mRNA vaccines for infectious diseases: principles, delivery and clinical translation N Chaudhary, D Weissman, KA Whitehead Nature reviews Drug discovery 20 (11), 817-838, 2021 | 800 | 2021 |
The replacement of helper lipids with charged alternatives in lipid nanoparticles facilitates targeted mRNA delivery to the spleen and lungs ST LoPresti, ML Arral, N Chaudhary, KA Whitehead Journal of Controlled Release 345, 819-831, 2022 | 115 | 2022 |
A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo KA Hajj, JR Melamed, N Chaudhary, NG Lamson, RL Ball, SS Yerneni, ... Nano letters 20 (7), 5167-5175, 2020 | 90 | 2020 |
Ionizable lipid nanoparticles deliver mRNA to pancreatic β cells via macrophage-mediated gene transfer JR Melamed, SS Yerneni, ML Arral, ST LoPresti, N Chaudhary, ... Science Advances 9 (4), eade1444, 2023 | 57 | 2023 |
Lipid nanoparticle chemistry determines how nucleoside base modifications alter mRNA delivery JR Melamed, KA Hajj, N Chaudhary, D Strelkova, ML Arral, N Pardi, ... Journal of Controlled Release 341, 206-214, 2022 | 45 | 2022 |
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology JP Gleeson, KC Fein, N Chaudhary, R Doerfler, AN Newby, ... International journal of pharmaceutics 593, 120120, 2021 | 22 | 2021 |
Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations JP Gleeson, N Chaudhary, KC Fein, R Doerfler, P Hredzak-Showalter, ... Science Advances 8 (26), eabm6865, 2022 | 19 | 2022 |
Author Correction: mRNA vaccines for infectious diseases: principles, delivery and clinical translation N Chaudhary, D Weissman, KA Whitehead Nature reviews. Drug discovery 20 (11), 880, 2021 | 17 | 2021 |
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery NG Lamson, KC Fein, JP Gleeson, AN Newby, S Xian, K Cochran, ... Proceedings of the National Academy of Sciences 119 (33), e2207829119, 2022 | 13 | 2022 |
The mixing method used to formulate lipid nanoparticles affects mRNA delivery efficacy and organ tropism DMS Petersen, N Chaudhary, ML Arral, RM Weiss, KA Whitehead European Journal of Pharmaceutics and Biopharmaceutics 192, 126-135, 2023 | 11 | 2023 |
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... Proceedings of the National Academy of Sciences 121 (11), e2307810121, 2024 | 6 | 2024 |
Lipid nanoparticle structure and delivery route during pregnancy dictates mRNA potency, immunogenicity, and health in the mother and offspring N Chaudhary, AN Newby, ML Arral, SS Yerneni, ST LoPresti, R Doerfler, ... bioRxiv, 2023.02. 15.528720, 2023 | 5 | 2023 |
From farm to pharmacy: strawberry-enabled oral delivery of protein drugs NG Lamson, KC Fein, JP Gleeson, S Xian, A Newby, N Chaudhary, ... bioRxiv, 2020.03. 11.987461, 2020 | 4 | 2020 |
Factor XII silencing using siRNA prevents thrombus formation in a rat model of extracorporeal life support N Umei, S Shin, A Lai, J Miller, K Roberts, D Strelkova, N Chaudhary, ... ASAIO Journal 69 (6), 527-532, 2023 | 1 | 2023 |
Profiling of mature stage human breastmilk cells identifies host-defense lactocyte sub-populations JP Gleeson, N Chaudhary, R Doerfler, KC Fein, T Hredzak-Showalter, ... bioRxiv, 2021.10. 04.463125, 2021 | 1 | 2021 |
Characterization and comparison of human and mouse milk cells R Doerfler, S Yerneni, A Newby, N Chaudhary, A Shu, K Fein, ... Plos one 19 (1), e0297821, 2024 | | 2024 |
Non‐Viral RNA Delivery During Pregnancy: Opportunities and Challenges N Chaudhary, AN Newby, KA Whitehead Small, 2306134, 2023 | | 2023 |