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Elena Heng
Elena Heng
Institute of Molecular and Cell Biology (IMCB)
在 imcb.a-star.edu.sg 的电子邮件经过验证
标题
引用次数
引用次数
年份
CRISPR–Cas9 strategy for activation of silent Streptomyces biosynthetic gene clusters
MM Zhang, FT Wong, Y Wang, S Luo, YH Lim, E Heng, WL Yeo, RE Cobb, ...
Nature chemical biology 13 (6), 607-609, 2017
3182017
Auroramycin: A Potent Antibiotic from Streptomyces roseosporus by CRISPR‐Cas9 Activation
YH Lim, FT Wong, WL Yeo, KC Ching, YW Lim, E Heng, S Chen, DJ Tsai, ...
ChemBioChem 19 (16), 1716-1719, 2018
562018
Characterization of Cas proteins for CRISPR‐Cas editing in streptomycetes
WL Yeo, E Heng, LL Tan, YW Lim, YH Lim, S Hoon, H Zhao, MM Zhang, ...
Biotechnology and bioengineering 116 (9), 2330-2338, 2019
402019
CRISPR-Cas strategies for natural product discovery and engineering in actinomycetes
E Heng, LL Tan, MM Zhang, FT Wong
Process Biochemistry 102, 261-268, 2021
132021
Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
WL Yeo, E Heng, LL Tan, YW Lim, KC Ching, DJ Tsai, YW Jhang, ...
Microbial cell factories 19, 1-11, 2020
132020
Identification and engineering of 32 membered antifungal macrolactone notonesomycins
F Goh, MM Zhang, TR Lim, KN Low, CE Nge, E Heng, WL Yeo, FL Sirota, ...
Microbial Cell Factories 19, 1-13, 2020
92020
Enhancing armeniaspirols production through multi-level engineering of a native Streptomyces producer
E Heng, YW Lim, CY Leong, VWP Ng, SB Ng, YH Lim, FT Wong
Microbial cell factories 22 (1), 84, 2023
82023
Exploring a general multi-pronged activation strategy for natural product discovery in Actinomycetes
DWP Tay, LL Tan, E Heng, N Zulkarnain, KC Ching, M Wibowo, EJ Chin, ...
Communications Biology 7 (1), 50, 2024
72024
CRISPR/Cas-Mediated Genome Editing of Streptomyces
LL Tan, E Heng, N Zulkarnain, WC Hsiao, FT Wong, MM Zhang
Recombineering: Methods and Protocols, 207-225, 2022
62022
Nat. Chem. Biol.
MM Zhang, FT Wong, Y Wang, S Luo, YH Lim, E Heng, WL Yeo, RE Cobb, ...
42016
Training old dogs to do new tricks: A general multi-pronged activation approach for natural product discovery in Actinomycetes
D Tay, LL Tan, E Heng, N Zulkarnain, KC Ching, M Wibowo, E Chin, ...
32022
Discovery, characterization, and engineering of an advantageous Streptomyces host for heterologous expression of natural product biosynthetic gene clusters
E Klumbys, W Xu, L Koduru, E Heng, Y Wei, FT Wong, H Zhao, EL Ang
Microbial Cell Factories 23 (1), 149, 2024
22024
Application of Cas12j for Streptomyces Editing
LL Tan, E Heng, CY Leong, V Ng, LK Yang, DCS Seow, L Koduru, ...
Biomolecules 14 (4), 486, 2024
22024
Cost-effective hybrid long-short read assembly delineates alternative GC-rich Streptomyces hosts for natural product discovery
E Heng, LL Tan, DWP Tay, YH Lim, LK Yang, DCS Seow, CY Leong, ...
Synthetic and Systems Biotechnology 8 (2), 253-261, 2023
22023
Tandem mass spectral metabolic profiling of 54 actinobacterial strains and their 459 mutants
DWP Tay, LL Tan, E Heng, N Zulkarnain, EJ Chin, ZYQ Tan, CY Leong, ...
Scientific Data 11 (1), 977, 2024
12024
A linked Genomics Sequencing and Mass Spectrometry multi-modal dataset and models for Streamlined Natural Products Discovery in Microbial Strain Libraries
DWP Tay, W Koh, SJ Ang, ZM Wong, YW Lim, E Heng, NZX Yeo, ...
bioRxiv, 2025.01. 20.633932, 2025
2025
Hyperporous encapsulation of microbes for whole cell biocatalysis and biomanufacturing
J Zhang, K Chang, J Tay, E Tiong, E Heng, T Seah, YW Lim, G Peh, ...
bioRxiv, 2024.06. 18.599529, 2024
2024
Application of Cas12j for Streptomyces editing and cluster activation
LL Tan, E Heng, N Zulkarnain, CY Leong, V Ng, LK Yang, DC San Seow, ...
bioRxiv, 2021.10. 28.465406, 2021
2021
MOESM2 of Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
W Yeo, E Heng, L Tan, Y Lim, K Ching, DJ Tsai, Y Jhang, TL Lauderdale, ...
(No Title), 2020
2020
Biosynthetic engineering of the antifungal, anti-MRSA auroramycin
M Zhang, KC Ching, FT Wong, WL Yeo, YW Jhang, KS Shia, YW Lim, ...
Microbial Cell Factories 19, 2019
2019
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