MYC-driven epigenetic reprogramming favors the onset of tumorigenesis by inducing a stem cell-like state V Poli, L Fagnocchi, A Fasciani, A Cherubini, S Mazzoleni, S Ferrillo, ... Nature communications 9 (1), 1024, 2018 | 140 | 2018 |
SETD5 regulates chromatin methylation state and preserves global transcriptional fidelity during brain development and neuronal wiring A Sessa, L Fagnocchi, G Mastrototaro, L Massimino, M Zaghi, M Indrigo, ... Neuron 104 (2), 271-289. e13, 2019 | 101 | 2019 |
Tumorigenic cell reprogramming and cancer plasticity: interplay between signaling, microenvironment, and epigenetics V Poli, L Fagnocchi, A Zippo Stem cells international 2018, 2018 | 71 | 2018 |
Transcriptional Regulation of the nadA Gene in Neisseria meningitidis Impacts the Prediction of Coverage of a Multicomponent Meningococcal Serogroup B Vaccine L Fagnocchi, A Biolchi, F Ferlicca, G Boccadifuoco, B Brunelli, S Brier, ... Infection and immunity 81 (2), 560-569, 2013 | 68 | 2013 |
MLL4-associated condensates counterbalance Polycomb-mediated nuclear mechanical stress in Kabuki syndrome A Fasciani, S D’Annunzio, V Poli, L Fagnocchi, S Beyes, D Michelatti, ... Nature genetics 52 (12), 1397-1411, 2020 | 67 | 2020 |
A Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identity L Fagnocchi, A Cherubini, H Hatsuda, A Fasciani, S Mazzoleni, V Poli, ... Nature communications 7 (1), 11903, 2016 | 66 | 2016 |
PI3K-driven HER2 expression is a potential therapeutic target in colorectal cancer stem cells LR Mangiapane, A Nicotra, A Turdo, M Gaggianesi, P Bianca, S Di Franco, ... Gut 71 (1), 119-128, 2022 | 56 | 2022 |
The proneural gene ASCL1 governs the transcriptional subgroup affiliation in glioblastoma stem cells by directly repressing the mesenchymal gene NDRG1 A Narayanan, F Gagliardi, AL Gallotti, S Mazzoleni, M Cominelli, ... Cell Death & Differentiation 26 (9), 1813-1831, 2019 | 53 | 2019 |
GADD34 is a modulator of autophagy during starvation G Gambardella, L Staiano, MN Moretti, R De Cegli, L Fagnocchi, ... Science Advances 6 (39), eabb0205, 2020 | 51 | 2020 |
Multiple roles of MYC in integrating regulatory networks of pluripotent stem cells L Fagnocchi, A Zippo Frontiers in Cell and Developmental Biology 5, 7, 2017 | 50 | 2017 |
Integration of signaling pathways with the epigenetic machinery in the maintenance of stem cells L Fagnocchi, S Mazzoleni, A Zippo Stem cells international 2016, 2016 | 41 | 2016 |
In the NadR regulon, adhesins and diverse meningococcal functions are regulated in response to signals in human saliva L Fagnocchi, E Pigozzi, V Scarlato, I Delany Journal of bacteriology 194 (2), 460-474, 2012 | 38 | 2012 |
Enhancer reprogramming in tumor progression: a new route towards cancer cell plasticity L Fagnocchi, V Poli, A Zippo Cellular and Molecular Life Sciences 75, 2537-2555, 2018 | 32 | 2018 |
Molecular basis of ligand-dependent regulation of NadR, the transcriptional repressor of meningococcal virulence factor NadA A Liguori, E Malito, P Lo Surdo, L Fagnocchi, F Cantini, AF Haag, S Brier, ... PLoS pathogens 12 (4), e1005557, 2016 | 26 | 2016 |
Global Transcriptome Analysis Reveals Small RNAs Affecting Neisseria meningitidis Bacteremia L Fagnocchi, S Bottini, G Golfieri, L Fantappie, F Ferlicca, A Antunes, ... PLoS One 10 (5), e0126325, 2015 | 26 | 2015 |
Drosophila VHL tumor-suppressor gene regulates epithelial morphogenesis by promoting microtubule and aPKC stability S Duchi, L Fagnocchi, V Cavaliere, A Hsouna, G Gargiulo, T Hsu Development 137 (9), 1493-1503, 2010 | 24 | 2010 |
Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid S Brier, L Fagnocchi, D Donnarumma, M Scarselli, R Rappuoli, M Nissum, ... Biochemistry 51 (34), 6738-6752, 2012 | 23 | 2012 |
The impact on microtubule network of a bracovirus IκB-like protein S Duchi, V Cavaliere, L Fagnocchi, MR Grimaldi, P Falabella, F Graziani, ... Cellular and molecular life sciences 67, 1699-1712, 2010 | 21 | 2010 |
Independent phenotypic plasticity axes define distinct obesity sub-types CH Yang, L Fagnocchi, S Apostle, V Wegert, S Casaní-Galdón, ... Nature metabolism 4 (9), 1150-1165, 2022 | 17 | 2022 |
Epigenetic dosage identifies two major and functionally distinct β cell subtypes E Dror, L Fagnocchi, V Wegert, S Apostle, B Grimaldi, T Gruber, I Panzeri, ... Cell Metabolism 35 (5), 821-836. e7, 2023 | 16 | 2023 |