleva Journal of Biological Chemistry 286 (7), 5607-5613, 2011 | 143 | 2011 |
The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs DT Lodowski, VM Tesmer, JL Benovic, JJG Tesmer Journal of Biological Chemistry 281 (24), 16785-16793, 2006 | 124 | 2006 |
Structural basis of TRPV5 channel inhibition by econazole revealed by cryo-EM TET Hughes, DT Lodowski, KW Huynh, A Yazici, J Del Rosario, A Kapoor, ... Nature structural & molecular biology 25 (1), 53-60, 2018 | 118 | 2018 |
Structural basis for the acyltransferase activity of lecithin: retinol acyltransferase-like proteins M Golczak, PD Kiser, AE Sears, DT Lodowski, WS Blaner, K Palczewski Journal of Biological Chemistry 287 (28), 23790-23807, 2012 | 82 | 2012 |
Chemokine receptors and other G protein-coupled receptors DT Lodowski, K Palczewski Current opinion in HIV and AIDS 4 (2), 88-95, 2009 | 80 | 2009 |
Importance of membrane structural integrity for RPE65 retinoid isomerization activity M Golczak, PD Kiser, DT Lodowski, A Maeda, K Palczewski Journal of biological chemistry 285 (13), 9667-9682, 2010 | 77 | 2010 |
Structure of human G protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol JJG Tesmer, VM Tesmer, DT Lodowski, H Steinhagen, J Huber Journal of medicinal chemistry 53 (4), 1867-1870, 2010 | 75 | 2010 |
The role of Gβγ and domain interfaces in the activation of G protein-coupled receptor kinase 2 DT Lodowski, JF Barnhill, RM Pyskadlo, R Ghirlando, R Sterne-Marr, ... Biochemistry 44 (18), 6958-6970, 2005 | 67 | 2005 |
Comparative Analysis of GPCR Crystal Structures† DT Lodowski, TE Angel, K Palczewski Photochemistry and photobiology 85 (2), 425-430, 2009 | 66 | 2009 |
Improvements in G protein-coupled receptor purification yield light stable rhodopsin crystals D Salom, I Le Trong, E Pohl, JA Ballesteros, RE Stenkamp, K Palczewski, ... Journal of structural biology 156 (3), 497-504, 2006 | 64 | 2006 |
Novel RDH12 mutations associated with Leber congenital amaurosis and cone-rod dystrophy: biochemical and clinical evaluations W Sun, C Gerth, A Maeda, DT Lodowski, L Van Der Kraak, DA Saperstein, ... Vision research 47 (15), 2055-2066, 2007 | 62 | 2007 |
Rhodopsin–transducin heteropentamer: Three-dimensional structure and biochemical characterization B Jastrzebska, P Ringler, DT Lodowski, V Moiseenkova-Bell, M Golczak, ... Journal of structural biology 176 (3), 387-394, 2011 | 60 | 2011 |