| Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists Z Gao, Z Li, SP Baker, RD Lasley, S Meyer, E Elzein, V Palle, JA Zablocki, ... Journal of Pharmacology and Experimental therapeutics 298 (1), 209-218, 2001 | 146 | 2001 |
| Synthesis, Antifolate, and Antitumor Activities of Classical and Nonclassical 2-Amino-4-oxo-5-substituted-pyrrolo[2,3-d]pyrimidines A Gangjee, A Vidwans, E Elzein, JJ McGuire, SF Queener, RL Kisliuk Journal of medicinal chemistry 44 (12), 1993-2003, 2001 | 121 | 2001 |
| A1 Adenosine Receptor Antagonists, Agonists, and Allosteric Enhancers WF Kiesman, E Elzein, J Zablocki Adenosine receptors in health and disease, 25-58, 2009 | 120 | 2009 |
| A1 adenosine receptor agonists and their potential therapeutic applications E Elzein, J Zablocki Expert opinion on investigational drugs 17 (12), 1901-1910, 2008 | 118 | 2008 |
| Novel 1,3-Disubstituted 8-(1-benzyl-1H-pyrazol-4-yl) Xanthines: High Affinity and Selective A2B Adenosine Receptor Antagonists RV Kalla, E Elzein, T Perry, X Li, V Palle, V Varkhedkar, A Gimbel, T Maa, ... Journal of medicinal chemistry 49 (12), 3682-3692, 2006 | 84 | 2006 |
| N-pyrazole A2A adenosine receptor agonists JA Zablocki, EO Elzein, VP Palle US Patent 6,403,567, 2002 | 83 | 2002 |
| Discovery of a Novel A2B Adenosine Receptor Antagonist as a Clinical Candidate for Chronic Inflammatory Airway Diseases E Elzein, RV Kalla, X Li, T Perry, A Gimbel, D Zeng, D Lustig, K Leung, ... Journal of medicinal chemistry 51 (7), 2267-2278, 2008 | 81 | 2008 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,825,349, 2004 | 80 | 2004 |
| Classical and nonclassical antifolates as potential antitumor, antipneumocystis and antitoxoplasma agents A Gangjee, E Elzein, M Kothare, A Vasudevan Current Pharmaceutical Design 2 (3), 263-280, 1996 | 72 | 1996 |
| A2B adenosine receptor antagonists R Kalla, T Perry, E Elzein, V Varkhedkar, X Li, P Ibrahim, V Palle, D Xiao, ... US Patent 6,977,300, 2005 | 71 | 2005 |
| Fused heterocyclic compounds as ion channel modulators B Corkey, E Elzein, R Jiang, R Kalla, T Kobayashi, D Koltun, X Li, G Notte, ... US Patent 8,952,034, 2015 | 64 | 2015 |
| C-pyrazole 2A A receptor agonists JA Zablocki, VP Palle, EO Elzein US Patent 6,214,807, 2001 | 60 | 2001 |
| Novel 1, 3-dipropyl-8-(1-heteroarylmethyl-1H-pyrazol-4-yl)-xanthine derivatives as high affinity and selective A2B adenosine receptor antagonists E Elzein, R Kalla, X Li, T Perry, E Parkhill, V Palle, V Varkhedkar, ... Bioorganic & medicinal chemistry letters 16 (2), 302-306, 2006 | 58 | 2006 |
| Substituted piperazine compounds J Zablocki, E Elzein, G Nudelman, T Marquart, BK Blackburn, VP Palle US Patent 6,677,336, 2004 | 54 | 2004 |
| Selective, high affinity A2B adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl) xanthines RV Kalla, E Elzein, T Perry, X Li, A Gimbel, M Yang, D Zeng, J Zablocki Bioorganic & medicinal chemistry letters 18 (4), 1397-1401, 2008 | 51 | 2008 |
| 2-Pyrazolyl-N6-Substituted Adenosine Derivatives as High Affinity and Selective Adenosine A3 Receptor Agonists E Elzein, V Palle, Y Wu, T Maa, D Zeng, J Zablocki Journal of medicinal chemistry 47 (19), 4766-4773, 2004 | 50 | 2004 |
| Aralkyl substituted piperazine compounds J Zablocki, E Elzein, BK Blackburn, T Marquart, PN Ibrahim, VP Palle US Patent 6,552,023, 2003 | 50 | 2003 |
| A2B adenosine receptor antagonists E Elzein, R Kalla, T Marquart, J Zablocki, X Li US Patent 7,125,993, 2006 | 49 | 2006 |
| 2-SUBSTITUTED PI SYSTEM DERIVATIVES OF ADENOSINE THAT ARE CORONARY VASODILATORS ACTING VIA THE A2A ADENOSINE RECEPTOR J Zablocki, V Palle, B Blackburn, E Elzein, G Nudelman, S Gothe, Z Gao, ... Nucleosides, Nucleotides and Nucleic Acids 20 (4-7), 343-360, 2001 | 45 | 2001 |
| Synthesis and Biological Activities of Tricyclic Conformationally Restricted Tetrahydropyrido Annulated Furo[2,3-d]pyrimidines as Inhibitors of Dihydrofolate … A Gangjee, E Elzein, SF Queener, JJ McGuire Journal of medicinal chemistry 41 (9), 1409-1416, 1998 | 45 | 1998 |
