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Alexander E Chu
Alexander E Chu
在 stanford.edu 的电子邮件经过验证
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Progen: Language modeling for protein generation
A Madani, B McCann, N Naik, NS Keskar, N Anand, RR Eguchi, ...
arXiv preprint arXiv:2004.03497, 2020
2592020
Soybean cyst nematode resistance emerged via artificial selection of duplicated serine hydroxymethyltransferase genes
XY Wu, GC Zhou, YX Chen, P Wu, LW Liu, FF Ma, M Wu, CC Liu, YJ Zeng, ...
Frontiers in plant science 7, 998, 2016
252016
Optical control of fast and processive engineered myosins in vitro and in living cells
PV Ruijgrok, RP Ghosh, S Zemsky, M Nakamura, R Gong, L Ning, R Chen, ...
Nature chemical biology 17 (5), 540-548, 2021
232021
An all-atom protein generative model
AE Chu, J Kim, L Cheng, G El Nesr, M Xu, RW Shuai, PS Huang
Proceedings of the National Academy of Sciences 121 (27), e2311500121, 2024
202024
Interleukin-2 superkines by computational design
J Ren, AE Chu, KM Jude, LK Picton, AJ Kare, L Su, A Montano Romero, ...
Proceedings of the National Academy of Sciences 119 (12), e2117401119, 2022
182022
Sparks of function by de novo protein design
AE Chu, T Lu, PS Huang
Nature biotechnology 42 (2), 203-215, 2024
152024
De novo design of a highly stable ovoid TIM barrel: Unlocking pocket shape towards functional design
AE Chu, D Fernandez, JJ Liu, RR Eguchi, PS Huang
BioDesign Research, 2022
92022
De novo design of high-affinity protein binders with AlphaProteo
V Zambaldi, D La, AE Chu, H Patani, AE Danson, TOC Kwan, T Frerix, ...
arXiv preprint arXiv:2409.08022, 2024
2024
Learning to Design Protein Structure and Sequence
AE Chu
Stanford University, 2023
2023
Towards a Universal Characterization of the Membrane Protein Expression Landscape
AE Chu, SM Saladi, N Bradbury, WM Clemons
Biophysical Journal 112 (3), 188a, 2017
2017
Statistical Models Robustly Predict Membrane Protein Expression in E. Coli
S Saladi, AE Chu, WM Clemons
Biophysical Journal 112 (3), 356a, 2017
2017
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